Prevention of a dangerous tendency in the presentation of the results of GC-MS identification

Potential of chromatography and mass spectrometry for the differentiation of three series of positional isomers of 2‐(dimethoxyphenyl)‐N‐(2‐halogenobenzyl)ethanamines

“…Importantly, GC‐MS is a combined method of analysis, whereas interpretation of its results only on the basis of mass spectra without taking into account chromatographic parameters can lead to erroneous identification results, 55 especially for compounds with similar structures, for example, for isomers. Retention indices are the most reliable and reproducible relative retention parameters of analytes in GC.…”

Chromatographic and chromato–mass spectral characterization of amino acids derivatives formed via the interaction with dimethyl acetal of dimethylformamide

“…The derivatives of the amino acids (pure grade, 1-3 mg) were prepared via the interaction with 50 µL of DMF dimethyl acetal in sealed glass ampoule with length of 40-50 mm and inner diameter of 2 mm upon heating at 80-100°C in the air thermostat of the chromatograph during 1-2 h. The sealing was necessary to prevent losses of volatile DMF dimethyl acetal (bp 102-108°C [5]). The reaction course was visually monitored by the amino acid dissolution.…”