Primary Extragastrointestinal Stromal Tumor of Greater Omentum with Intraperitoneal Bleeding

Kataoka, Masatoshi; Saitoh, Takayuki R.; Kawashima, Kousaku; Yazaki, Tomotaka; Sonoyama, Hiroki; Okimoto, Eiko; Oka, Akihiko; Mishima, Yoshiyuki; Mishiro, Tsuyoshi; Oshima, Naoki; Shibagaki, Kotaro; Tobita, Hiroshi; Moriyama, Ichiro; Ishimura, Norihisa; Nagase, Mamiko; Hirahara, Noriyuki; Tajima, Yoshitsugu; Ishihara, Shunji

doi:10.2169/internalmedicine.6519-20

Cited by 8 publications

(3 citation statements)

References 23 publications

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“…Although the observation period was insufficient, the patient remained recurrence-free for up to 12 months after surgery. To the best of our knowledge, there have been only four cases of ruptured EGIST, and this is the first case that was removed by single-stage laparoscopy [12] , [13] , [14] , [15] .…”

Section: Discussionmentioning

confidence: 87%

Laparoscopic resection for spontaneously ruptured primary extragastrointestinal stromal tumor of the greater omentum: A case report

Murata

Ishimori

Naitou

et al. 2022

International Journal of Surgery Case Reports

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Section: Discussionmentioning

confidence: 87%

Laparoscopic resection for spontaneously ruptured primary extragastrointestinal stromal tumor of the greater omentum: A case report

Murata

Ishimori

Naitou

et al. 2022

International Journal of Surgery Case Reports

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“…Actually, a great number of extragastrointestinal GISTs (EGISTs) reported are metastases foci of primary GISTs. Mesentery and omentum are common tumor sites of genuine primary EGISTs ( 91 , 92 ). Other rare and unusual locations are pancreas ( 93 ), prostate ( 94 ), and pleura ( 95 ).…”

Section: Surgical Management In Gastrointestinal Stromal Tumorsmentioning

confidence: 99%

Advances of endoscopic and surgical management in gastrointestinal stromal tumors

2023

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As one of the most common mesenchymal malignancies in the digestive system, gastrointestinal stromal tumors (GISTs) occur throughout the alimentary tract with diversified oncological characteristics. With the advent of the tyrosine kinase inhibitor era, the treatment regimens of patients with GISTs have been revolutionized and GISTs have become the paradigm of multidisciplinary therapy. However, surgery resection remains recognized as the potentially curative management for the radical resection and provided with favorable oncological outcomes. The existing available surgery algorithms in clinical practice primarily incorporate open procedure, and endoscopic and laparoscopic surgery together with combined operation techniques. The performance of various surgery methods often refers to the consideration of risk evaluation of recurrence and metastases; the degree of disease progression; size, location, and growth pattern of tumor; general conditions of selected patients; and indications and safety profile of various techniques. In the present review, we summarize the fundamental principle of surgery of GISTs based on risk assessment as well as tumor size, location, and degree of progress with an emphasis on the indications, strengths, and limitations of current surgery techniques.

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“…Extragastrointestinal locations include the soft tissues of the abdomen such as the peritoneum, mesentery, and omentum [1,2]. These primary extragastrointestinal GISTs comprise fewer than 5% of cases relative to GISTs arising from the gastrointestinal (GI) tract [2][3][4].…”

Section: Introductionmentioning

confidence: 99%

An Extragastrointestinal Stromal Tumor Arising From the Omentum in a Young Hispanic Male

DeRon,

Khan

2024

Cureus

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Gastrointestinal stromal tumors (GISTs) are neoplasms arising from the bowel wall, most often in the jejunoileum of the small intestine, but rarely from extragastrointestinal locations. GISTs most often occur in patients older than 40 years of age and can present with a multitude of gastrointestinal symptoms. We present a rare case of an extragastrointestinal stromal tumor (EGIST) causing abdominal pain and melena in a 34-year-old Hispanic male. The patient presented with diffuse abdominal pain, melena, and severe anemia. Computed tomography of the abdomen revealed a large mass abutting the small bowel. The patient was taken to surgery where the mass, which appeared to be deriving from the omentum and invading the adjacent small bowel, was completely excised and found to be a spindle cell GIST. Excision margins were determined to be negative, and the patient was started on a tyrosine kinase inhibitor for maintenance therapy. The patient continues to follow up on an outpatient basis for surveillance. This case represents the rare disease entity EGIST presenting outside the typical demographics of the disease in a young patient with no identified previous genetic syndromes. Gross examination of the mass in this case was also atypical given the appearance that the mass was rooted in the omentum and invading the small bowel which would suggest the primary tumor site was extragastrointestinal. This case demonstrates the need to build a differential diagnosis that includes GIST and the ability to successfully treat this disease if it is identified early in the clinical course.

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Primary Extragastrointestinal Stromal Tumor of Greater Omentum with Intraperitoneal Bleeding

Cited by 8 publications

References 23 publications

Laparoscopic resection for spontaneously ruptured primary extragastrointestinal stromal tumor of the greater omentum: A case report

Laparoscopic resection for spontaneously ruptured primary extragastrointestinal stromal tumor of the greater omentum: A case report

Advances of endoscopic and surgical management in gastrointestinal stromal tumors

An Extragastrointestinal Stromal Tumor Arising From the Omentum in a Young Hispanic Male

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