Primary paraganglioma located between the thyroid gland and the left common carotid artery: A case report

Huang, Dihua; Huang, Liming; Tian, Ju; Sun, Aihua; Xu, Feng

doi:10.3892/ol.2014.2432

Cited by 3 publications

(8 citation statements)

References 16 publications

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“…These tumors are categorized as symptomatic or asymptomatic based on whether endogenous catecholamine hormone excretion is elaborated. CT, CT angiography, MRI, and PET/CT have been found useful for the diagnosis of the disease [ 1 , 2 ]. Specifically, Ga-labelled somatostatin agonist PET is favored regardless of the patient's genetic background [ 13 ].…”

Section: Discussionmentioning

confidence: 99%

“…Specifically, Ga-labelled somatostatin agonist PET is favored regardless of the patient's genetic background [ 13 ]. Fine-needle biopsy plays an elusive role in the diagnosis of paragangliomas, and cytology is non-diagnostic most of the time [ 2 , 6 ].…”

Section: Discussionmentioning

confidence: 99%

“…Paragangliomas are highly vascularized tumors that emanate from the paraganglia of neural crest cells and appear commonly in the head and neck region; they are classified as symptomatic or asymptomatic based on their ability of endogenous hormone secretion [1,2]. They usually occur in the carotid body [3][4][5][6][7], jugulotympanic area [8][9][10][11][12], and vagal paraganglia [4,13]; they are also found in other regions in the head and neck such as the thyroid [2,3,6,10], nasal cavity [11], endolarynx [12], and supraclavicular fossa [1].…”

Section: Introductionmentioning

confidence: 99%

“…Most paragangliomas include neurosecretory granules and appear as a painless asymptomatic mass, although 1-3% of them may be symptomatic and may clinically manifest symptoms resembling those of a pheochromocytoma due to catecholamine secretion [ 4 ]. Positron emission tomography (PET)/CT has been highlighted as useful in the diagnosis of paragangliomas; however, immunohistochemistry remains the gold standard of the primary diagnostic method [ 2 ]. Fine-needle aspiration (FNA) biopsy is commonly non-diagnostic for these tumors and can be misleading and may lead to the condition being misinterpreted as medullary thyroid cancer [ 6 ].…”

Section: Introductionmentioning

confidence: 99%

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A Paraganglioma in the Right Supraclavicular Fossa: Mistaken for a Thyroid Mass

Νικολόπουλος¹,

Ploumidou²,

Sourla³

et al. 2021

Cureus

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Paragangliomas are rare lesions of the endocrine system that can be treated either by embolization preoperatively followed by surgical excision or by surgical excision or radiotherapy. In this report, we present an extremely rare location of a nonfunctional paraganglioma in the head and neck region, located in the right supraclavicular fossa, which was misdiagnosed as a thyroid tumor, in a 72-year-old female patient. Imaging revealed a 2.5 × 4.5 × 2 cm well-defined vascularized mass. Fine-needle aspiration (FNA) on the tumor was not diagnostic initially; however, a third attempt revealed thyroid cells suggesting the existence of an ectopic thyroid tumor. FNA was additionally performed on the right thyroid lobe, revealing atypical follicular colloid cells of the Bethesda 3 category. Therefore, the excision of the ectopic thyroid tumor along with right lobectomy was planned. No embolization was initiated preoperatively in this case. Histopathology revealed that the supraclavicular mass was a paraganglioma. Paragangliomas supplied by the subclavian, innominate, and common carotid artery are rarely reported, and to our knowledge, this is the third case to be reported worldwide.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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A Paraganglioma in the Right Supraclavicular Fossa: Mistaken for a Thyroid Mass

Νικολόπουλος¹,

Ploumidou²,

Sourla³

et al. 2021

Cureus

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“…Atualmente não há evidências histológicas para distinguir os paragangliomas entre benignos e malignos, porém algumas características têm sido usadas para prever uma possível malignidade, como a invasão vascular e a ausência do marcador imunohistoquímico S-100 5,12 . Características estas encontradas no caso clínico apresentado.…”

Section: Discussionunclassified

Paraganglioma Invasor, Produtor de Metanefrinas e Indutor de Síncopes Progressivas

Hoffmann¹,

Takeshita²,

Nascimento³

et al. 2018

jbnc

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Introdução: Paragangliomas são tumores raros, vasculares e predominantemente benignos, de origem embriológica da crista neural. Em sua grande maioria são assintomáticos e, quando acometem a cabeça e pescoço, o local mais comum é o corpo carotídeo. Raramente podem induzir síncopes, invadir vasos adjacentes e produzir metanefrinas. Caso Clínico: Mulher com 26 anos e síncopes progressivas há dois anos, com frequência crescente até dois episódios diários, associados a bradicardia e hipotensão. Foi diagnosticado paraganglioma carotídeo invasivo e produtor de metanefrinas. A exérese do paraganglioma controlou as crises e resultou em um retorno aos níveis basais de metanefrinas. Após dois anos de seguimento a paciente encontra-se assintomática. Discussão: Neste caso foi apresentado um tumor de seio carotídeo raro, de crescimento lento, que se apresentou clinicamente com síncopes progressivas, de características reflexas, neuro-mediadas, pela compressão do seio carotídeo e de forma atípica, pela produção de metanefrinas. As características deste tumor foram revistas, assim como seus fenômenos fisiopatológicos peculiares e suas recomendações de acompanhamento pós-operatório, embasados nos Guidelines europeus atuais. Conclusão: Paragangliomas de corpo carotídeo, que são considerados tumores raros, podem apresentar-se com características ainda mais incomuns, necessitando, como neste caso, de um conhecimento mais apurado sobre síncopes e paragangliomas. A definição de síncopes progressivas é inexistente na literatura científica atual, podendo ser classificadas como um grupo à parte, merecendo abordagem diagnóstica efetiva mais precocemente, associada a desfechos com menor risco, mais breves e favoráveis.

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Paraganglioma, Thyroid

Nosé¹

2018

Diagnostic Pathology: Endocrine

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Primary paraganglioma located between the thyroid gland and the left common carotid artery: A case report

Cited by 3 publications

References 16 publications

A Paraganglioma in the Right Supraclavicular Fossa: Mistaken for a Thyroid Mass

A Paraganglioma in the Right Supraclavicular Fossa: Mistaken for a Thyroid Mass

Paraganglioma Invasor, Produtor de Metanefrinas e Indutor de Síncopes Progressivas

Paraganglioma, Thyroid

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