Primary Bone Tumors of the Skull: Spectrum of 125 Cases, with Review of Literature

Kakkar, Aanchal; Nambirajan, Aruna; Suri, Vaishali; Sarkar, Chitra; Kale, Shashank Sharad; Singh, Meharban; Sharma, Mehar Chand

doi:10.1055/s-0035-1570347

Cited by 27 publications

(15 citation statements)

References 28 publications

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“…The most common benign skull bone tumor, 14 osteoma, is a slow-growing osteogenic lesion typically composed of well-differentiated mature bone tissue. To surgically remove the hard tissue as well as keep the cosmetic profile would be of great challenge.…”

Section: Discussionmentioning

confidence: 99%

Printing a patient-specific instrument guide for skull osteoma management

Wang

Huang

et al. 2020

Journal of the Chinese Medical Association

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Background: To surgically remove osteoma and to keep an optimal cosmetic profile would be very challenging. To solve the difficulty, we utilized the three-dimensional (3D) printing technologies in generating a patient-specific instrument guide (PSIG) for the safe removal of a skull bone tumor. Methods: The preoperational brain computed tomography (CT) provided the digital imaging with thin slices, and then images were reconstructed into a 3D skull model. Based on the model, we designed a PSIG to make landmarks on the osteoma to avoid excessive removal of the skull bone. During the operation, the surgeons could remove the osteoma piece by piece by using the landmark as a reference point. Results: The PSIG was successfully applied to remove an osteoma that measured 60 × 48 × 40 mm 3 over the left frontoparietal skull of a female patient. The 3D CT reconstruction taken both before and 4 months after surgery showed a significant change in the appearance of the osteoma. Conclusion: The PSIG was able to guide the surgeon in the safe removal of the skull osteoma, as well as in maintaining the cosmetic skull profile.

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Section: Discussionmentioning

confidence: 99%

Printing a patient-specific instrument guide for skull osteoma management

Wang

Huang

et al. 2020

Journal of the Chinese Medical Association

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“…Of these, malignant tumors (78.4%) were more common than benign (14.4%), chordoma was the most common neoplasm (34.4%), and base of the skull was the most frequent location. [ 1 ]…”

Section: Discussionmentioning

confidence: 99%

“…Chondrosarcomas are rare neoplasms accounting for only 0.16% of all intracranial tumors, and majority of these occur at the base of the skull (petrous temporal bone, clivus, and temporo-occipital junction). [ 1 ] There were three cases of cranial chondrosarcomas with similar sites of occurrence. Spinal chondrosarcomas are rare and represent <10% of all chondrosarcomas.…”

Section: Discussionmentioning

confidence: 99%

“…Among GCTs of the bone, approximately 1% affects the bones of the skull and face, with the sphenoid bone being the most common location. [ 1 ] GCT of the spine is rare and is among the aggressive benign primary tumors of the spine, with a high predilection for recurrences. We identified two cases of GCT: one involving the clivus and the other C7 vertebra.…”

Section: Discussionmentioning

confidence: 99%

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Bony lesions of cranium and spine: A study of 123 cases

Kolhe

Shenoy

Laul

et al. 2020

J Craniovert Jun Spine

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Context: Bony lesions involving the cranium and spine have a wide range of etiologies, ranging from congenital, traumatic, inflammatory, to neoplastic. Aim: The aim was to analyze the histological spectrum of various bony lesions of cranium and spine received as biopsies from the neurosurgery department in our hospital. Materials and Methods: There were 123 cases of bony lesions of cranium and spine diagnosed over a period of 5 years during 2015–2019 in the neuropathology laboratory. These cases were studied retrospectively. Results: Out of the total 123 cases of bony lesions analyzed, 75 affected the cranium and 48 affected the spine. Overall, neoplastic lesions (83) were more frequent than the nonneoplastic lesions (40). In the cranium, neoplastic lesions (66/75) outnumbered the nonneoplastic ones (9/75), whereas in the spine, nonneoplastic lesions (31/48) were more common. Chordoma (40/83) was the most common neoplasm, whereas tuberculous osteomyelitis (30/40) was the most common nonneoplastic lesion encountered. Majority of the patients were adult males aged between 21 and 50 years. Rare lesions such as spinal osteochondroma, poorly differentiated neoplasm metastatic to the cervical spine from a primary salivary gland neoplasm, spinal metastasis of a glioblastoma, and intraosseous meningioma of cranium were recorded. Conclusions: The study provides epidemiological information regarding the incidence and nature of bone lesions of the spine and cranium.

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“…11 Factors complicating these reconstructions include a history of radiation therapy, preexisting scar formation, underlying compromise of the immune system (secondary to the use of steroids), and prior surgical intervention. 4 This article reports our experience with complex, solitary calvarial tumors involving en bloc resection followed by "duraplasty, cranioplasty, and soft tissue" reconstruction. We developed a novel algorithm for a "three-layered" closure technique for complex lesions with dural, skull, and scalp involvement, presenting two illustrative cases.…”

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confidence: 99%

En bloc Resection of Solitary Cranial Tumors: An Algorithmic Reconstructive Approach

Egeler

Johnson

et al. 2019

J Reconstr Microsurg Open

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Background This study analyzes the surgical outcomes for single setting surgeries involving en-bloc solitary calvarial tumor resection in combination with three-layered reconstruction, presenting a novel planning algorithm. Methods Data were retrieved for all patients undergoing single-stage tumor excision, using our novel three-layered reconstructive approach (duraplasty, cranioplasty, and soft tissue reconstruction) between 2005 and 2017 at a single tertiary hospital center. Patients ≥18 years with a Karnofsky Performance score (KPS) >70 and a life expectancy of > 2 months were included. Patient characteristics, surgical specifics, histological diagnoses, outcomes, and complications were reviewed. Results Eighteen single-staged excisions and three-layered reconstructions were performed. Seven patients presented with primary tumors and 11 patients with metastases. Mean age was 62 years. Mean follow-up time was 39 months. Primary closure was used in 12 of 18 patients, microvascular free flap with skin grafting in 4 of 18, and local advancement or rotational flap in 2 of 18. Two compromised free flaps were revised. There was no flap necrosis, skin graft failure, or wound infection observed in this series. Neurosurgical complications included two cases with seizures, one sublesional intraparenchymal hematoma, one adjacent parenchymal infarct, one case of delayed postradiation cerebrospinal fluid leakage, and one case of subdural hemorrhage. Conclusion En-bloc excision followed by three-layered reconstruction is a feasible and often suitable single-stage technique for complex solitary metastasis or primary calvarial tumors, which historically have been challenging to treat. It can offer an alternative approach to primary and metastatic calvarial tumors other than palliative treatment or hospice care.

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Primary Bone Tumors of the Skull: Spectrum of 125 Cases, with Review of Literature

Abstract: This is the largest series of primary skull bone tumors from India. Documentation of such a series will aid in approaching differential diagnosis of skull tumors in a systematic manner.

Cited by 27 publications

References 28 publications

Printing a patient-specific instrument guide for skull osteoma management

Printing a patient-specific instrument guide for skull osteoma management

Bony lesions of cranium and spine: A study of 123 cases

En bloc Resection of Solitary Cranial Tumors: An Algorithmic Reconstructive Approach

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