Primary Cardiac Leiomyosarcoma Growing Rapidly and Causing Right Ventricular Outflow Obstruction.

Abstract

Leiomyosarcomasare extremely rare primary cardiac tumors. Wereport a rapidly growing primary leiomyosarcoma of the right ventricle, which obstructed the right ventricular outflow tract within one monthafter symptomonset in a 68-year-old man. Two-dimensionalechocardiography was useful in diagnosing the extent and progression of the tumor. The tumor was surgically resected on an emergency basis, and the right ventricle and pulmonary artery were successfully reconstructed. Recurrence of the tumor on the right ventricle was observed, and the patient was overcomeby sudden dyspnea and died three monthsafter surgery.

Cardiac angiosarcoma: Too little known, too late treatment or just too bad a tumour?

“…Until recently, the results of surgery alone have been poor. Of the reported cases where surgery has been the sole form of therapy, postoperative survival ranged from 5 days to 9 months 5–11 . Survival following chemotherapy and/or radiation therapy alone ranges from 3 to 12 months 12,13 .…”

Rapidly Growing Primary Cardiac Leiomyosarcoma: Report of a Case

“…4 Only 38 cases of cardiac leiomyosarcomas have been reported, including 7 cases in Japan. 5 Half of all such leiomyosarcomas are located in the left atrium. The mean patient age for leiomyosarcomas is about 45 years (range 6 weeks-77 years).…”

“…The mean patient age for leiomyosarcomas is about 45 years (range 6 weeks-77 years). 5 Leiomyosarcomas are twice as common in females as in males. 1,5 The clinical presentation of leiomyosarcoma is nonspecific.…”

“…5 Leiomyosarcomas are twice as common in females as in males. 1,5 The clinical presentation of leiomyosarcoma is nonspecific. Most common symptoms can be attributed to congestive heart failure and the most common symptoms include cough, dyspnea, and chest pain.…”

Primary leiomyosarcoma of the heart subsequent to double carcinomas of the thyroid and lung

“…3 There have been few reports in the literature and the total number of primary cardiac leiomyosarcomas approaches only 37. [4][5][6][7][8][9][10][11] The clinical diagnosis of cardiac sarcoma is difficult because the symptoms are insidious and nonspecific. For most patients symptoms start with dyspnea, followed by cough, chest pain, palpitation, general malaise, and weight loss.…”