Primary Intraocular Lymphoma (ocular reticulum cell sarcoma) Diagnosis and Management

Intraocular lymphoma: a series of 14 patients with clinicopathological features and treatment outcomes

“…[10][11][12][13][14] Our youngest patient was an immunocompetent 24-year-old woman with NK/T-cell disease whose case has already been reported. 15 The most common clinical presentation in our study was vitritis (86%).…”

Biopsy techniques and yields in diagnosing primary intraocular lymphoma

“…Primary intraocular lymphoma (PIOL) is a subset of primary central nervous system lymphoma (PCNSL) with predilection for intraocular regions that sit behind the blood-retina barrier [1][2][3][4]. PIOL is a unique malignant lymphoproliferation because of its affectation of an immune privileged site, involving the subretinal pigment epithelium (RPE), retina, vitreous, and optic nerve.…”

“…It is important to realize that, if a patient is suspected of having PIOL, a lumbar puncture with cytologic analysis of the cerebrospinal fluid (CSF) should be performed because of the high possibility of brain involvement in PIOL [1,3,[7][8][9]. In addition, patients should also receive a brain magnetic resonance imaging (MRI) scan to determine whether lesions are present in the absence of obvious lymphoma cells in the CSF.…”

Cytopathologic Diagnosis of Benign Lesions Simulating Choroidal Melanomas

“…[1][2][3][4][5] There is a paucity of data on its diagnostic accuracy for nonmalignant intraocular masses, although a few cases of false-positive results have been reported. 6 Diagnosis of anterior intraocular tumors is often difficult.7 The ultrasonographic pattern of lesions in this location is not as diagnostic as in the posterior pole, and fluorescein angiography has limited utility for anterior choroid and ciliary body tumors.8,9 We report three cases of benign pigmented proliferations that had a sufficiently characteristic fine-needle aspiration biopsy pattern to differentiate them from uveal melanoma in the operating room prior to resection of the lesions.…”