2022
DOI: 10.1016/j.lana.2022.100256
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Preventable risk factors of dementia: Population attributable fractions in a Brazilian population-based study

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Cited by 19 publications
(38 citation statements)
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References 29 publications
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“…Race‐related risk factors and their PAF should be personally addressed in patients from early ages, adapting interventions and public policies to each population. As presented previously, more than half of dementia cases in Brazil are preventable 4,8 . Race‐related public health strategies should consider race‐specific factors in the design of policies that aim to reduce the incidence of dementia in the coming decades.…”
Section: Discussionmentioning
confidence: 83%
“…Race‐related risk factors and their PAF should be personally addressed in patients from early ages, adapting interventions and public policies to each population. As presented previously, more than half of dementia cases in Brazil are preventable 4,8 . Race‐related public health strategies should consider race‐specific factors in the design of policies that aim to reduce the incidence of dementia in the coming decades.…”
Section: Discussionmentioning
confidence: 83%
“…Model 1 was hypothesis‐driven using 10 described risk factors for dementia. 3 Model 2 was data‐driven, in which variables were included in the model when presenting p < 0.05 in univariate analysis. Odds and prevalence ratios were also calculated for all variables that presented significance in the logistic regression model.…”
Section: Methodsmentioning
confidence: 99%
“…Two multivariate logistic regression models were calculated with SCD as the primary outcome. Model 1 was hypothesis‐driven using 10 described risk factors for dementia 3 . Model 2 was data‐driven, in which variables were included in the model when presenting p < 0.05 in univariate analysis.…”
Section: Methodsmentioning
confidence: 99%
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“…The 2020 Lancet Commission on Dementia Prevention, Intervention and Care, highlighted a number of key modifiable factors including early life low education; midlife hearing loss, traumatic brain injury, hypertension, high alcohol consumption and obesity; and, later-life smoking, depression, social isolation, physical inactivity, air pollution and diabetes that together account for approximately 40% of dementia cases globally [ 2 ]. Preventative strategies to remove cardiovascular disease (e.g., hypertension) and its risk factors including high alcohol intake, diabetes, smoking and physical inactivity would individually eliminate approximately 1–2% of dementia cases globally [ 2 ], with greater effects in Low and Middle Income Countries [ 17 ]. Key non-modifiable factors including age [ 18 , 19 ], gender [ 20 , 21 ], genetics [ 22 ], and ethnicity [ 23 , 24 ] may also modify the association between cardiovascular disease and risk of dementia.…”
Section: Introductionmentioning
confidence: 99%