1993
DOI: 10.1111/j.1398-9995.1993.tb02401.x
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Prevention of pollen rhinitis symptoms: comparison of fluticasone propionate aqueous nasal spray and disodium cromoglycate aqueous nasal spray

Abstract: Fluticasone propionate aqueous spray, a new intranasal corticosteroid preparation, and disodium cromoglycate 2% aqueous nasal spray, an established preventive treatment for seasonal allergic rhinitis, were compared in a double-blind, double-dummy, parallel-group, multicentric study in France. A total of 218 patients with seasonal allergic rhinitis caused by grass pollen (verified by positive skin prick test) were preventively treated before the onset of the grass pollen season with either fluticasone propionat… Show more

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Cited by 55 publications
(21 citation statements)
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“…FPANS 200/jg once daily is as effective as BDP 200/ig twice daily in the treatment of perennial rhinitis. The effectiveness of FPANS as a once daily dosage regimen is an important factor in improving patient compliance [20]. In general.…”
Section: Discussionmentioning
confidence: 99%
“…FPANS 200/jg once daily is as effective as BDP 200/ig twice daily in the treatment of perennial rhinitis. The effectiveness of FPANS as a once daily dosage regimen is an important factor in improving patient compliance [20]. In general.…”
Section: Discussionmentioning
confidence: 99%
“…Extensive reviews of the clinical studies are available for beclomethasone dipropionate ( 98), budesonide ( 99), fluticasone propionate ( 100), mometasone furoate ( 86, 93), and triamcinolone ( 101), all agreeing on the clinical efficacy of these compounds. Other studies demonstrated that topical corticosteroids are more effective than systemic antihistamines ( 102, 103), topical antihistamines ( 104), and topical cromoglycate ( 105, 106). A recent meta‐analysis has confirmed the superiority of topical corticosteroids to antihistamines in the treatment of AR for all nasal symptoms ( 107).…”
Section: Topical Corticosteroidsmentioning
confidence: 99%
“…A modern GCS spray is definitely more effective in allergic rhinitis than sodium cromoglycate [59]. At least 14 comparative studies of topical GCS and oral antihistamines in more than 2500 patients have been published [60].…”
Section: Comparison With Other Treatmentsmentioning
confidence: 99%