Primary causes of neonatal deaths in a tertiary care hospital in Delhi: an autopsy study of 331 cases

Singh, Meharban; Ak, Deorari; Vk, Paul; Mv, Murali; Mathur, Mukul

doi:10.1080/02724936.1990.11747423

Cited by 8 publications

(6 citation statements)

References 5 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Lindroth's study showed survival increase from 45 to 69% over the study period due to earlier diagnosis and treatment 25 . Pneumonia had a better outcome (80.0%) in relation to Septicemia and this finding is in conformity with the Indian study 19 . Infection of all kinds which included Septicemia and Pneumonia had poor outcome with MV.…”

Section: Methodssupporting

confidence: 90%

See 1 more Smart Citation

Immediate Outcome of Mechanically Ventilated Neonate : One Year Experience in Neonatal Intensive Care Unit of Combined Military Hospital Dhaka

et al. 2022

View full text Add to dashboard Cite

Background: A large number of neonates in intensive care unit require mechanical ventilation due to various disease conditions. There has been a dramatic fall in neonatal mortality in developed countries with the advent of mechanical ventilation. This study was carried out to see the immediate outcome of neonates who required mechanical ventilation. Materials and methods: This prospective observational study was carried out in Neonatal Intensive Care Unit, CMH Dhaka from January 2016 to December 2016. Neonates who required mechanical ventilation during the study period were enrolled in this study. During the time of mechanical ventilation neonates were followed up for any complication till discharge or death. Results: Total 30 neonates were enrolled in the study. Among them 22(73.3%) of the neonates were preterm and 8(26.7%) were term, 25(83.3%) having birth weight <2500 gm. Respiratory Distress Syndrome was the most common reason for mechanical ventilation accounting for 11(36.7%),other indications were Perinatal Asphyxia 7(23.3%), Septicemia 6(20.0%), Congenital Pneumonia 5(16.7%) and Meconium Aspiration Syndrome 1(3.3%). Common complications during the period of ventilation were Septicemia (40.0%), Acute Renal Failure (16.7%), Pneumonia (16.7%), Pulmonary Hemorrhage (10.0%), Intraventricular Hemorrhage (6.7%), Pneumothorax(10.0%) and Heart Failure (6.7%). 17(56.7%) neonates survived and 13(43.3%) were died. Most of the neonate died of Perinatal Asphyxia 4(57.1%), Septicemia 3(50.0%), RDS 5(45.5%) and Congenital Pneumonia 1(20.0%). Conclusion: The survival rate of ventilated neonates was 56.7%. The higher gestational age and birth weight was significantly associated with better outcome. Septicemia and Pneumonia (PNA) was the leading cause of death in this study. Effective measures for prevention and management of sepsis could improve the outcome of neonates in NICU. IAHS Medical Journal Vol 4(2), June 2021; 27-32

show abstract

Section: Methodssupporting

confidence: 90%

“…Nangia S et al also found commonest complication as Sepsis (26.0%) 10 . Pulmonary air leak was the common complication in western literature and in West Indies 19,17 . In the present study 3(10.0%) patient developed air leak (Pneumothorax).…”

Section: Iahs Medical Journalmentioning

confidence: 99%

Immediate Outcome of Mechanically Ventilated Neonate : One Year Experience in Neonatal Intensive Care Unit of Combined Military Hospital Dhaka

et al. 2022

View full text Add to dashboard Cite

show abstract

“…A time cycled pressure limited Respiratory distress is one of the commonest problems of newborns the world over with an incidence of 3 to 7% of all live births [1][2][3][4]. Autopsy studies reveal that 32-52% of all perinatal deaths are due to respiratory disorders [2,5]. Respiratory distress in newborns presents with tachypnea, inspiratory retractions and expiratory grunting.…”

Section: Methodsmentioning

confidence: 99%

A Two Year Experience in Continuous Positive Airway Pressure Ventilation Using Nasal Prongs and Pulse Oximetry

Malik

Gupta

2003

Medical Journal Armed Forces India

View full text Add to dashboard Cite

In a prospective study 26 of the 116 consecutive neonates suffering from respiratory distress survived on varying concentrations of humidified oxygen. Continuous positive airway pressure (CPAP) of 4-12 cm of water was applied through short nasal prongs to 90 neonates. Haemoglobin oxygen saturation (SaO2) rose in all and it was maintained steadily above 85% in 46 (51%) infants who survived. The mean duration of CPAP among the survivors was 61 hours (range 8-190 hours). Common indications of CPAP ventilation were hyaline membrane disease (HMD) (27.7%), meconium aspiration syndrome (MAS) (20%), apnea of prematurity (18.8%) and asphyxia (17.7%). Neonates weighing >1000 gm faired well with overall survival of 60 to 82.35%. However, among the 16 babies weighing <1000 gm, only 3 (18.75%) survived. 4 infants on CPAP died due to pneumothorax, none had complications of oxygen toxicity. The 44 CPAP failures, fared poorly even when shifted to intermittent positive pressure ventilation (IPPV) regardless of their weight and 1 among the 5 survivors developed grade 1 intraventricular haemorrhage. It was concluded that nasal CPAP ventilation with pulse oximetry is a simple and efficient method of treating respiratory distress in newborns. This technique can be adopted even by smaller hospitals where the equipment and expertise for IPPV and arterial blood gas (ABG) monitoring are not feasible.

show abstract

“…Excluding groups of patients, such as macerated stillbirths [25,26], or low autopsy rates through limiting the range of stillbirths or infants autopsied [17] can bias conclusions about the usefulness of the autopsy. Autopsies are more likely to be useful when no clear clinical cause of death is available or if there is a malformation, whether suspected or not; the tendency to request an autopsy or consent to one is higher in these cases [16,49].…”

Section: Autopsy Ratesmentioning

confidence: 99%

Value of the Perinatal Autopsy: Critique

Erwich²,

2002

View full text Add to dashboard Cite

In consenting to a perinatal autopsy, the primary motive of parents may be to find the exact cause of death. A critical review on the value of perinatal autopsies was performed to see whether parents could be counseled regarding their main motive. A literature search was performed in MEDLINE, EXCERPTA MEDICA, and the Cochrane library. We evaluated the value of the autopsy by comparing the clinical and autopsy diagnoses in stillbirths, neonatal deaths, and therapeutic terminations. Clinicopathologic concordance was divided into four categories: (1) change in diagnosis, (2) additional findings, (3) complete confirmation, and (4) inconclusive. We sought information on factors that may influence the value of perinatal autopsies: the type and definitions of perinatal loss; autopsy rate; level of hospital; expertise of pathologists; autopsy protocol used; whether patients were inborn or referred; and antenatal diagnosis. From the 27 articles that met our review criteria, the autopsy revealed a change in diagnosis or additional findings in 22% to 76% of cases. If confirmation of clinical findings is included, then the value of the perinatal autopsy was as high as up to 100%. Factors that could influence this rate were reported variably by investigators. When centers report their experience of the value of the perinatal autopsy, information on the factors that may influence their reports should be provided as well. Clinicians can confidently advise parents of the usefulness of the perinatal autopsy in ascertaining the cause of death or for counseling their future pregnancies.

show abstract

Primary causes of neonatal deaths in a tertiary care hospital in Delhi: an autopsy study of 331 cases

Cited by 8 publications

References 5 publications

Immediate Outcome of Mechanically Ventilated Neonate : One Year Experience in Neonatal Intensive Care Unit of Combined Military Hospital Dhaka

Immediate Outcome of Mechanically Ventilated Neonate : One Year Experience in Neonatal Intensive Care Unit of Combined Military Hospital Dhaka

A Two Year Experience in Continuous Positive Airway Pressure Ventilation Using Nasal Prongs and Pulse Oximetry

Value of the Perinatal Autopsy: Critique

Contact Info

Product

Resources

About