Primary intraosseous squamous cell carcinoma in a dentigerous cyst

Panneerselvam, Karthika; Parameswaran, Anantanarayanan; Kavitha, B; Panneerselvam, Elavenil

doi:10.4103/2278-330x.214579

Cited by 13 publications

(7 citation statements)

References 4 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…123 Moreover, malignant neoplasms may arise de novo, whereas others can evolve through the malignant transformation of benign lesions. [123][124][125][126][127][128][129][130][131][132][133][134][135][136][137][138] While most odontogenic lesions affect individuals during early and middle adulthood (between the third and fifth decades of life), malignant tumors associated with dental follicles affect individuals between the fifth and eighth decades. 64,123 Dental follicles may harbor genetic changes as early signs of pathological transformation.…”

Section: Morphological/ Molecular Histology (Hande) Ihc (Ck14 Ck18)mentioning

confidence: 99%

Revisiting the human dental follicle: From tooth development to its association with unerupted or impacted teeth and pathological changes

Bastos

Gomez

Gomes

2021

Developmental Dynamics

View full text Add to dashboard Cite

Dental follicles are involved in odontogenesis, periodontogenesis, and tooth eruption. Dental follicles are unique structures, considering that their remnants can persist within the jawbones after odontogenesis throughout life if the tooth does not erupt. Pathological changes may occur in these tissues as individuals age. The changes range from benign to life threatening. Thus, the assessment of age-related changes in dental follicles associated with unerupted teeth is of paramount importance. In this review, we summarize the physiological roles and changes in dental follicles in odontogenesis, tooth eruption, and aging, in addition to the pathological changes associated with these structures. We encourage investigators to consider this peculiar tissue as a unique model and explore its potential to clarify its importance from the viewpoints of developmental biology, tissue physiology, and pathology.

show abstract

Section: Morphological/ Molecular Histology (Hande) Ihc (Ck14 Ck18)mentioning

confidence: 99%

Revisiting the human dental follicle: From tooth development to its association with unerupted or impacted teeth and pathological changes

Bastos

Gomez

Gomes

2021

Developmental Dynamics

View full text Add to dashboard Cite

show abstract

“…After cross-checking the last 3 reviews on the subject, only 35 cases have been reported from 1958 to 2015 [ [2] , [3] , [4] ]. In addition two other cases were published in 2017 and 2020 in English literature [ 5 , 6 ].…”

Section: Discussionmentioning

confidence: 99%

Primary intraosseous carcinoma arising in dentigerous cyst: Case report

Marchal

Gérard

Curien

et al. 2020

International Journal of Surgery Case Reports

View full text Add to dashboard Cite

Highlights Primary intraosseous carcinoma arising in a dentigerous cyst is a rare observation. There are no clinical or radiological pathognomonic characteristics and the diagnosis is often made fortuitously. A surgical excision with clear margin is the cornerstone of treatment. A systematic and careful microscopic analysis of any cyst, even if look like benign, should be undertaken.

show abstract

“…In this line, epithelial rests of Malassez, dental lamina and epithelium of the dental follicle represent potential suspects 6 . It was also observed that long‐standing chronic inflammation in the benign odontogenic cyst was the most probable etiopathological factor responsible for the malignant transformation of a benign cystic lining 7–9 …”

Section: Introductionmentioning

confidence: 99%

“…6 It was also observed that longstanding chronic inflammation in the benign odontogenic cyst was the most probable etiopathological factor responsible for the malignant transformation of a benign cystic lining. [7][8][9] PIOC arising in a dentigerous cyst is a rare observation. PIOC from odontogenic cysts have an incident rate of 0.3%-2% and only 16%-51% of them are PIOC from dentigerous cyst.…”

Section: Introductionmentioning

confidence: 99%

A primary intraosseous squamous cell carcinoma case report and literature review. The new WHO classification

et al. 2022

View full text Add to dashboard Cite

Aim: Cyst-like lesions in the mandible rarely develop into malignancies, and the reported incidence is between 0.3% and 2%. The present study describes a rare case of primary intraosseous squamous cell carcinoma of the mandible arising from an odontogenic cyst. Materials and Methods:An 80-year-old male was referred to Trieste University Maggiore Hospital (Trieste, Italy), with acute pain in the left retromolar area.An initial examination revealed extra oral swelling without paresthesia of the IAN.Following an intraoral examination, the oral mucosa was edematous, percussion pain was experienced on the lower left second molar. Panoramic radiography revealed a retained lower left wisdom tooth and an irregular radiolucent area between the lower left second molar and the mandibular angle with clear margins. Computed tomography revealed diffuse bone resorption and an extensive loss of cortical bone on the lingual side. Results:A biopsy was performed during the surgery to remove the second lower left molar and the wisdom tooth, the pathological diagnosis was of squamous cell carcinoma arising from the epithelial lining of the odontogenic cyst. MRI with contrast agent was also performed. Shortly after the patient has been proposed a complete resective surgery of the mass including the infiltrated areas and then a reconstructive part to restore the function and aesthetic. Conclusion:The follow-up of a large inflammatory cyst is essential for early diagnosis of malignant neoplasm. This approach allows lower invasive treatments and major survival of these patients.

show abstract

Primary intraosseous squamous cell carcinoma in a dentigerous cyst

Cited by 13 publications

References 4 publications

Revisiting the human dental follicle: From tooth development to its association with unerupted or impacted teeth and pathological changes

Revisiting the human dental follicle: From tooth development to its association with unerupted or impacted teeth and pathological changes

Primary intraosseous carcinoma arising in dentigerous cyst: Case report

A primary intraosseous squamous cell carcinoma case report and literature review. The new WHO classification

Contact Info

Product

Resources

About