Prevelance of depression and anxiety with their effect on quality of life in chronic kidney disease patients

Abstract

Chronic kidney disease is one of the most common chronic diseases globally. Many studies have shown it is strongly associated with increased social and psychological problems such as depression and anxiety which are considered as common psychiatric disorders that occur in patients with chronic kidney disease. We investigated the prevalence of depression, anxiety and perception of quality of life in a sample of chronic kidney disease patients at the Jordan University Hospital. We aimed to see any association of the mental health in these patients; mainly depression and anxiety with their quality of life and correlation to socio-demographics or laboratory and metabolic profile of this population. 103 chronic kidney disease patients were interviewed using a questionnaire in the Nephrology outpatient clinics of the Jordan University Hospital, the questionnaire included four sections, the first sections handled socio-demographic data. Also, it contains a brief Clinical and laboratory parameter of our patients. The second part consisted of the 9-item Patient Health Questionnaire (PHQ-9) that used to measure the severity of depression. The third part included the 7-item Generalized Anxiety Disorder (GAD-7) to evaluate the severity of anxiety, the fourth part assessed participants quality of life (QOL) using The World Health Organization Quality of Life, Short Form (WHOQOL-BREF) questionnaire. More than half of the participants have depression and anxiety with a percentage of 58.3% and 50.5%, respectively. There was a negative moderate to strong correlation between depression score and quality of life domains scores (p < 0.001).Only marital status had a significant relationship with depression (p < 0.001).Weak positive correlation between Glomerular Filtration Rate and anxiety score (p = 0.04),with significant positive correlation between lipid profile and anxiety score. There was a negative correlation between anxiety score and quality of life domains scores. Females had higher anxiety score than males (p = 0.27). Patients who do not work had a lower physical functioning score compared to others (p value = 0.024).Patients with higher serum Hemoglobin had higher physical and psychological scores. Anxiety, Depression are common among our chronic kidney disease patients, more interventions are needed to improve the mental health of our patients and their quality of life perception. This kind of study allows us to gain a deeper understanding regarding the effects of chronic kidney disease on psychosocial well-being of those patients, and helps health care providers to put depression, anxiety and Quality of life into consideration when treating patients.

Level of Depression and Anxiety on Quality of Life Among Patients Undergoing Hemodialysis

“…In a study conducted by Sameeha et al, the researchers investigated predialysis CKD patients and found the prevalence to be about 58%. 15 It’s well established that depression is the most common psychiatric illness found among hemodialysis patients, in particular with a prevalence that varies between 20% at the lowest to 88.8% at the highest, 2 , 7 , 16–28 while most of the studies have shown the depression prevalence to be around 50% or more. 29 Anxiety is also a common psychiatric disorder among Hemodialysis patients, with a prevalence ranging from 23.6% at the lowest to 92.5% at the highest.…”

“… 17 , 19 , 42–46 Sameeha et al conducted a study in Jordan and found that married CKD patients had a significantly lower prevalence of depression. 15 An interesting study of 3865 participants from 2005–2014 investigated the effect of marital status on depression among CKD patients and found a significant relationship between marital status and mortality among CKD patients. 44 However, some studies have not found any association between marital status with anxiety, depression, or QOL.…”

Penerapan Relaksasi Benson Kombinasi Unsur Keyakinan untuk Menurunkan Kecemasan pada Pasien CKD yang Menjalani Hemodialisa: Studi Kasus

“…17 Hal ini disebabkan beban penyakit, pengobatan seumur hidup, modifikasi diet, dan mahalnya biaya pengobatan, merupakan faktor yang berkontribusi terhadap perubahan status psikologis pasien. 18 Faktor lain yang dapat menyebabkan kecemasan pada Tn. D, yaitu terkait proses hemodialisis yang belum lama dijalani.…”

Design and development of opto‐electrochemical biosensing devices for diagnosing chronic kidney disease

“…Most of the children depend on dialysis or a kidney transplant for their survival which is not simply accessible in developing and underdeveloped nations. Other major issues with CKD are the prevalence of other serious health conditions like cardiovascular diseases, depression, anxiety, and diabetes (Alshelleh et al, 2022; Jankowski et al, 2021). In a recent study, the risk associated with CKD and outcomes after coronary artery bypass surgery was established (Nowrouzi et al, 2022).…”