Primary Anorectal Malignant Melanoma: Two Case Reports and Review of the Literature

Biyikoglu, Ibrahim; Öztürk, Zeynel Abidin; Köklü, Seyfettin; Babali, Aysegul; Akay, Hatice; Filik, Levent; Basat, Osman; Özer, Hilal; Ozer, Elif Comert

doi:10.3816/ccc.2007.n.020

Cited by 7 publications

(2 citation statements)

References 32 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…One reason is that AMM usually presents as a polypoidal lesion projecting into the anorectal lumen and locates in the dentate line, which is always misdiagnosed as hemorrhoids and polyp (Heyn et al 2007;Ceccopieri et al 2000;Biyikoglu et al 2007;Felz et al 2001), thus making the treatment diYcult. Since misdiagnosis often causes a delay of timely treatment, to elucidate the eVect of misdiagnosis on AMM's prognosis is important.…”

Section: Introductionmentioning

confidence: 99%

Effect of misdiagnosis on the prognosis of anorectal malignant melanoma

Zhang

Gao

Wan

2010

J Cancer Res Clin Oncol

View full text Add to dashboard Cite

show abstract

Section: Introductionmentioning

confidence: 99%

Effect of misdiagnosis on the prognosis of anorectal malignant melanoma

Zhang

Gao

Wan

2010

J Cancer Res Clin Oncol

View full text Add to dashboard Cite

show abstract

“…At the time of diagnosis, 61% of patients have local regional lymph node metastases, and 21% have distant metastases [4]. It comes as no surprise that the mean survival after diagnosis is 15–25 months [5]. Furthermore, the presenting symptoms are usually non-specific and include bleeding, tenesmus, pruritus, pain, and change in bowel habits.…”

Section: Introductionmentioning

confidence: 99%

Endobronchial metastasis from primary anorectal melanoma

et al. 2013

View full text Add to dashboard Cite

Patient: Male, 64Final Diagnosis: Metastatic anorectal melanoma with endotracheal metastasisSymptoms: Fatigue • weight loss • hematochezia • coughMedication: NoneClinical Procedure: Biopsy of anal mass • rigid bronchoscopySpecialty: Internal medicine • oncology • pulmonologyObjective:Rare diseaseBackground:Anorectal melanoma is a rare cancer with a poor prognosis. The mean survival after diagnosis is 15–25 months. At the time of diagnosis, 61% of patients have local regional lymph node metastases, and 21% have distant metastases. The lungs are a common site for metastasis for all tumors including melanoma. However endobronchial metastasis is a rare phenomenon. Endotracheal metastases are even rarer, occurring in only 5% of patients with extrapulmonary endobronchial metastases. It is most commonly seen in breast, colorectal, and kidney cancers. It is extremely rare for cutaneous melanoma. The mean survival after diagnosis is only 15 months and treatment options are limited.Case Report:We report the case of a 64 year-old gentleman with newly diagnosed metastatic anorectal melanoma. A 3 cm by 3 cm bluish-black, oval-shaped, exophytic mass protruding from his anus was found on physical exam. Endobronchial and endotracheal metastasis to the trachea were discovered on computed tomography and he was subsequently taken to the operating room for argon plasma coagulation laser recanalization of his trachea via rigid bronchoscopy, and resection of his anal mass.Conclusions:We have presented the first known case of anorectal melanoma with endobronchial metastasis. Palliative APC laser recanalization was used to prevent asphyxiation from the endotracheal mass. Endobronchial metastasis is uncommon and can be easily mistaken for primary bronchogenic carcinoma. It should always be considered when evaluating patients with new lung masses.

show abstract