Primary Intrasellar Coccidioidomycosis Simulating a Pituitary Adenoma

Scanarini, M.; Rotilio, Antonino; Rigobello, Luca; Pomes, A.; Parenti, Anna; Alessio, L

doi:10.1227/00006123-199105000-00022

Cited by 23 publications

(12 citation statements)

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“…2,3 . Cases of mycotic abscesses have been reported due to Aspergillus 20,21 , Candida 22 , coccidiodomycosis 23 , histoplasmosis 24 and blastomycosis 25 . In contrast to bacterial pituitary abscesses, most fungal infections are associated with some type of immunosuppressed patients 18 .…”

Section: Discussionmentioning

confidence: 99%

Primary pituitary abscess: case report

Hanel

Koerbel

Prevedello

et al. 2002

Arq. Neuro-Psiquiatr.

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-Pituitary abscesses are potentially life-threatening lesions if not appropriately diagnosed and treated. The authors have operated on more than five hundred cases of pituitary tumors and only one represented a case of pituitary abscess. A 35-year-old woman was investigated for chronic frontal headache. CT scan showed a cystic sellar lesion with ring enhancement after contrast injection leading to an initial diagnosis of pituitary adenoma. She underwent a sublabial transsphenoidal approach to the pituitary gland. After dural opening, purulent material was obtained and no tumor or other associated lesion was detected. There was no evidence of current or previous septicemic illness, meningitis, cavernous sinus thrombosis or sinus infection. Cultures were negative. She was put on antibiotics and discharged after 4 weeks. Nowadays, 10 years after treatment, she is doing well, with no anterior pituitary hormone deficit. MRI shows a partially empty sella without residual lesion and the pituitary stalck is in the midline. The early diagnosis and adequate treatment of this life-threatening lesion may result in excellent prognosis.KEY WORDS: abscess, pituitary gland, hypophysis. Abscesso primário de hipófise: relato de casoRESUMO -Abscessos pituitários são lesões potencialmente graves se não diagnosticadas e tratadas de maneira apropriada. Os autores têm mais de 500 casos de tumores pituitários operados e apenas um único caso de abscesso pituitário. Uma mulher de 35 anos foi investigada por cefaléia frontal crônica. A tomografia computadorizada de crânio mostrou uma lesão selar cística com captação de contraste levando à hipótese diagnóstica inicial de adenoma hipofisário. A paciente foi submetida a um acesso sublabial transesfenoidal para a hipófise. Após abertura dural, foi encontrado material purulento sem sinal de tumor ou outra lesão associada. Não havia evidência de doença séptica prévia ou atual, meningite, trombose de seio cavernoso ou sinusite. Culturas foram negativas. A paciente foi submetida a tratamento com antibióticos e recebeu alta após 4 semanas. Atualmente, após 10 anos do tratamento, encontra-se sem déficit hormonal hipofisário anterior. Sua ressonância magnética de crânio mostra uma sela parcialmente vazia sem lesão residual, com o talo hipofisário na linha média. O diagnóstico e tratamento adequado desta lesão potencialmente grave pode resultar em excelente prognóstico. PALAVRAS-CHAVE: abscesso, glândula pituitária, hipófise.

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Section: Discussionmentioning

confidence: 99%

Primary pituitary abscess: case report

Hanel

Koerbel

Prevedello

et al. 2002

Arq. Neuro-Psiquiatr.

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“…Fungal infections (aspergillosis and coccidiomycosis) [54], cysticercosis [55], and neurosyphilis [56] are rare.…”

Section: Other Infectionsmentioning

confidence: 99%

Rare Sellar Lesions

Glezer

Paraíba

Bronstein

2008

Endocrinology and Metabolism Clinics of North America

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“…Serology, culture, and cytology may reveal the etiology, but biopsy of the mass provides the best method for diagnosis when serology and culture are negative for C. immitis. 7 In many cases, the risks of a biopsy of an intracranial mass are determined to be too significant to the patient, so pathology of the intracranial mass is not known until an autopsy is performed. Schlumberger 4 described a fatal case of coccidioidal brain lesions in a patient in whom spherules of C. immitis were also found in the sputum.…”

Section: Introductionmentioning

confidence: 99%

“…A case involving a male with diabetes mellitus reported by Rhoden 9 also had a left cerebellar coccidioidal lesion. According to Scanarini, 7 the characteristic lesion of coccidioidomycosis is that of a diffuse granulomatous lesion that encases the brain and may obstruct the flow of CSF. The basiliar region is often involved, especially in cases involving meningitis.…”

Section: Introductionmentioning

confidence: 99%

Deep Solitary Brain Mass in a Four‐Month‐Old Male with Disseminated Coccidioidomycosis

Nolt¹,

Geertsma²

2007

Annals of the New York Academy of Sciences

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Parenchymal brain involvement from disseminated coccidioidomycosis occurs rarely and there are few documented pediatric cases. We report a four-month-old male infant with a cerebellar lesion seen in the brain on computed tomography (CT). Coccidioides immitis (C. immitis) grew on bronchoscopic fluid samples and serum titers to C. immitis were 1:1024. Antifungal treatment was initiated and after 3 months, CT scans demonstrated brain mass resolution and serum titers were decreased.

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Primary Intrasellar Coccidioidomycosis Simulating a Pituitary Adenoma

Cited by 23 publications

References 0 publications

Primary pituitary abscess: case report

Primary pituitary abscess: case report

Rare Sellar Lesions

Deep Solitary Brain Mass in a Four‐Month‐Old Male with Disseminated Coccidioidomycosis

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