Primary Malignant Rhabdoid Tumor of the Stomach, a Rare Case Report and Review of Literature

Abstract

Rhabdoid tumor is a distinct entity reported in renal and extrarenal sites. There have been very rare reported cases in the stomach, all of which have shown an aggressive clinical course. Herein, we report a primary gastric neoplasm in an old man who presented with profuse intractable GI bleeding and undergone emergency surgery. Resected specimen showed primary malignant rhabdoid tumor. The patient died 24 h after surgery with no additional therapy. Our case emphasizes on this very rare subtype of gastric tumor, with extremely aggressive behavior.

Switch/Sucrose Non-Fermentable Complex-Deficient Rhabdoid Carcinoma of Stomach: A Rare Case Report and Literature Review

“…Twelve patients with vimentin-positive gastric cancer with rhabdoid appearance by Utsunomiya et al were excluded because of the incomplete data. 13 The remaining 30 patients were described in 16 studies 1–3,7,14–25 (Table 2) and included 23 men and 7 women, aged 30 to 86 years old (average age: 64 years). Those older than 60 years accounted for two thirds of the study subjects.…”

“…1,2 It usually consists of pure rhabdoid cells, or in some tumors, is mixed with better-differentiated components, such as adenocarcinoma, and has a poor prognosis. [3][4][5] Rhabdoid tumors were first described by Beckwith and Palmer related to children's Wilms tumors. 6 Similar tumors have been reported successively in extrarenal organs such as the central nervous system, lung, ovary, gastrointestinal tract, and pancreas.…”

Imaging Findings of a Malignant Rhabdoid Tumor in the Stomach: A Case Report

“…신장 외에서 발생한 경우 신외성 MRT라고 하며 중추신경계, 간, 뇌, 피부, 연조직 등에서 드물게 보고되었다( 2 ). 위에서 발생한 MRT는 매우 드물고( 3 4 5 6 7 ), 진단 당시에 이미 진행된 병기인 경우가 많아 예후가 좋지 않다.…”

“…지금까지 위에서 발생한 MRT는 매우 드물게 보고되었고( 3 4 5 6 7 ), 대부분 조직병리학적 소견에 중점을 두고 있어 영상 소견에 대해 알려진 바가 많지 않다. Abdullah 등( 9 )은 신외성 MRT가 영상에서 조영증강되는 부분과 조영증강이 되지 않는 괴사를 동반하는 이질성 종양으로 보인다고 하였다.…”

All Children with Malignant Rhabdoid Tumors Should Be Treated Initially with Intensive Chemotherapy

“…Brennan et al reported in 2013 a review of extracranial rhabdoid tumors, showing that only 55 children younger than 15 years were diagnosed with MRT in the UK between 1993 and 2010 [2]. MRT can be detected in almost any part of the body [3] such as liver, stomach [4], retroperitoneum, heel [5], bladder, oesophagus [6] . .…”