Primary Liposarcoma of the Cervix: A Case Report

Abstract

A case of primary liposarcoma of the cervix is described in a 59‐year‐old postmenopausal female who was diagnosed clinically as having a cervical fibroid. Pathologic features and the probable histogenesis are discussed. Primary liposarcoma of the cervix does not appear to have been described in the literature.

Pleomorphic Liposarcoma of the Uterus: Case Report and Literature Review

“…Some of the tumors may have arisen from a leiomyoma (1) differentiation (2,21). We believe that the benign smooth muscle present at the periphery of the tumor in the present case likely represents remnants of the uterosacral ligament rather than an leiomyomatous component of the tumor.…”

“…The features of the six previously described uterine liposarcomas are summarized in Table 1. Most of these reports contained photomicrographs depicting convincing liposarcomatous differentiation of various types (see Table 1), except for one report without illustrations (3) and another that did not show convincing lipoblasts (1). The degree of sampling was not indicated in these reports, and thus a malignant mullerian mixed tumor (MMMT) with liposarcomatous differentiation might have been overlooked in some of these cases.…”

“…Liposarcoma of the uterus is a rare neoplasm; only four case reports (1)(2)(3)(4) in the English language literature and two in the German literature (5,6) exist. We report herein a case of liposarcoma of the lower uterine segment that had two unusual features: an association with tamoxifen treatment and the histology of a pleomorphic liposarcoma, an uncommon neoplasm that has been only recently described (7)(8)(9)(10)(11)(12).…”

Liposarcoma Arising in Uterine Lipoleiomyoma

“…Liposarcoma rarely involves the female genital tract and in this region it most frequently develops within the uterus with 10 cases having been reported. 4,14,18,20,25,31,32,39,41,43 Of these, 2 arose in association with a leiomyoma.…”

Aggressive Clinical Behavior of a Rare Uterine Sarcoma

“…In 1923, Peterson noted 2 cases of liposarcoma in an analysis of 31 cases of uterine lipomas [4]. A pure liposarcoma of the cervix in a leiomyomatous uterus was described by Veliath and colleagues in 1978 [5]. Gleeson and colleagues reported a 45-year-old patient with endometrial adenocarcinoma who also had a welldifferentiated sclerosing liposarcoma involving the right ovary [6].…”