Prevalens meningitis neonatal dan faktor-faktor yang memengaruhi pada bayi klinis sepsis di ruang NICU RSUP Sanglah Denpasar

Rachman, Alissya; Artana, Wayan; Sukmawati, Made

doi:10.15562/medicina.v48i2.38

Cited by 1 publication

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“…In this study, 14.8% of patients with neonatal bacterial meningitis had CSF cells ≤20 cells/mm 3 . This finding is similar to the previous study which found three cases of neonatal meningitis with CSF cells of <20 cells/mm 3 [7]. Prior administration of antibiotics can lead to high levels of CSF glucose and low levels of CSF protein [19].…”

Section: Discussionsupporting

confidence: 92%

“…The risk factor of bacterial meningitis in late-onset neonatal sepsis was gestational age <37 weeks with OR 4.22 (95% CI 1.28-13.86). A similar finding was found in a study of risk factors for neonatal meningitis in clinical sepsis [7]. The risks of neonatal bacterial meningitis increase with decreasing gestational age.…”

Section: Discussionsupporting

confidence: 87%

“…In developing countries, meningitis was found in 2.4-12.7 of 7.1-38 cases of neonatal sepsis per 1000 births [5], [6]. The prevalence of neonatal meningitis in clinical sepsis at the Neonatal Intensive Care Unit, Sanglah General Hospital Denpasar was 68.8% [7]. A study by Arora et al also reported 55 cases of meningitis (61.11%) in 90 patients with suspected late-onset neonatal sepsis [8].…”

Section: Introductionmentioning

confidence: 99%

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The Risk Factors of Bacterial Meningitis in Late-Onset Neonatal Sepsis

Noviyani

Kardana

Mahalini

et al. 2021

Open Access Maced J Med Sci

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BACKGROUND: Neonatal bacterial meningitis has a significant contribution on neonatal morbidity and mortality. It is the most common complication of late-onset neonatal sepsis. An understanding of the risk factors for bacterial meningitis in late-onset neonatal sepsis is required to provide comprehensive management. AIM: To identify the risk factors of bacterial meningitis in late-onset neonatal sepsis. METHODS: This is an analytical study with a case–control design, conducted in May 2019-February 2021, involving neonates aged 4–28 days who suffered from late-onset neonatal sepsis in Level II and III Neonatal Care Unit, Sanglah General Hospital Denpasar. Statistical analysis was performed using Chi-square and logistic regression. RESULTS: A total of 54 patients were analyzed in this study. The mean age of subjects with neonatal bacterial meningitis was 13 days and the majority of them were male (51.9%). The risk factor of bacterial meningitis in late-onset neonatal sepsis was gestational age <37 weeks with odds ratio 4.22 (95% confidence interval 1.28–13.86, p = 0.01). There was no significant association of birth weight <2500 g, neonatal asphyxia, and invasive procedure on neonatal bacterial meningitis. CONCLUSION: Gestational age <37 weeks is a risk factor for bacterial meningitis in late-onset neonatal sepsis.

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Section: Discussionsupporting

confidence: 92%

Section: Discussionsupporting

confidence: 87%