Primary Angiosarcoma of the Breast: A Single-Center Retrospective Study in Korea

Kim, Yeon-Jin; Ryu, Jai-Min; Lee, Se-Kyung; Chae, Byung Joo; Kim, Seok-Won; Nam, Seok‐Jin; Yu, Jonghan; Lee, Jeong-Eon

doi:10.3390/curroncol29050267

Cited by 12 publications

(5 citation statements)

References 24 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Studies show that larger tumour size and higher grade are associated with an increased risk of local recurrence and reduced overall survival. 26 …”

Section: Discussionmentioning

confidence: 99%

Primary angiosarcoma of the breast in a 21-year-old female: A case report

Wijetilake,

Senavirathna,

Wijesinghe

et al. 2024

SAGE Open Medical Case Reports

View full text Add to dashboard Cite

We present a case of primary angiosarcoma, an exceedingly rare malignant breast lesion, in a 21-year-old female patient with unilateral breast enlargement. Primary angiosarcoma is an aggressive form of breast cancer with variable presentation and limited clinical experience due to the rarity of the disease. Despite an initial diagnostic challenge, this report showcases the importance of a systematic diagnostic approach and multidisciplinary management in the context of uncommon breast lesions in young patients. Our patient underwent a mastectomy followed by breast reconstruction, achieving favourable cosmetic outcomes. This case serves as a contribution to our understanding of the diagnostic considerations surrounding angiosarcoma of the breast in a young patient.

show abstract

“…Studies show that larger tumour size and higher grade are associated with an increased risk of local recurrence and reduced overall survival. 26 …”

Section: Discussionmentioning

confidence: 99%

Primary angiosarcoma of the breast in a 21-year-old female: A case report

Wijetilake,

Senavirathna,

Wijesinghe

et al. 2024

SAGE Open Medical Case Reports

View full text Add to dashboard Cite

show abstract

“…Surgical resection is the primary treatment for angiosarcoma of the breast, which often involves mastectomy with the removal of all irradiated tissue [5]. However, angiosarcoma can present as a multifocal lesion, so it can be challenging to achieve complete resection with clear margins.…”

Section: Discussionmentioning

confidence: 99%

Breast Angiosarcoma Case Report

2024

J Oncol Res Ther

View full text Add to dashboard Cite

We present a case of a 77-year-old female who was diagnosed with right breast invasive carcinoma treated with breastconserving surgery and adjuvant radiation therapy in 2015. In 2023, she was diagnosed with radiation-induced angiosarcoma (RIAS), and a right breast mastectomy was recommended. RIAS is difficult to diagnose due to its rarity and non-specific symptoms. This paper examines various factors causing RIAS and strategies to manage this disease. Even though achieving clear margins is challenging due to its multifocal nature, surgical resection remains the primary treatment for RIAS. The role of chemotherapy remains unclear, although targeted therapies may offer alternative options. The prognosis for RIAS is influenced by factors including the size of the tumor and stage at diagnosis. Adjuvant chemotherapy's role is still evolving, and developments within radiotherapy approaches have allowed for enhanced local control. Further research is required to develop optimal treatment protocols and preventive strategies.

show abstract

“…The prognosis of PBA is very poor, and patients undergoing surgery at the earliest may prolong the life ( 9 ). Abdou concluded that tumor size and grade are reliable predictors of prognosis, and survival is significantly lower for high-grade tumors or those spanning greater than 5 cm ( 3 , 10 ). However, Alessandra concluded that grade does not affect prognosis ( 11 ).…”

Section: Discussionmentioning

confidence: 99%

A case report of primary angiosarcoma of the breast

Huang¹,

Xian²,

Zhou³

et al. 2023

Transl Cancer Res

View full text Add to dashboard Cite

Background: Breast Angiosarcoma can be divided into primary breast angiosarcoma (PBA) and second breast angiosarcoma (SBA). PBA is rare malignant breast cancer with poor outcomes. PBA usually occurs in women between 30-40 years old. PBA does not have a specific clinical manifestation. Clinically, PBA presents with a rapidly enlarging breast mass and skin involvement with skin color changes. Ultrasonography of PBA can be hypoechoic or hyperechoic, or mixed disordered areas. Microscopically, PBA can be classified into three grades according to the degree of differentiation, and the grade is related to the prognosis. And PBA can also express vascular endothelial markers. The main treatment for PBA is surgery, especially mastectomy. There are other treatments, such as chemotherapy and radiotherapy, but their effectiveness needs further confirmation. Targeted drugs may be helpful.Case Description: A 32-year-old woman with main clinical presentation of a rapidly growing mass located in the upper inner quadrant of the right breast with skin involvement. PBA was diagnosed with first extended local resection, and then the patient underwent a second right mastectomy. The patient is now undergoing chemotherapy.Conclusions: Since this is a rare form of breast cancer, we report this case to raise the attention of breast surgeons to avoid misdiagnoses.

show abstract

Primary Angiosarcoma of the Breast: A Single-Center Retrospective Study in Korea

Cited by 12 publications

References 24 publications

Primary angiosarcoma of the breast in a 21-year-old female: A case report

Primary angiosarcoma of the breast in a 21-year-old female: A case report

Breast Angiosarcoma Case Report

A case report of primary angiosarcoma of the breast

Contact Info

Product

Resources

About