Primary Osteosarcoma of the Rib Identified on Bone Scintigraphy

Xie, Peng; Huang, Jianmin

doi:10.1097/rlu.0000000000001106

Cited by 4 publications

(4 citation statements)

References 16 publications

(12 reference statements)

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“…Wide en bloc resection with negative margins is necessary in all cases of malignant chest wall tumours including osteosarcoma but neoadjuvant chemotherapy may be considered in cases where in the pre-operative diagnosis of osteosarcoma is established. 7,8 The overall prognosis of osteosarcoma in flat bones remains despite aggressive surgery and multi-agent chemotherapy; previous study reported a 5-year survival of only about 27%. 9…”

Section: Discussionmentioning

confidence: 99%

An unusual occurrence of giant primary osteosarcoma of chest wall in adult: case report and review of literature

et al. 2019

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<p class="abstract">Osteosarcoma is most frequently occurring bone malignancy which commonly occurs in the ends of the long bone. Usually osteosarcomas do not involve the bones of the chest wall. 22 year old patient presented with swelling in left anterior chest wall gradually enlarging over the period of 1 year accompanied by dull aching pain in the same. On examination there was 30×25 cm large hard irregular swelling which was fixed to chest wall. CECT Thorax was suggestive of 30×25×18 cm sized soft tissue lesion involving 3, 4, 5 rib involvement with sunburst periosteal reaction. Mass is having large extrathoracic with small intrathoracic extensions. Moderate pleural effusion was noted. Core biopsy of mass identified the tumor as osteosarcoma. Primary malignant bone tumors of the chest wall are very rare entity. Of these tumors chondrosarcomas are the most frequent. Chondrosarcoma are chemo-resistant as compared to osteosarcomas. Management of such tumors should follow the same oncological principles of resection with wide margins whenever possible. Neoadjuvant chemotherapy may be given in cases of responsive etiologies like Ewing sarcoma or osteosarcoma. These malignancies generally have poor prognosis.</p><p class="abstract"> </p>

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Section: Discussionmentioning

confidence: 99%

An unusual occurrence of giant primary osteosarcoma of chest wall in adult: case report and review of literature

et al. 2019

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“…There are no characteristic symptoms or signs of osteosarcoma of the ribs; in fact, primary osteosarcomas originating from flat bones often pose a major diagnostic challenge to the treating clinicians [5,6]. The typical 'sunburst' radiological pattern observed in the osteosarcomas of the long bones is generally not observed in osteosarcomas of the ribs and other flat bones.…”

Section: Discussionmentioning

confidence: 99%

“…Bone scans are useful in excluding multifocal disease and occasionally skip lesions. Skip lesions are however most reliably identified by a MRI scan [5].…”

Section: Discussionmentioning

confidence: 99%

“…The guidelines for management of a rib primary osteosarcoma is not clear due to the small number of cases studied. Wide en bloc resection aimed at achieving tumour-free margins is necessary in all cases of malignant chest wall tumours including osteosarcomas [5]. Surgery for primary rib osteosarcomas should include resection of the involved ribs with wide margins that may include the adjacent ribs, intercostal muscles and pleura as clinically indicated.…”

Section: Discussionmentioning

confidence: 99%

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The Management Challenges in an Unusual Case of Primary Osteosarcoma of the Rib in an Adult Patient

Arulmolichelvan

2017

Indian J Surg

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Primary osteosarcomas are derived from primitive bone-forming mesenchymal stem cells and most often originate in the metaphysis of the long bones of children and adolescents, but it occurs very rare in adults. Approximately 10% of osteosarcomas are located in the flat bones, pelvis being the main site. Involvement of flat bones like rib may be seen as a metastatic process or secondary to chemotherapy, but a primary osteosarcoma rib is extremely rare. Osteosarcoma originating from such rare sites poses numerous diagnostic and therapeutic challenges, and we report one such case in a 24-year-old male patient. Our case highlights the fact that osteosarcoma of the rib, although rare, should be considered in the differential diagnosis of primary malignant neoplasms of the rib even in the adult population. Further, early prompt diagnosis and aggressive multimodality management are cornerstones of management and will help improve the survival outcomes.

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Solitary Thumb Acrometastasis Identified on Bone Scintigraphy

Xie

Huang²

2017

Clinical Nuclear Medicine

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A 45-year-old man with a history of adenocarcinoma in the right lung 3 years ago underwent a Tc-MDP bone scan to evaluate possible osseous metastasis. The images demonstrated intense activity in the region of left thumb, while the tracer uptakes in other bones were not typical of metastases. A CT of the hand showed diffuse sclerotic changes with destructed trabecular structure in the proximal phalanx of the left thumb. The left thumb was subsequently resected, and the pathological examination of the resected left first metacarpal bone confirmed the diagnosis of metastasis of lung adenocarcinoma.

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Primary Osteosarcoma of the Rib Identified on Bone Scintigraphy

Cited by 4 publications

References 16 publications

An unusual occurrence of giant primary osteosarcoma of chest wall in adult: case report and review of literature

An unusual occurrence of giant primary osteosarcoma of chest wall in adult: case report and review of literature

The Management Challenges in an Unusual Case of Primary Osteosarcoma of the Rib in an Adult Patient

Solitary Thumb Acrometastasis Identified on Bone Scintigraphy

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