Primary malignant neoplasms of orofacial origin: a retrospective review of 256 cases in a Nigerian tertiary hospital

Ajayi, Owolabi; Adeyemo, WL; Ladeinde, Akinola Ladipo; Ogunlewe, M.O.; Effiom, Olajumoke Ajibola; Omitola, Olufemi Gbenga; Arotiba, Godwin Toyin

doi:10.1016/j.ijom.2007.01.007

Cited by 45 publications

(77 citation statements)

References 37 publications

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“…Uma média de idade maior em comparação com as outras lesões deste estudo pode ser associada a uma exposição crônica e excessiva a carcinógenos por um extenso período de tempo 24 . O carcinoma de células escamosas teve o lábio inferior como sítio mais comum, o que difere da literatura 21,22,25 , que cita a língua, o assoalho bucal e a gengiva mandibular como as principais localizações, às quais se atribui um acúmulo de carcinógenos presentes no tabaco, no álcool e nos alimentos, que são dissolvidos na saliva nessas áreas da cavidade oral. Um estudo brasileiro, no entanto, encontrou o lábio inferior como sítio mais comum do câncer oral 26 .…”

Section: As Lesões Odontogênicas Inflamatórias Mais Prevalentes Foramunclassified

Lesões maxilofaciais: um levantamento de 762 casos da Universidade Federal de Sergipe, Brasil

Souto

Piva

Martins-Filho

et al. 2014

Rev. odontol. UNESP

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ResumoIntrodução: A pesquisa epidemiológica de lesões maxilofaciais em determinada região estabelece as necessidades populacionais e orienta os profissionais da saúde na definição de ações preventivas e tratamento adequado. Objetivo: Analisar os laudos histopatológicos de lesões maxilofaciais do período de 1996 a 2011 do Laboratório de Patologia Oral do Departamento de Odontologia da Universidade Federal de Sergipe (UFS), Brasil. Material e método: Estudo retrospectivo das biópsias realizadas de 1996 a 2011, recuperando-se os dados referentes ao gênero e à idade dos pacientes, à localização das lesões e ao diagnóstico histopatológico. As lesões foram agrupadas em: neoplasias benignas, lesões potencialmente malignas, neoplasias malignas, lesões inflamatórias, lesões odontogênicas, lesões ósseas, lesões de glândulas salivares e anomalias de desenvolvimento. Resultado: Foram analisados 762 laudos, havendo maior prevalência das lesões inflamatórias (n=205, 26,9%). O diagnóstico mais comum entre as neoplasias benignas foi a lesão periférica de células gigantes (n=15); entre as lesões potencialmente malignas, foi a displasia epitelial (n=80), e entre as neoplasias malignas, foi o carcinoma de células escamosas (n=29). Dentre as lesões inflamatórias, a lesão mais prevalente foi a hiperplasia fibrosa inflamatória (n=74). O granuloma periapical (n=62) foi a lesão mais comum dentre as lesões odontogênicas. A lesão mais prevalente dentre as lesões ósseas foi o fibroma ossificante central (n=08); entre as lesões de glândulas salivares, foi o fenômeno de retenção de muco (n=64), e entre as anomalias de desenvolvimento, foi a mácula melanocítica (n=04). Conclusão: Os achados deste levantamento salientam a importância de planos de tratamento e medidas educativas que diminuam e previnam a exposição dos pacientes a fatores de risco.Descritores: Prevalência; patologia bucal; histologia. AbstractIntroduction: Epidemiological survey of maxillofacial lesions in a specific geographic region establishes the real needs of this population and guides health professionals in defining preventive actions and appropriate treatment. Objective: To analyze the histopathological diagnosis of maxillofacial lesions issued in the period 1996-2011 managed by the Laboratory of Oral Pathology, Department of Dentistry, Federal University of Sergipe, Brazil. Material and method: A retrospective study of biopsies removed from 1996-2011 was conducted, recovering data related to gender and age of the patients, location of the lesions and histopathological diagnosis. The lesions were grouped into eight diagnostic categories: benign neoplasms, potentially malignant lesions, malignant neoplasms, inflammatory lesions, odontogenic lesions, bone lesions, salivary gland lesions and malformations and developmental anomalies. Result: 762 reports were analyzed, with a higher prevalence of inflammatory lesions (n = 205, 26.9 %). The most common diagnosis among benign neoplasms was the peripheral giant cell granuloma (n=15), among potentially malignant lesions was the...

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Section: As Lesões Odontogênicas Inflamatórias Mais Prevalentes Foramunclassified

Lesões maxilofaciais: um levantamento de 762 casos da Universidade Federal de Sergipe, Brasil

Souto

Piva

Martins-Filho

et al. 2014

Rev. odontol. UNESP

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“…In Lagos, South-West Nigeria, a study by Arotiba et al [20] on all patients who presented with cancer arising in the oral cavity and adjacent structures at the Lagos University Teaching Hospital (a tertiary referral centre) over a 15-year period (1978)(1979)(1980)(1981)(1982)(1983)(1984)(1985)(1986)(1987)(1988)(1989)(1990)(1991)(1992) reported a prevalence rate of 9.67% of all cancer. Also in that same center, a prevalence rate of 18% of oral cancers from all orofacial biopsies from 1993 to 2003 was reported by Ajayi et al [19]. Amusa et al [23] in Ile Ife, South-West Nigeria reported that oral cancers accounted for 36.8% of head and neck malignancies (Table 1).…”

Section: Epidemiology Of Oral Cancer In Nigeriamentioning

confidence: 65%

“…Several prevalence rates of oral cancers have been reported by several authors in different geopolitical locations in Nigeria. Orofacial carcinomas were reported mostly in the older age groups while the Orofacial sarcomas were mostly found in the slightly younger age groups [15,[18][19][20]. North central Nigeria reported that oral cancers constitute 7.6% of head and neck cancers (HNC) from a 15-year study of which carcinomas, sarcomas and lymphomas were 81.5%, 16.7% and 1.8% of the cases respectively [21].…”

Section: Epidemiology Of Oral Cancer In Nigeriamentioning

confidence: 99%

“…A study in Calabar [15] Nigeria reported a peak incidence of squamous cell carcinoma in the sixth and seventh decades while Burkitt's lymphoma and rhabdomyosarcoma were observed around the first decade. Orofacial carcinomas were reported mostly in the older age groups while the Orofacial sarcomas and lymphomas were mostly found in the slightly younger age groups [15,19]. Ajayi et al in Lagos [19] reported 75% of oral carcinomas occurring above 40 years of age.…”

Section: Age Distribution Of Oral Cancermentioning

confidence: 99%

“…Orofacial carcinomas were reported mostly in the older age groups while the Orofacial sarcomas and lymphomas were mostly found in the slightly younger age groups [15,19]. Ajayi et al in Lagos [19] reported 75% of oral carcinomas occurring above 40 years of age. Patients with carcinoma were older than those with sarcomas and lymphomas (P<0.01), while those with lymphomas were significantly younger than those with sarcomas (P<0.01) [19].…”

Section: Age Distribution Of Oral Cancermentioning

confidence: 99%

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Oral Cancer- The Nigerian Perspective

Okoh¹,

Okoh²

2017

J Mol Biomark Diagn

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Study background: In our environment, oral cancer is one of the most common lethal diseases encountered in dental practice. It is frequently diagnosed in the late stages because most patients present late in the course of the disease. This may be attributed to their low socioeconomic status, illiteracy, and some traditional beliefs in alternative native therapies. Some authors have reported on oral cancers specifically in their individual geographic settings; however, there is a paucity of reviews on Oral cancers generally in our environment. This study aims to review the prevalence, awareness and clinicopathologic patterns of oral cancers across the different geographic zones in Nigeria.Methods: Information was sourced from journals, electronic data base such as Medline, Pubmed, Elsevier ScienceDirect and personal research work.Result: Several prevalence rates have been reported in different geopolitical locations in our environment. Orofacial carcinomas were reported mostly in the older age groups while the Orofacial sarcomas were found in the slightly younger age groups. Squamous cell carcinoma was the predominant histopathological type. There is a low level of awareness of these lesions among the low socio-economic groups which makes them present late in our health care facilities hence a poor prognosis. Conclusion:There is a need for increased awareness, advocacy and preventive care and early detection.

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Oral lesion as the primary diagnosis of non-Hodgkin’s lymphoma: a 20-year experience from an oral pathology service and review of the literature

Kusuke

Custódio

Sousa

2019

Eur Arch Otorhinolaryngol

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Primary malignant neoplasms of orofacial origin: a retrospective review of 256 cases in a Nigerian tertiary hospital

Cited by 45 publications

References 37 publications

Lesões maxilofaciais: um levantamento de 762 casos da Universidade Federal de Sergipe, Brasil

Lesões maxilofaciais: um levantamento de 762 casos da Universidade Federal de Sergipe, Brasil

Oral Cancer- The Nigerian Perspective

Oral lesion as the primary diagnosis of non-Hodgkin’s lymphoma: a 20-year experience from an oral pathology service and review of the literature

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