Primary Packaging and Stability Evaluation of a Serum Used for the Periorbital Area of the Sensitive Eye

Abstract

The aim of this study was the development and formulating of an eye contour serum containing hyaluronic acid (HA) and the assessment of stability tests performed for the cosmetic product, transfered into a glass cosmetic bottle with polipropylene (PP) pump and cap. Sample of cosmetic serum were stored using 20 mL glass bottles with PP (Polypropylene) pump and cap. The developed cosmetic formulation was monitored under accelerated stability studies, performed over a period of 30 days while maintaining the product at 4, 20 and 40�C. Quality control initial, and after initiating the accelerated stability test was performed for the developed cosmetic formulation.

Advantages of Hyaluronic Acid and Its Combination with Other Bioactive Ingredients in Cosmeceuticals

“…Hyaluronic acid (HA) is a polysaccharide belonging to the glycosaminoglycans, made up of disaccharide units constituted of N-acetylglucosamine and D-glucuronic acid ( Figure 1 ). It is a component of the connective, epithelial, and neural tissues and it represents a substantial constituent of the extracellular matrix (ECM) [ 1 , 2 , 3 , 4 , 5 , 6 ]. HA was discovered for the first time in the vitreous humour of the eye in 1934, and in 1964 it was synthesized in vitro [ 7 , 8 , 9 ].…”

A New, Rapid and Efficient HPLC Method to Assay Resveratrol in Food Supplements

“…Resveratrol has been the subject of intense interest in recent years due to a range of unique anti-aging properties.These include cardiovascular benefits via increased nitric oxide production, down-regulation of vasoactive peptides, lowered levels of oxidized low-density lipoprotein, and cyclooxygenase inhibition; possible benefits on Alzheimer disease by breakdown of betaamyloid and direct effects on neural tissues; phytohormonal actions; anticancer properties [6]. and on the other hand, due to its antioxidant effects, in the manufacturing of cosmetic products, industry which increasingly focuses on the development of active cosmetics [9,10].…”

Selection and Application of Synthetic versus Natural Emollients in the Formulation of Skin Care Products

“…Cosmetics are commercially available products, that are used to improve the appearance of the skin [1][2][3][4]. Firstly, for a developed cosmetic formula to fulfill all the requirements, it is necessary to have a suitable vehicle (that encompasses emollients, moisturizers, preservatives, perfumes, colorants) and to include in its formulation all the active ingredients (UV filters, botanical or biotechnological extracts), necessary to attain what is claimed by its advertising [5][6][7][8][9][10][11].…”