Primary cutaneous mucormycosis at sites of insulin injection

Successful treatment with UVA rush hardening in a case of solar urticaria

“…The eruption had started in the right chest, where it was predominant. Pemphigus vulgaris induced by radiotherapy is rare [1][2][3]6]. Three months earlier, the patient had been treated for cancer of the right breast (low-grade infiltrating ductal carcinoma), by tumorectomy and right axillary node curettage (1 of 10 lymph nodes involved), then oral hormone therapy (letrozol 2.5 mg/day).…”

“…The clinical presentation differs between these two disease processes. It typically presents as a single necrotic hemorrhagic ulcer following percutaneous inoculation of fungal spores [6]. It typically presents as a single necrotic hemorrhagic ulcer following percutaneous inoculation of fungal spores [6].…”

“…Financial support: none. Recently, the effectiveness of ultraviolet A (UVA) rush hardening therapy has been reported [5,6]. Successful treatment with UVA rush hardening in a case of solar urticaria Solar urticaria (SU) is a rare idiopathic photodermatosis.…”

“…SU is commonly treated with oral antihistamines, sunscreen, plasmapheresis and/or immunosuppressants. Recently, Masuoka et al also reported that UVA rush hardening therapy is efficacious, even in serum factor-positive SU patients, and is a safe and effective treatment [6]. However, the symptoms of SU are frequently resistant to these treatments.…”

“…Phototherapy with various wavelengths of light and methods has also been performed to induce a tolerant state [2][3][4]. One mechanism of action of UVA rush hardening therapy may be that the therapy results in the continuous blockade of binding sites for IgE on mast cells and/or the inhibition of internalization of photoantigen/IgE/FcRI complexes [6]. Recently, the effectiveness of ultraviolet A (UVA) rush hardening therapy has been reported [5,6].…”