Primary orbital neuroblastoma in a neonate

Mirzai, Hasan; Başer, Esin; Tansuğ, Nermin; Neşe, Nalan; İşisağ, Aydın

doi:10.4103/0301-4738.27078

Cited by 12 publications

(15 citation statements)

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“…All five patients were already >1 year old at diagnosis and were in stage IV with metastasis to the bone. In contrast, the patient described by Mirzai et al . and the present patient both differed to that; that is they were both <1 month old at onset, had the same INSS staging (I), and had no infiltration to periorbital bone or bone marrow.…”

Section: Discussioncontrasting

confidence: 82%

“…In contrast, primary orbital neuroblastoma, which is very rare, is thought to arise from the ciliary ganglion, not from periorbital bone . To the best of our knowledge, only one case other than the present one has been reported as a primary orbital neuroblastoma in a child, that patient being a 2‐day‐old girl reported by Mirzai et al .…”

Section: Discussionmentioning

confidence: 51%

“…To the best of our knowledge, only one case other than the present one has been reported as a primary orbital neuroblastoma in a child, that patient being a 2‐day‐old girl reported by Mirzai et al . who had no lesions other than an orbital mass, and the tumor was thought to arise from the ciliary ganglion, not from periorbital bone …”

Section: Discussionmentioning

confidence: 99%

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Primary orbital neuroblastoma in a 1‐month‐old boy

Inazawa

Hatakeyama

Hori

et al. 2014

Pediatrics International

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Neuroblastoma is a malignant tumor predominantly occurring in children and usually arising from the adrenal gland or sympathetic ganglia. We describe a neuroblastoma in a 1-month-old boy arising from his left orbital cavity. This tumor was refractory to chemotherapy or radiotherapy, requiring enucleation of the left eye for complete removal of the intraorbital tumor. Thereafter, he received high-dose chemotherapy followed by autologous peripheral blood stem cell transplantation, and has been in complete remission for 3 years. Unlike neuroblastomas arising from the adrenal gland or sympathetic ganglia, primary orbital neuroblastoma may be refractory even in early infancy.

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Section: Discussioncontrasting

confidence: 82%

Section: Discussionmentioning

confidence: 51%

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Primary orbital neuroblastoma in a 1‐month‐old boy

Inazawa

Hatakeyama

Hori

et al. 2014

Pediatrics International

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“…Neuroblastoma is a malignant tumor of the primitive neuroblasts. [ 1 2 ] It is the second most common orbital tumor in children, after rhabdomyosarcoma accounting for 10–15% of childhood tumors. [ 1 3 4 ] Primary orbital neuroblastoma has been rarely reported in adults.…”

mentioning

confidence: 99%

“…[ 1 2 ] It is the second most common orbital tumor in children, after rhabdomyosarcoma accounting for 10–15% of childhood tumors. [ 1 3 4 ] Primary orbital neuroblastoma has been rarely reported in adults. [ 5 6 ] Frequent sites of primary neuroblastoma are abdominal, thoracic, cervical, and pelvic locations.…”

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confidence: 99%

Primary orbital neuroblastoma with intraocular extension

Vallinayagam

Rao

Pandian

et al. 2015

Indian J Ophthalmol

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Neuroblastoma is an undifferentiated malignancy of primitive neuroblasts. Neuroblastoma is among the most common solid tumors of childhood. Orbital neuroblastoma is typically a metastatic tumor. In this case report, we describe a 2-year-old child with a rapidly progressing orbital tumor. Computed tomography revealed an orbital mass lesion with extraocular and intraocular components. An incisional biopsy was done, and a histopathological examination showed features suggestive of neuroblastoma. Systemic workup including ultrasonography of the abdomen, chest roentgenogram, whole body computed tomography, and bone scintigraphy showed no evidence of systemic involvement. The diagnosis of primary orbital neuroblastoma was made, and the child was subjected to chemotherapy followed by rapid melting of the tumor. Neuroblastoma should be considered in the differential diagnosis of childhood orbital tumors.

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Pediatric Orbital Tumors

Dutton¹,

Escaravage²

2010

Ophthalmic Oncology

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Primary orbital neuroblastoma in a neonate

Cited by 12 publications

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Primary orbital neuroblastoma in a 1‐month‐old boy

Primary orbital neuroblastoma in a 1‐month‐old boy

Primary orbital neuroblastoma with intraocular extension

Pediatric Orbital Tumors

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