Prevention of Deep Vein Thrombosis by Intermittent Pneumatic Compression of Calf

Hills, Natalie; Pflug, J; Jeyasingh, K.; Boardman, L.; Calnan, James

doi:10.1136/bmj.1.5793.131

Cited by 215 publications

(74 citation statements)

References 20 publications

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“…The majority of trials assessing compression methods were conducted in a surgical setting: 14 were orthopaedic, 24,33,34,36,40,48,49,[51][52][53]59,60,63,64 16 general, 23,25,26,28,29,32,[37][38][39]41,42,44,50,54,61,62 six neurosurgical or after spinal surgery, 31,43,[55][56][57][58] three gynaecological 30,45,46 and one mixed surgical, 47 with only two trials 27,35 conducted among 257 medical patients at high risk of venous thromboembolism. After subdividing these trials into those assessing monotherapy and those assessing adjunctive therapy, the specific type of surgical or medical setting did not appear to influence the effectiveness of mechanical compression [heterogeneity 2 for monotherapy (on 5 df) = 4.6; p > 0.1, and heterogeneity 2 for adjunctive therapy (on 2 df) = 3.7; p > 0.1, not significant (NS); Figure 2].…”

Section: Description Of Trialsmentioning

confidence: 99%

“…In 19 trials [40][41][42][43][44][45][46][47][48][49][50][51][52][53][54][55][56][57][58] among 2255 patients assessing IPC as monotherapy, IPC produced a highly significant 66% (7) reduction in DVT [112/1108 (10.1%) IPC vs 268/1147 (23.4%) control, 2p < 0.00001; Figure 5a]. There was marginal evidence of heterogeneity of effect among these trials ( 2 on 16 df = 28.4; p = 0.03), but this was generated chiefly by one trial.…”

Section: Intermittent Pneumatic Compressionmentioning

confidence: 99%

See 1 more Smart Citation

Towards evidence-based guidelines for the prevention of venous thromboembolism: systematic reviews of mechanical methods, oral anticoagulation, dextran and regional anaesthesia as thromboprophylaxis

Roderick¹,

Ferris²,

Wilson³

et al. 2005

Health Technol Assess

269

151

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Section: Description Of Trialsmentioning

confidence: 99%

Section: Intermittent Pneumatic Compressionmentioning

confidence: 99%

Towards evidence-based guidelines for the prevention of venous thromboembolism: systematic reviews of mechanical methods, oral anticoagulation, dextran and regional anaesthesia as thromboprophylaxis

Roderick¹,

Ferris²,

Wilson³

et al. 2005

Health Technol Assess

269

151

View full text Add to dashboard Cite

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“…Так, у лиц с острым нарушением мозгового кровообращения, сопровождающимся парезами и параличами ниж них конечностей, частота верификации ВТ на фоне стандартной профилактики, включающей эластич ную компрессию, интермиттирующую пневмоком прессию, прямые антикоагулянты, находится в ин тервале 4-23% со средним значением 11,6% [17][18][19][20][21][22][23][24][25]. При хирургическом лечении онкологических заболеваний частота развития ВТ составляет 6,25-55,5% (в среднем 15,9%) на фоне применения анти коагулянтов и компрессионной терапии [26][27][28][29][30][31][32][33][34][35][36]. У больных нейрохирургического профиля на фоне применения механических, фармакологических средств профилактики и их комбинации частота ин струментальной верификации послеоперационных ВТ колеблется от 1,5 до 26,3% и в среднем составля ет 12,5% [37][38][39][40][41][42][43][44][45][46][47].…”

Section: флебология 1 2015unclassified

Toward the individual approach to the evaluation of risks and prevention of postoperative venous thromboembolism

Lobastov¹,

Barinov²,

Laberko³

2015

Flebol.

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“…5,6 Intermittent pneumatic compression using an electromechanical device was introduced in the early 1970s, and several clinical trials have reported its clinical effects since. [7][8][9][10] However, questions about the effectiveness and safety of IPC are still continuously raised. The reason for this may be the lack of a clear scientific causal relationship between IPC and prevention of blood clots.…”

Section: Introductionmentioning

confidence: 99%

Investigation of Blood Flow During Intermittent Pneumatic Compression and Proposal of a New Compression Protocol

Lee

Seo

Kim

et al. 2016

Clin Appl Thromb Hemost

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Introduction: Intermittent pneumatic compression (IPC) is now a widely used therapy for the prophylaxis of deep vein thrombosis and pulmonary embolism. In general, the IPC sequence is composed of sequential compression and simultaneous deflation. Typically, veins are considered to be squeezed and emptied during the compression phase and to be refilled during the deflation phase. However, because the stop or sudden increase in blood flow can be dangerous, a further investigation is needed with respect to the blood flow. Materials and Methods: We demonstrated a new compression protocol based on the investigation results of venous blood flow during IPC. This new compression protocol involves successive compression without the deflation phase; thus, the expelled blood volume flow during a given period can be maximized. To investigate the blood flow during IPC, sonography movie clips and in-laboratory developed blood flow analysis software was used. Results: The increases in the peak volume flow during IPC were 49% (+24%) and 25% (+29%) with the conventional protocol and the new protocol, respectively, whereas the total volume flow (TVF) was not significantly changed (À1.0% and À13.0%, respectively). With the new protocol, the peak velocity (PV) was 49% lower than that with the conventional protocol. Thus, the new protocol has an effect of maintaining TVF without resulting in a sudden large increase or decrease in PV. Conclusion: The new suggested protocol might improve safety because it can maintain the stability of blood flow by reducing the risk of blood stasis and a rapid change in blood flow.

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Prevention of Deep Vein Thrombosis by Intermittent Pneumatic Compression of Calf

Cited by 215 publications

References 20 publications

Towards evidence-based guidelines for the prevention of venous thromboembolism: systematic reviews of mechanical methods, oral anticoagulation, dextran and regional anaesthesia as thromboprophylaxis

Towards evidence-based guidelines for the prevention of venous thromboembolism: systematic reviews of mechanical methods, oral anticoagulation, dextran and regional anaesthesia as thromboprophylaxis

Toward the individual approach to the evaluation of risks and prevention of postoperative venous thromboembolism

Investigation of Blood Flow During Intermittent Pneumatic Compression and Proposal of a New Compression Protocol

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