Primary diffuse large B-cell lymphoma of the left ureter: A case report

Abstract

Abstract. Diffuse large B-cell lymphoma (DLBCL) is a subtype of non-Hodgkin lymphoma occurring in various sites, but rarely involving the ureters. Primary DLBCL is a rare entity. Imaging studies in a 82-year-old male patient revealed left hydronephrosis and an area of nodular soft tissue density in the upper ureteral wall. On enhanced computed tomography scans, the lesion exhibited early enhancement. As the lesion was considered to be malignant, a left nephroureterectomy was performed for the purpose of pathological diagnosis. Histological analysis and immunohistochemistry revealed DLBCL. Since the surgery, the patient has survived for 16 months without evidence of a relapse. Thus, in cases with ureteral stenosis or obstruction for which the cause is uncertain, the possibility of primary lymphoma of the ureter should be considered and further histopathological examination of bioptic samples should be performed as soon as possible.

Acute Kidney Injury as Presenting Symptom of Primary Lymphoma of the Uterus: Uncommon Presentation of a Rare Disease

“…However, there is no standardization regarding surgical versus nonsurgical management. There is standardization on treatment regimen, and R-CHOP chemotherapy is considered to be the most accepted and effective regimen [7]. Many of the documented reports of primary uterine and female genital tract DLBCL, including our own, show typical CD20 + markers [10].…”

“…Uterine con ned DLBCL is the rarest extranodal site of this disease, with approximately 143 reported cases in the English literature [4]. The clinical presentation of primary female genital tract lymphoma is variable and often patients complain of back pain or abnormal vaginal bleeding [6,7]. Uncommon but not a unique manifestation of this disease is severe hydronephrosis.…”

An unusual presentation of diffuse large B‐cell lymphoma with ureteric involvement: A case report

“…The treatment of ureter NHL varies and includes radiation after partial ureterectomy or chemotherapy . Majority of the patients undergo chemotherapy after diagnosis of DLBCL which is established on histopathology and receive RCHOP chemotherapy and survive for more than 6 months .…”

“…The treatment of ureter NHL varies and includes radiation after partial ureterectomy or chemotherapy. 7 Majority of the patients undergo chemotherapy after diagnosis of DLBCL which is established on histopathology and receive RCHOP chemotherapy and survive for more than 6 months. 8,9 Our patient received six cycles of RCHOP chemotherapy but he had short survival as later during the course of treatment he was diagnosed with CNS lymphoma on CT scan.…”

FDG PET/CT in a Case of Primary Lymphoma of the Ureter

“…Primary lymphoma of the ureter is extremely rare because of absence of lymphoid tissue in the ureteral wall. [4][5][6][7][8] The reported histopathologic subtypes of primary lymphoma of the ureter include diffuse large B-cell lymphoma, follicular lymphoma, small lymphocytic lymphoma, mucosa-associated lymphoid tissue lymphoma, and Hodgkin lymphoma. 6,8 The imaging findings of primary lymphoma of the ureter are rarely reported.…”