Primary orbital tumors: A review of 122 cases during a 23-year period: A histo-clinical study in material from the ENT Department of the Medical University of Silesia

Abstract

BackgroundThe aim of this study was to investigate the distribution of different types of primary orbital tumors, histopathological diagnosis, and postoperative complications.Material/MethodsWe analyzed 122 patients (68 women and 54 men) with orbital tumors, hospitalized in the ENT Department of the Medical University of Silesia in Katowice during 1990–2013. The patients were characterized in terms of anatomic, topographical, histopathological, and clinical parameters. The role of diagnostic imagining such as CT, NMR, and fine-needle aspiration (FNB) in preoperative diagnostics is discussed. Results of FNB, cytological, and histopathological examination of the postoperative specimens were compared.ResultsThere were 56 (46%) patients with malignant tumors, 42 (34%) with benign tumors, 19 (16%) with inflammatory tumors, and 5 patients (4%) had other tumors. In cases of malignant tumors, local recurrence up to 5 years was found in 36 (64.3%) cases. In the other 20 (35.7%) cases of malignant tumors, the patients remained under close follow-up in the outpatient clinic, without signs of local recurrence (follow-up 1–17 years). According to histopathological examination, malignant tumors were detected in 45.9% of patients and non-malignant tumor in 34.4% of patients. In 19.7% of patients, inflammatory and other types of tumors were diagnosed.ConclusionsWe characterized the occurrence and pathological profiles of orbital tumors. The tumor location, histopathological diagnosis, and postoperative complications give us important information for the diagnosis of tumor prior to biopsy or tumor resection and for the determination of the treatment strategy and possible complications after surgery.

Surgical treatment of orbital tumors in a single center: Analysis and results

“…Markowski et al . [ 30 ] divided the site of the tumors into four areas: upper lateral, upper medial, lower lateral, and lower medial on the basis of image studies. Boari et al .…”

Adult Orbital Lesions in Saudi Arabia: A Multi-centered Demographic Study with Clinicopathological Correlation

“…Similar findings were reported by Demirci et al [ 7 ] who found that the most common clinical features at presentation were a periorbital palpable mass (26%), followed by proptosis (18%) and pain (15%). Markowski et al [ 22 ] found that the most frequent manifestations were proptosis in 100% of patients, eyelid swelling in 54%, limitation of eye movement in 45%, decreased visual acuity in 43%, pain in 30%, and diplopia in 16%. In our series, we observed that most of the lymphoproliferative lesions were in the anterior orbit (extraconal) while the majority of the vascular and neurogenic lesions arose intraconally.…”

Differential diagnosis of thyroid orbitopathy — diseases mimicking the presentation or activity of thyroid orbitopathy

“…According to the authors, the most common primary malignant orbital tumour is Lymphoma malignum followed by melanoma malignum, carcinoma anaplasticum, carcinoma planoepitheliale, adenocarcinoma, and tumour mixtus malignus. Malignant lymphoma was detected in 11.47% of patients [51].…”

“…Orbital tumours are divided into primary tumours arising from orbital tissues, tumours penetrating the orbital cavity from surrounding tissues, and metastases from other parts of the body. The main symptom is exophthalmos, reduction of eye movement with or without double vision, swelling and redness of the eyelids, and conjunctiva [50,51].…”

“…The group of benign orbital tumours includes tumour mixtus, haemangioma, meningioma meningioma meningotheliale, neurinoma and glioma nervi optici, neurofibromata, lipoma, fibroma, and osteoma. According to the authors, the most common benign tumour is haemangioma followed by tumour mixtus and meningioma meningioma meningotheliale [50,51].…”