Preventing the spread of hepatitis B and C viruses: Where are germicides relevant?

Sattar, Syed A.; Tetro, Jason A.; Springthorpe, V S; Giulivi, Antonio

doi:10.1067/mic.2001.114233

Cited by 64 publications

(38 citation statements)

References 73 publications

(80 reference statements)

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“…297 Other enveloped viruses that are somewhat less susceptible, but are killed by 60-70% alcohol, include hepatitis B virus (HBV) and probably hepatitis C virus. 298 In a porcine tissue carrier model used to study antiseptic activity, 70% ethanol and 70% isopropanol were found to reduce titres of an enveloped bacteriophage more effectively than an antimicrobial soap containing 4% CHG. 192 Numerous studies have documented the in vivo antimicrobial activity of alcohols. Early quantitative studies of the effects of antiseptic handrubs established that alcohols effectively reduce bacterial counts on hands.…”

Section: Alcoholsmentioning

confidence: 99%

Hand Hygiene

Longtin¹,

Sax²,

Allegranzi³

et al. 2011

N Engl J Med

108

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Section: Alcoholsmentioning

confidence: 99%

Hand Hygiene

Longtin¹,

Sax²,

Allegranzi³

et al. 2011

N Engl J Med

108

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“…Research investigating chemical disinfectants on surfaces for the prevention of disease spread has focused mainly on the Healthcare and Food industry (Sattar et al, 2000). Discussed below are specific details, from studies, on the known or expected activities of major classes of chemical virucides against VACV.…”

Section: Virucidal Chemicalsmentioning

confidence: 99%

“…Research on VACV has focused mainly in three areas, (1) virus persistence, (2) potency of stored vaccine preparations as well as, (3) disinfection measures and virucidal materials to interrupt the chain of infection for the prevention of disease spread in the Healthcare and Food industry (Sattar et al, 2000). Comparatively, baculovirus studies are agricultural based with direct focus on improving Bio-insecticide performance (Falcon, 1969).…”

Section: Overview Of Factors Influencing Virus Viabilitymentioning

confidence: 99%

Review of Vaccinia Virus and Baculovirus Viability Versus Virucides

Buckley¹,

O’Connell²,

Ouellette³

2008

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“…Hepatitis B virus may be found in body secretions and excreta. The virus shows environmental persistence, and a very small dosage is suffi cient to cause infection 6 . Workers collecting solid wastes can be at risk of HBV infection due to the characteristics of the wastes.…”

Section: Introductionmentioning

confidence: 99%

Is waste collection associated with hepatitis B infection? A meta-analysis

Mol

Cairncross

Greco

et al. 2017

Rev. Soc. Bras. Med. Trop.

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This meta-analysis, which is based on a previously published systematic review, aims to contribute to the scientifi c discussion on hepatitis B virus (HBV) infection in workers who are exposed to domestic and healthcare wastes. Publications were sought which had been made available on the data used by December 2013 and updated to December 2016. The quality of the included studies was assessed according to the guidelines of Loney et al. for the critical appraisal of studies on the prevalence or incidence of a health problem. To verify the presence of heterogeneity between the papers, we used the Chi-squared test based on a Q statistic. A funnel plot was used to test for publication bias. All included studies had across-sectional study design. The association between exposure to waste and positive serology for the HBV surface antigen (HBsAg) showed a signifi cant association [odds ratio (OR) 1.89, 95% confi dence interval (CI) 1.27-2.86; p = 0.0019]. The prevalence rates of HBsAg and anti-HBc seropositivity was 0.04 (95% CI 0.03-0.05) and 0.21 (95% CI 0.14-0.28), respectively (p <0.0001). We found no evidence of publication bias. The results of this meta-analysis indicate a statistically signifi cant association between exposure to solid waste, whether healthcare or domestic, and positive HBV infection markers. Therefore, the working conditions of waste collectors should be analyzed more closely. Immunization against HBV is recommended as the chief preventive measure for all solid waste workers.

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Preventing the spread of hepatitis B and C viruses: Where are germicides relevant?

Cited by 64 publications

References 73 publications

Hand Hygiene

Hand Hygiene

Review of Vaccinia Virus and Baculovirus Viability Versus Virucides

Is waste collection associated with hepatitis B infection? A meta-analysis

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