Priapism in patients with hemolytic disorders: a nationwide retrospective cohort study

Tranekær, Stinne; Hansen, Dennis Lund; Biemond, Bart J.; Sørensen, Anne; Glenthøj, Andreas; Petersen, Jesper; Frederiksen, Henrik

doi:10.1007/s00277-021-04577-x

Cited by 5 publications

(2 citation statements)

References 26 publications

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“…Priapism is a genitourinary emergency condition and clarified as unrationalized prolonged penile erection, complete or partial penile tumescence lasting for more than or equal to four hours without sexual arousal or desire (1) . Globally, priapism was dramatically reported with increased prevalence and there is a time-dependent relationship between the total duration of erection and increasing risk of permanent erectile dysfunction (2) . There is a bimodal peak distribution of prevalence at the hospital from 2010 to 2021 (3) .…”

Section: Introductionmentioning

confidence: 99%

The Effectiveness of Priapism's Structured Educational Module on Nurses' Knowledge, Attitude, Beliefs, and Patient’s Profile

Elbqry

Ibrahim

Sherif

et al. 2022

Tanta Scientific Nursing Journal

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Section: Introductionmentioning

confidence: 99%

The Effectiveness of Priapism's Structured Educational Module on Nurses' Knowledge, Attitude, Beliefs, and Patient’s Profile

Elbqry

Ibrahim

Sherif

et al. 2022

Tanta Scientific Nursing Journal

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“…1,2 While the etiology is idiopathic in over a third of cases, certain conditions such as blood dyscrasias (eg, sickle cell disease [SCD]) or cancer (eg, leukemia, multiple myeloma, metastatic cancer) are known risk factors. [3][4][5] The sexual sequelae of priapism are well known and include erectile dysfunction (ED), penile fibrosis, and recurrent priapism. [6][7][8][9] While priapism has been associated with known health conditions, other sequelae for men diagnosed with priapism are unknown.…”

mentioning

confidence: 99%

The Risk of Cardiovascular and Cerebrovascular Disease in Men With a History of Priapism

Mulloy

Belladelli

et al. 2023

Journal of Urology

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Purpose: Priapism is a debilitating condition that affects sexual function. As a majority of cases are idiopathic, investigators have hypothesized underlying vascular dysfunction which may predispose men to priapism. We sought to determine if men are at risk for other sequelae of vascular dysfunction such as cardiovascular and thromboembolic disease after a priapism event. Materials and Methods: Using a large commercial insurance claims data warehouse, we evaluated all men (age 20) with a diagnosis of priapism from 2003-2020 and matched them to a cohort of men with other urological disorders of sexual dysfunction (erectile dysfunction, Peyronie's disease, and premature ejaculation). We identified incident disease (cardiovascular disease, heart disease, embolism, thrombosis, cerebrovascular disease) for all cohorts. Results: A total of 10,459 men with priapism were identified and were matched to men with erectile dysfunction, Peyronie's disease, or premature ejaculation. The mean age was 51.1 years old. Men with priapism showed increased incidence of heart disease, both ischemic (HR 1.24, 95% CI 1.09-1.42) and other heart disease (HR 1.24, 95% CI 1.12-1.38) in the years following the priapism diagnosis. Incident cerebrovascular disease was also more likely in men with a history of priapism (HR 1.33,. Men requiring treatment for ischemic priapism had a higher hazard of cardiovascular and cerebrovascular disease. In addition, men with more priapism episodes had a higher rate of cardiovascular disease and thromboembolic events. Conclusions: Men with priapism are at increased risk for cardiovascular and cerebrovascular events in the years following a priapism.

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Trends and outcomes of hospitalized patients with priapism in Germany: results from the GRAND study

Pyrgidis,

Schulz,

Chaloupka

et al. 2024

Int J Impot Res

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We aimed to provide evidence on the trends and in-hospital outcomes of patients with low- and high-flow priapism through the largest study in the field. We used the GeRmAn Nationwide inpatient Data (GRAND), provided by the Research Data Center of the Federal Bureau of Statistics (2008-2021), and performed multiple patient-level analyses. We included 6,588 men with low-flow and 729 with high-flow priapism. Among patients with low-flow priapism, 156 (2.4%) suffered from sickle cell disease, and 1,477 (22.4%) patients required shunt surgery. Of them, only 37 (2.5%) received a concomitant penile prosthesis implantation (30 inflatable and 7 semi-rigid prosthesis). In Germany, the total number of patients with low-flow priapism requiring hospital stay has steadily increased, while the number of patients with high-flow priapism requiring hospital stay has decreased in the last years. Among patients with high-flow priapism, 136 (18.7%) required selective artery embolization. In men with low-flow priapism, sickle cell disease was associated with high rates of exchange transfusion (OR: 21, 95% CI: 14–31, p < 0.001). The length of hospital stay (p = 0.06) and the intensive care unit admissions (p = 0.9) did not differ between patients with low-flow priapism due to sickle cell disease versus other causes of low-flow priapism. Accordingly, in men with high-flow priapism, embolization was not associated with worse outcomes in terms of length of hospital stay (p > 0.9), transfusion (p = 0.8), and intensive care unit admission (p = 0.5). Low-flow priapism is an absolute emergency that requires shunt surgery in more than one-fifth of all patients requiring hospital stay. On the contrary, high-flow priapism is still managed, in most cases, conservatively.

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Priapism in patients with hemolytic disorders: a nationwide retrospective cohort study

Cited by 5 publications

References 26 publications

The Effectiveness of Priapism's Structured Educational Module on Nurses' Knowledge, Attitude, Beliefs, and Patient’s Profile

The Effectiveness of Priapism's Structured Educational Module on Nurses' Knowledge, Attitude, Beliefs, and Patient’s Profile

The Risk of Cardiovascular and Cerebrovascular Disease in Men With a History of Priapism

Trends and outcomes of hospitalized patients with priapism in Germany: results from the GRAND study

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