Primary Mucocutaneous Tuberculosis of Nose: One Decade Study

Background An attempt was made to study ENT manifestations in tuberculosis. Material and methods A descriptive study was carried out among 200 patients with ENT manifestations of tuberculosis attending various departments at a government medical college hospital. Patients will be evaluated and followed up according to protocol. All patients diagnosed with tuberculosis were treated, according to the recent RNTCP guidelines using the CBNAAT testing. Results In the present study, 66% of patients with tuberculosis of the ear, nose, and throat region were females. Seventy-five percent of patients with tuberculosis of ENT and neck region were between the age group of 11 and 40 years. Cases of tubercular lymphadenitis (89.5%), tubercular laryngitis (4.5%), tubercular otitis media (3%), TB of the oral cavity (2%), and TB of the nose (1%) were seen. Painless lymph node enlargement was found in 91.62% of cases. Lymph node enlargement, hoarseness of voice, painless profuse otorrhoea, hearing loss, nasal obstruction, rhinorrhea, odynophagia, ulcers in the oral cavity, and tonsil enlargement were seen in patients of respective ENT tuberculosis. Concomitant pulmonary TB was found in 8.37% of cases of cervical TB, 100% of cases of laryngeal TB, 50% of cases of TB otitis media, 75% of cases of oral TB, and 50% of cases of nasal TB. Biopsy and CBNAAT have a promising role in tuberculosis management. Conclusion Early diagnosis of tuberculosis in ENT requires a high index of suspicion for patients non-responding to routine treatment

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“…Similar to Gupta et al study, the biopsy was positive in all (100%) cases of nasal tuberculosis [38].…”

Section: Tuberculosis Of the Nasal Cavitysupporting

confidence: 81%

ENT manifestation CCs in tuberculosis: a descriptive study

Chavan

Ingole

Parokaran

et al. 2022

Egypt J Otolaryngol

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“…Although head and neck TB is fairly common in extrapulmonary manifestations, primary nasal TB without pulmonary involvement has always been extremely rare even in countries with high Tb burden such as India [4,6]. Nasal TB is found predominantly among females and in the elderly, especially in people with poor socioeconomic backgrounds [7], which correlates to our patient in the presenting case.…”

Section: Figure 13: Resolved Middle Turbinate Lesionsupporting

confidence: 73%

“…Nasal TB is found predominantly among females and in the elderly, especially in people with poor socioeconomic backgrounds [7], which correlates to our patient in the presenting case. The most common routes of infection for nasal TB are usually secondary to pulmonary TB via direct spread, hematogenous, lymphatic route, or in the form of lupus vulgaris in cutaneous lesion [6].…”

Section: Figure 13: Resolved Middle Turbinate Lesionmentioning

confidence: 99%

Primary Nasal Tuberculosis Masquerading as Granulomatosis With Polyangiitis: A Case Report of Diagnostic Dilemma

Shu Jiun,

Kamel,

Arasu

et al. 2023

Cureus

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Primary nasal tuberculosis (TB) is a rare disease even in areas with high TB burden, possibly attributed to the protective mechanism of sinonasal mucosa. Its symptoms are subtle and can be mistaken for other granulomatous inflammatory conditions. We would like to report a case of a 70-year-old Indian lady who underwent a successful left endoscopic dacryocystorhinostomy three years ago and presented with recurrent left epiphora. During nasal endoscopy, multiple ulcerative masses with crusting were detected over the left nasal vestibule, anterior nasal septum, left inferior, and middle turbinate. Biopsy of the nasal mass revealed granulomatous inflammation without caseating necrosis. Initially, all TB-related tests were negative. As the patient had granulomatous nasal lesions with microscopic haematuria, granulomatosis with polyangiitis (GPA) was suspected. Regrettably, the patient did not respond to treatment. A repeated tissue culture at a later stage finally detected mycobacterium tuberculosis without the presence of pulmonary tuberculosis. Considering the current TB prevalence in the Southeast Asian region, it is crucial for otorhinolaryngologists to be aware of primary nasal TB when encountering unusual head and neck lesions, even in the absence of pulmonary TB.

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Benign and malignant cutaneous nasal lesions

Sarikhani,

Zhao,

Polacco

et al. 2024

Eye & ENT Research

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The nose is a structure of both cosmetic and functional importance. Cutaneous lesions of the nose occasionally represent a diagnostic challenge and involve the expertise of several specialties from dermatology, otolaryngology—head and neck surgery, infectious disease, and pathology, among others. We present a review of salient features of malignant and benign cutaneous nasal lesions which are of importance to physicians treating these complicated pathologies.

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Primary Mucocutaneous Tuberculosis of Nose: One Decade Study

Cited by 3 publications

References 5 publications

ENT manifestation CCs in tuberculosis: a descriptive study

ENT manifestation CCs in tuberculosis: a descriptive study

Primary Nasal Tuberculosis Masquerading as Granulomatosis With Polyangiitis: A Case Report of Diagnostic Dilemma

Benign and malignant cutaneous nasal lesions

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