Preventive action of green tea from changes in the liver antioxidant abilities of different aged rats intoxicated with ethanol

Augustyniak, Agnieszka; Waszkiewicz, Ewa; Skrzydlewska, Elżbieta

doi:10.1016/j.nut.2005.01.006

Cited by 95 publications

(54 citation statements)

References 41 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Administration of natural extracts of grape seed (Balu, Sangeetha, Haripriya, & Panneerselvam, 2005) and of green tea (Augustyniak, Waszkiewicz, & Skrzydlewska, 2005) has been reported to reduce the levels of MDA and protein carbonyls in the central nervous system and the liver of aged rats, respectively. Supplementation with antioxidant compounds such as DL-α-lipoic acid and L-carnitine has been found to reduce the concentration of MDA in aged rats (Arivazhagan, Ramanathan, & Panneerselvam, 2001;Arivazhagan, Thilakavathy, & Panneerselvam, 2000;Savitha, Tamilselvan, Anusuyadevi, & Panneerselvam, 2005).…”

Section: Inhibitory Effects On Lipid Peroxidation and Protein Carbonymentioning

confidence: 99%

In-vitro and in-vivo antioxidant effects of the oyster mushroom Pleurotus ostreatus

Jayakumar

Thomas

Sheu

et al. 2011

Food Research International

112

View full text Add to dashboard Cite

Section: Inhibitory Effects On Lipid Peroxidation and Protein Carbonymentioning

confidence: 99%

In-vitro and in-vivo antioxidant effects of the oyster mushroom Pleurotus ostreatus

Jayakumar

Thomas

Sheu

et al. 2011

Food Research International

112

View full text Add to dashboard Cite

“…ferent inducers in different organs (Hong et al, 2001;Das et al, 2002;Hiroyasu et al, 2002;Skrzydlewska et al, 2002;Zhang et al, 2002;Chen et al et al, 2004;Augustyniak et al, 2005;El-Beshbishy, 2005;Erba et al, 2005;Mohamadin et al, 2005;Sadzuka et al, 2005;Skrzydlewska et al, 2005;Yamamoto et al, 2006). Green tea suppresses reactive oxygen species (ROS) formation through polyhydroxy phenolics such as catechins that impart strong antioxidant activity.…”

Section: Figmentioning

confidence: 99%

Inhibition property of green tea extract in relation to reserpine-induced ribosomal strips of rough endoplasmic reticulum (rER) of the rat kidney proximal tubule cells

et al. 2009

View full text Add to dashboard Cite

-The aim of this study was to evaluate the effect of green tea in inhibiting and reversing the nephrotoxicity of reserpine -a potent oxidative stress inducer -which induced cellular kidney damage. Serum biochemical parameters, antioxidant enzyme levels, thiobarbituric acid reactive substances (TBARS) and serum transaminases (glutamic oxaloacetic transaminase (GOT) and glutamic pyruvic transaminase (GPT)) values and histopathology were systematically evaluated. Reserpine exposure led -ters and ultrastructural evaluation. Sprague-Dawely (S.D.) rats were intraperitonealy administered reserpine to induce oxidative kidney damage. Experimental rats were given green tea extract according to the protocol given below. Sixty rats were randomly divided into six groups, with 10 rats in each group. Reserpine was found to cause kidney proximal tubule damage, such as stripping and clustering of ribosomes from the rough endoplasmic reticulum (rER) and demolishing of mitochondrial christae with elevated level of oxidative stress markers, such as TBARS. While the ultrastructural study showed a revival of kidney proximal tubule cells as a result of the administration of green tea extract to rats. We suggest that green tea might elevate antioxidant defense system, clean up free radicals, lessen oxidative damages and protect kidney against reserpine -induced toxicity and thus had a potential protective effect.

show abstract

“…Administration of green tea partly normalized the activity of enzymes and the level of non-enzymatic antioxidants. Augustyniak et al (2005), Ji et al (1997) and Sudheer et al (2007) revealed a significant increase in the expression of cyclooxygenase-2 and NF-kB in lung and liver of nicotine-treated rats. Other factors involved in this chain reaction are reactive oxygen species (ROS) that contribute to tissue destruction in several inflammatory complications (Helieh and Theresa, 2008).…”

Section: Discussionmentioning

confidence: 91%

Role of green tea on nicotine toxicity on liver and lung of mice: Histological and morphometrical studies

Gawish¹,

Issa²,

Bassily³

et al. 2012

Afr. J. Biotechnol.

View full text Add to dashboard Cite

Nicotine is the more abundant component in cigarette smoking. The natural diet contains a variety of compounds, such as green tea that exhibit protective effects towards different toxicities. Nicotine is firstly metabolized in liver, and the lung is the main target organ susceptible to smoking; so, this study was aimed to investigate the effects of nicotine on this organs using histopathological and morphometrical methods and study the protective effect of green tea against toxicity of nicotine. Four groups of the male Swiss albino mice were used: untreated control group; nicotine-treated group (2.5 mg/kg/day); green tea-treated group (40 mg/kg./day); and nicotine and green tea intraperitoneally treated group for 28 days. The histological examinations of this study revealed a damage and degeneration in the lung and liver tissues of the nicotine treated animals. Green tea administration to nicotine-treated mice showed reduction in the tissues damage associated with the nicotine administration. Green tea administration to nicotine-treated mice ameliorated the increase in the size of nucleus of liver and restored the normal distribution of elastic fibers in lung. These results, along with previous observations, suggest that green tea may be useful in combating tissue injury that is a result of nicotine toxicity. Hence, the intake of green tea might suppress the toxicity and mutagenic activity of nicotine.

show abstract

Preventive action of green tea from changes in the liver antioxidant abilities of different aged rats intoxicated with ethanol

Cited by 95 publications

References 41 publications

In-vitro and in-vivo antioxidant effects of the oyster mushroom Pleurotus ostreatus

In-vitro and in-vivo antioxidant effects of the oyster mushroom Pleurotus ostreatus

Inhibition property of green tea extract in relation to reserpine-induced ribosomal strips of rough endoplasmic reticulum (rER) of the rat kidney proximal tubule cells

Role of green tea on nicotine toxicity on liver and lung of mice: Histological and morphometrical studies

Contact Info

Product

Resources

About