Priapism: A rare presentation of precursor B-Cell acute lymphoblastic leukemia

Güzelküçük, Zeliha; Kaçar, Dilek; Demir, Rabia; Kürtül, Meltem; Yaralı, Hüsniye Neşe; Özbek, Namık

doi:10.24953/turkjped.2019.02.029

Cited by 3 publications

(4 citation statements)

References 6 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Chang et al have described priapism secondary to acute myeloid leukemia due to the direct penetration of the penis by leukemia cells [ 8 ]. As in most of the reports described [ 9 – 17 ], hyperleukocytosis was the most likely cause of priapism in the two cases of this report.…”

Section: Discussionsupporting

confidence: 79%

“…To date, less than 20 cases of priapism and chronic myeloid leukemia [2,3,5,[8][9][10][11][12][13][14][15] have been reported and 2 cases of priapism and acute lymphoblastic leukemia [16,17] (Table 1).…”

Section: Discussionmentioning

confidence: 99%

“…The review showed that corporal aspiration/irrigation or a distal shunt was sufficient in achieving at least partial detumescence [2,5,8]. These procedures were followed by the treatment of the underlying leukemia with adequate hydration, hydroxyurea, imatinib, and leukapheresis [10][11][12][13][14][15][16][17]. The reports showed disease remission at a maximum 6-month follow-up with adequate erectile function.…”

Section: Discussionmentioning

confidence: 99%

See 2 more Smart Citations

Unusual Presentation of Priapism Associated with Acute and Chronic Myeloid Leukemia in Two Patients: Emergency Management

Gaye

Thiam

Cassell

et al. 2020

Case Reports in Urology

View full text Add to dashboard Cite

Priapism is a rare urological emergency. It is rarely a telltale sign of myeloid leukemia. We report two cases of acute myeloid leukemia in a child and chronic myeloid leukemia in a young adult presenting with priapism. Puncture irrigation of the corpora cavernosa followed by systemic treatment to lower the hyperviscosity of the blood due to leukemia provided optimal outcome. Prompt emergency management is required to lower the complication of erectile dysfunction.

show abstract

Section: Discussionsupporting

confidence: 79%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Unusual Presentation of Priapism Associated with Acute and Chronic Myeloid Leukemia in Two Patients: Emergency Management

Gaye

Thiam

Cassell

et al. 2020

Case Reports in Urology

View full text Add to dashboard Cite

show abstract

“…The most common cause of priapism in children is sickle cell disease (65%), followed by leukemia (10%), trauma (10%), an idiopathic cause (10%), and a pharmacologically induced cause (5%). Its association with leukemia, particularly acute lymphoblastic leukemia (ALL), is a distinct and infrequently reported phenomenon [ 2 ]. Understanding the mechanism of priapism in the setting of leukemia and formulating an effective multidisciplinary approach to its management is paramount for providing optimal care to affected pediatric patients.…”

Section: Introductionmentioning

confidence: 99%

Priapism as an Unusual Symptom of T-cell Acute Lymphoblastic Leukemia in a Pediatric Case

Mustafa,

Hanafy,

Riyad

et al. 2024

Cureus

View full text Add to dashboard Cite

Acute lymphoblastic leukemia (ALL) in pediatric patients typically presents with recognizable symptoms such as fever, pallor, and bone pain. However, atypical manifestations can complicate the diagnostic landscape. We present a unique case of a seven-year-old male with T-cell ALL whose presenting symptom was priapism. This case underscores the need for heightened awareness among healthcare professionals regarding the diverse clinical presentations of leukemia, emphasizing the importance of a multidisciplinary team approach for comprehensive evaluation and management. Our seven-year-old patient presented with priapism. A comprehensive diagnostic workup, including complete blood counts and subsequent bone marrow examination, led to the diagnosis of T-cell ALL. Given the rare presentation, a multidisciplinary team consisting of pediatric oncologists/hematologists, urologists, and other relevant specialists collaborated to formulate a tailored treatment plan. The patient received an intensified chemotherapy regimen, resulting in the resolution of priapism and hematologic improvement. Priapism as an initial presentation of T-cell ALL in a pediatric patient is an exceptional occurrence, necessitating a specialized and collaborative approach to diagnosis and management. This case report highlights the importance of interdisciplinary coordination involving pediatric oncologists and urologists in addressing the unique challenges posed by atypical leukemia presentations. The rarity of this manifestation emphasizes the need for further research to elucidate the underlying mechanisms and establish optimal management strategies for similar cases.

show abstract

Epidural blockade for alternative management of priapism: A case report of child with T-cell acute lymphoblastic leukemia

Gökçe

Gül

Orhan

et al. 2021

Urology

View full text Add to dashboard Cite

Priapism: A rare presentation of precursor B-Cell acute lymphoblastic leukemia

Cited by 3 publications

References 6 publications

Unusual Presentation of Priapism Associated with Acute and Chronic Myeloid Leukemia in Two Patients: Emergency Management

Unusual Presentation of Priapism Associated with Acute and Chronic Myeloid Leukemia in Two Patients: Emergency Management

Priapism as an Unusual Symptom of T-cell Acute Lymphoblastic Leukemia in a Pediatric Case

Epidural blockade for alternative management of priapism: A case report of child with T-cell acute lymphoblastic leukemia

Contact Info

Product

Resources

About