Prevalence of uterine anomalies and their impact on early pregnancy in women conceiving after assisted reproduction treatment

Abstract

Objective To estimate the prevalence of congenital uterine anomalies in subfertile women and to evaluate their influence on early pregnancy following assisted reproduction treatment (ART). Methods (n = 164 (11.8%)) followed by septate (n = 7 (0.5%)), unicornuate (n = 6 (0.4%)), subseptate (n = 5 (0.4%)), bicornuate (n = 1 (0.1%)) and T-shaped uteri (n = 1 (0.1%)). A total of 440 subjects who underwent ART were followed up. The pregnancy rates in women with arcuate uteri (36/66 (54.5%)) and major uterine anomalies (7/10 (70.0%)) were statistically similar (P = 0.09 and P = 0.11, respectively) to that of the matched controls with normal uteri (158/364 (43.4%)

Bicornuate Bicollis Uterus with Partial Uterine Septum: Case Report

“…MR G uterin anomalilerin tanısını koymada sensitivitesi ve spesifisitesi oldukça yüksek altın standart bir yöntemdir. 7,8 Kara ve ark., çalışmalarında, bikornuat uterusun tekrarlayan gebelik kaybına yol açabileceğini ve gebeliğin sonlandırılması işlemi sırasında uterin perforasyon riskinin arttığını belirtmişlerdir. Ayrıca, bikornuat uterusu olan bir olguda gebelik sonlandırması için medikal abortus yöntemlerinin tercih edilmesini önermişlerdir.…”

3D Ultrasound Assessment of the Uterus: Why an Accuracy Study for Mullerian Congenital Anomalies is not Feasible, while Screening Already is, and should be done

“…Until 2000, the combined use of laparoscopy (LSK) and hysteroscopy (HSK) was considered the gold standard for diagnosis of mullerian duct anomalies, due to the capabilities to assess the external and internal contour, respectively ( Figure 2) [16][17][18][19][20]. Still, in many cases the two investigations are separately performed by different operators, and thus, the diagnosis accuracy may be influenced.…”

The Role of Three-dimensional Ultrasound in the Assessment of Congenital Uterine Anomalies

“…Congenital uterine anomalies are a result of abnormalities that occur along different stages of embryological development. [1][2][3] Agenesis of müllerian ducts, precursors to the cervix, the uterus, upper two-thirds of the vagina and the fallopian tubes, in the initial stages of development lead to unicornuate uterus. Failure or improper lateral fusion of the müllerian ducts can lead to formation of bicornuate or didelphic uteri.…”

“…1 A recent study that used 3D ultrasound for diagnosis, reported that the rate of congenital uterine anomalies is 13.3% in the subfertile female population. 2 One of the few indications that this abnormality is present in a patient is that the miscarriage rate is higher in women with congenital uterine anomalies compared with healthy women. This condition is uncommonly diagnosed because of the different types of imaging used, which has been traditionally quite limited.…”

“…Data from recent study indicate that congenital uterine anomalies are highly prevalent in women seeking assisted reproductive treatment and apparently the most common type of anomaly was arcuate uterus and septate uterus. [2][3][4] 3D ultrasound is highly accurate due to its ability to visualize the uterine cavity and external contours of the uterine myometrium and fundus, which establishes its relevance as a gold imaging method to detect congenital uterine anomalies (Fig. 1).…”