Preventive effect of selenium on chronic bacterial prostatitis

Kim, Hyun Woo; Ha, U-Syn; Woo, Jang Chun; Kim, Suk-Ju; Yoon, Byung Il; Lee, Seung‐Ju; Cho, Yong-Hyun

doi:10.1007/s10156-011-0276-4

Cited by 18 publications

(11 citation statements)

References 20 publications

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“…In several animal models, selenium status was reported to affect the immune response after bacterial infections. Combined pretreatment with selenium and the antibiotic ciprofloxacin for 4 wk was more effective than ciprofloxacin alone to prevent the development of chronic bacterial prostatitis in rats after infusion of an Escherichia coli suspension into the prostatic urethra (90). Compared with mice fed an adequate-selenium diet, seleniumdeficient mice showed a compromised response of the innate immune system after infection with the gram-positive bacterium Listeria monocytogenes (91).…”

Section: Tuberculosismentioning

confidence: 95%

Dietary Selenium in Adjuvant Therapy of Viral and Bacterial Infections

Steinbrenner¹,

Al‐Quraishy

Dkhil

et al. 2015

Advances in Nutrition

259

199

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Viral and bacterial infections are often associated with deficiencies in macronutrients and micronutrients, including the essential trace element selenium. In selenium deficiency, benign strains of Coxsackie and influenza viruses can mutate to highly pathogenic strains. Dietary supplementation to provide adequate or supranutritional selenium supply has been proposed to confer health benefits for patients suffering from some viral diseases, most notably with respect to HIV and influenza A virus (IAV) infections. In addition, selenium-containing multimicronutrient supplements improved several clinical and lifestyle variables in patients coinfected with HIV and Mycobacterium tuberculosis. Selenium status may affect the function of cells of both adaptive and innate immunity. Supranutritional selenium promotes proliferation and favors differentiation of naive CD4-positive T lymphocytes toward T helper 1 cells, thus supporting the acute cellular immune response, whereas excessive activation of the immune system and ensuing host tissue damage are counteracted through directing macrophages toward the M2 phenotype. This review provides an up-to-date overview on selenium in infectious diseases caused by viruses (e.g., HIV, IAV, hepatitis C virus, poliovirus, West Nile virus) and bacteria (e.g., M. tuberculosis, Helicobacter pylori). Data from epidemiologic studies and intervention trials, with selenium alone or in combination with other micronutrients, and animal experiments are discussed against the background of dietary selenium requirements to alter immune functions.

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Section: Tuberculosismentioning

confidence: 95%

Dietary Selenium in Adjuvant Therapy of Viral and Bacterial Infections

Steinbrenner¹,

Al‐Quraishy

Dkhil

et al. 2015

Advances in Nutrition

259

199

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“…The capacity of these bacteria to form biofilms containing antibiotic persistent bacteria explains recurrent CBP [ 111 , 113 , 114 ]. The rat model has been extensively used to demonstrate the importance of virulence factors or quorum sensing systems in CBP [ 115 , 116 , 117 ]. This model was also used to evaluate therapeutic strategies against E. coli- induced CBP using catechin, ciprofloxacin, or cranberry [ 118 , 119 ] as well as the potential of selenium in combination with ciprofloxacin [ 115 ].…”

Section: Tissue-associated Biofilm Modelsmentioning

confidence: 99%

From in vitro to in vivo Models of Bacterial Biofilm-Related Infections

et al. 2013

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The influence of microorganisms growing as sessile communities in a large number of human infections has been extensively studied and recognized for 30–40 years, therefore warranting intense scientific and medical research. Nonetheless, mimicking the biofilm-life style of bacteria and biofilm-related infections has been an arduous task. Models used to study biofilms range from simple in vitro to complex in vivo models of tissues or device-related infections. These different models have progressively contributed to the current knowledge of biofilm physiology within the host context. While far from a complete understanding of the multiple elements controlling the dynamic interactions between the host and biofilms, we are nowadays witnessing the emergence of promising preventive or curative strategies to fight biofilm-related infections. This review undertakes a comprehensive analysis of the literature from a historic perspective commenting on the contribution of the different models and discussing future venues and new approaches that can be merged with more traditional techniques in order to model biofilm-infections and efficiently fight them.

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“…Too low or too high intake of Se leads to formation of various disturbances in organism. Moderate deficit of this element increases the risk of infertility in men, nephropathy, prostate cancer, the occurrence of neurological diseases, ischemic heart disease, and endemic osteoarthropathy (Kashin-Beck disease), impair functioning of immune system and may lead to susceptibility to bacterial and viral infection [4][5][6][7][8][9]. However, in the case of over-supply, Se becomes toxic and may increase the risk of brain disorders, endocrine system disruption and cancer [10].…”

Section: Introductionmentioning

confidence: 99%

Selenium Anticancer Properties and Impact on Cellular Redox Status

et al. 2020

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(1) Background: In this review, we provide information published in recent years on the chemical forms, main biological functions and especially on antioxidant and prooxidant activities of selenium. The main focus is put on the impact of selenoproteins on maintaining cellular redox balance and anticancerogenic function. Moreover, we summarize data on chemotherapeutic application of redox active selenium compounds. (2) Methods: In the first section, main aspects of metabolism and redox activity of selenium compounds is reviewed. The second outlines multiple biological functions, asserted when selenium is incorporated into the structure of selenoproteins. The final section focuses on anticancer activity of selenium and chemotherapeutic application of redox active selenium compounds as well. (3) Results: optimal dietary level of selenium ensures its proper antioxidant and anticancer activity. We pay special attention to antioxidant activities of selenium compounds, especially selenoproteins, and their importance in antioxidant defence. It is worth noting, that data on selenium anticancer properties is still contraversive. Moreover, selenium compounds as chemotherapeutic agents usually are used at supranutritional doses. (4) Conclusions: Selenium play a vital role for many organism systems due to its incorporation into selenoproteins structure. Selenium possesses antioxidant activity at optimal doses, while at supranutritional doses, it displays prooxidant activity. Redox active selenium compounds can be used for cancer treatment; recently special attention is put to selenium containing nanoparticles.

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Preventive effect of selenium on chronic bacterial prostatitis

Cited by 18 publications

References 20 publications

Dietary Selenium in Adjuvant Therapy of Viral and Bacterial Infections

Dietary Selenium in Adjuvant Therapy of Viral and Bacterial Infections

From in vitro to in vivo Models of Bacterial Biofilm-Related Infections

Selenium Anticancer Properties and Impact on Cellular Redox Status

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