Preventive Treatments of Iron Deficiency Anaemia in Pregnancy: A Review of Their Effectiveness and Implications for Health System Strengthening

Osungbade, Kayode O.; Oladunjoye, Adeolu O

doi:10.1155/2012/454601

Cited by 41 publications

(37 citation statements)

References 42 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Anemia is one of the most common nutritional deficiency disorders in the world [6]. The World Health Organization (WHO) defines iron deficiency anemia (IDA) as anemia accompanied by depleted iron stores and signs of a compromised supply of iron to the tissues [7,8]. …”

Section: Introductionmentioning

confidence: 99%

Red blood cell distribution width and iron deficiency anemia among pregnant Sudanese women

Abdelrahman¹,

Gasim

Musa

et al. 2012

Diagn Pathol

View full text Add to dashboard Cite

BackgroundIron deficiency anemia (IDA) is a major health problem during pregnancy and it has adverse effects on the mother and the newborn. Red cell distribution width (RDW), which is a quantitative measure for red cell size variation (anisocytosis), is a predictor of IDA. Little is known regarding RDW and IDA during pregnancy.MethodsA cross sectional study was conducted at the antenatal clinic of Khartoum Hospital, Sudan, to determine the performance of RDW in the diagnosis of IDA using serum ferritin as a gold standard.ResultsAmong 194 pregnant women with a gestational period of 21.4 ± 6.5 weeks, 57 (29.4%) had IDA according to serum ferritin levels (<15 μg/l) and 61 (31.4%) had IDA according to RDW (>14.5). The sensitivity, specificity, positive predictive value, and negative predictive value of RDW where serum ferritin was the gold standard were 43.8% (95% CI: 31.4–57.0%), 73.7% (95% CI: 65.8–80.5%), 41.0% (95% CI: 29.2–53.6%), and 76.0% (95% CI: 68.1–82.6%), respectively.ConclusionsIn this study, we found that RDW has a poor performance in diagnosing IDA among pregnant women compared with serum ferritin as the gold standard.Virtual slidesThe virtual slides for this article can be found here: http://www.diagnosticpathology.diagnomx.eu/vs/1721072967826303

show abstract

Section: Introductionmentioning

confidence: 99%

Red blood cell distribution width and iron deficiency anemia among pregnant Sudanese women

Abdelrahman¹,

Gasim

Musa

et al. 2012

Diagn Pathol

View full text Add to dashboard Cite

show abstract

“…PENDAHULUAN Anemia defisiensi zat besi merupakan defisiensi zat gizi yang paling banyak di dunia. Anemia defisiensi besi didefinisikan sebagai anemia karena habisnya cadangan besi dalam jaringan (Osungbade 2012). Di Indonesia, prevalensi anemia pada anak usia ≥1 tahun sebesar 21,7%, pada balita 12-59 bulan sebesar 28,1%, dan ibu hamil sebesar 37,1% (Kemenkes 2013).…”

Section: J Giziunclassified

Fortifikasi NaFeEDTA pada cookies ubi jalar kuning sebagai produk alternatif untuk menanggulangi anemia defisiensi besi

2017

View full text Add to dashboard Cite

The aims of the study were to analyze iron content, beta carotene content and organoleptic test of orange fleshed sweet potato cookies which had been fortified with NaFeEDTA. This reaserch used experimental method with one factor completely randomized design of iron with 100 ppm, 150 ppm and 200 ppm of NaFeEDTA. Analysis of iron content was conducted using Atomic Absorption Spectrophotometry and analysis of beta carotene was conducted by using spectrophotometry. Then, organoleptic test was conducted using hedonic test. The result of iron content in cookies is 27.97 ppm-53.42 ppm while beta caroten is 83.40 ppm-129.72 ppm. Organoleptic test results in terms of color, aroma, and texture, the fortified cookies were as well-liked as the control ones; taste, however, the panel found the fortified cookies more preferable. The highest level of iron content, beta carotene content and organoleptic test were orange fleshed sweet potato cookies fortified with 200 ppm NaFeEDTA.

show abstract

“…Heme iron remains in the porphyrin complex until it is absorbed by the mucosal cells; the influence of external factors on heme iron absorption is minimal. However, non-heme iron absorption is influenced by factors that enhance or inhibit iron solubility (Osungbade and Oladunjoye, 2012).…”

Section: Dietary Sources and Iron Metabolismmentioning

confidence: 99%

Challenges and strategies to combat global iron deficiency by food fortification

2016

View full text Add to dashboard Cite

Iron is an important micronutrient required for healthy living. Therefore, populations dependent primarily on plant-based diets with little or no animal flesh may become deficient in iron. It is found that ~ 30% of the world population suffers from iron deficiency anemia. Since iron undergoes oxidation which reduces its absorption, formulation of iron supplements and fortificants for treatment of iron deficiency has been studied extensively. Iron fortified food has been introduced in order to overcome the iron deficiency. Chelation of iron with amino acids, EDTA, fumarate, succinate, and gluconate and encapsulating iron by inclusion complexation and liposome encapsulations have improved the bioavailability of iron in the human body. Among these methods, iron delivery via complexation andencapsulation are common due to their high efficacy and simplicity.

show abstract

Preventive Treatments of Iron Deficiency Anaemia in Pregnancy: A Review of Their Effectiveness and Implications for Health System Strengthening

Cited by 41 publications

References 42 publications

Red blood cell distribution width and iron deficiency anemia among pregnant Sudanese women

Red blood cell distribution width and iron deficiency anemia among pregnant Sudanese women

Fortifikasi NaFeEDTA pada cookies ubi jalar kuning sebagai produk alternatif untuk menanggulangi anemia defisiensi besi

Challenges and strategies to combat global iron deficiency by food fortification

Contact Info

Product

Resources

About