Primary plasma-cell tumors of the upper air passages and oral cavity

Stout, Arthur Purdy; Kenney, Francis R.

doi:10.1002/1097-0142(194903)2:2<261::aid-cncr2820020206>3.0.co;2-k

Cited by 103 publications

(21 citation statements)

References 28 publications

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“…l t l h icentric disease. Supporting evidence includes: 1) the frequent finding of partial node replacement in a manner similar to other metastatic tumors, 2) the usual involvement of ipsilateral cervical nodes when the primary 30% of cases~4.7.10,13,19,20 Most aUthors438, 16,19,20 ably represents metastasis from the v-i,-iar Y Vol. 42 neoplasm is clearly lateralized and 3) the failure to demonstrate tumor in other lymph node chains.…”

Section: Discussionmentioning

confidence: 99%

Nonepithelial tumors of the nasal cavity, paranasal sinuses and nasopharynx. A clinicopathologic study. IX. Plasmacytomas

Perzin

Pushparaj

1978

Cancer

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Plasmacytomas occasionally may arise in extraosseous sites, of which the upper respiratory tract is the most common. In our series of 256 nonepithelial tumors involving the nasal cavity, paranasal sinuses and nasopharynx, 10 (4%) were apparently primary extramedullary plasmacytomas. Of our patients with adequate follow-up information, four died of disseminated disease 2, 4, 5 and 6 years after the initial diagnosis. One was alive 6 years after diagnosis with locally persistent tumor. Another was living without recurrence 12 years later. Based on our findings and on the cases reported in the literature, extramedullary plasmacytomas arising in the head and neck area may evolve into one of several different patterns. 1) Some patients have localized disease which is apparently controlled (by surgery, radiotherapy or both) and which never recurs locally or becomes disseminated. 2) In some cases, the tumor recurs locally and is controlled by further therapy. 3) Other patients have a locally persistent and aggressive lesion which cannot be eradicated and which eventually leads to the patient's death by uncontrolled local growth. 4) Still other patients eventually develop evidence of plasma cell neoplasms elsewhere in the body and/or multiple myeloma.

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Section: Discussionmentioning

confidence: 99%

Nonepithelial tumors of the nasal cavity, paranasal sinuses and nasopharynx. A clinicopathologic study. IX. Plasmacytomas

Perzin

Pushparaj

1978

Cancer

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“…A poor prognosis is not necessarily the case for those with primary extramedullary plasmacytomas as it is impossible to forecast which of these will develop generalised disease. Some cases have been followed for more than 10 years without recurrence or dissemination (Jaegar, 1941;Figi, Bryders and Havens, 1945;Stout and Kenney, 1949;Dolin and Dewar, 1956). …”

Section: Discussionmentioning

confidence: 99%

The late appearance of extramedullary lesions in myelomatosis.

Craft¹

1967

Br J Cancer

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“…The age at presentation is similar in multiple myeloma and extramedullary plasmacytoma; 75 per cent. between the 5th and 7th decades (Stout and Kenny, 1949;Webb et al, 1962;Todd). The male to female ratio of the solitary plasmacytoma group (in bone and extramedullary sites) is 4 : 1 as compared with 9 : 7 in the multiple myeloma group (Stout and Kenny ; Innes and Newall; Webb; Todd).…”

Section: Extramedullary Plasmacytoma Where the Primary Focus Commencementioning

confidence: 98%

“…Tumour imprints of fresh tissue, air-dried and stained with Wright's stain, readily produce the fine cytological details of myeloma cells as seen in aspirated bone marrow (Webb et al). However, the presence of numerous plasma cells need not indicate a plasma cell tumour, but may be an inflammatory condition (Stout and Kenny;Ackerman, 1968;More et al). In the breast, plasma cell mastitis (Adair, 1933) also called mammary duct ectasia (Haagensen, 1971) should be excluded.…”

Section: Extramedullary Plasmacytoma Where the Primary Focus Commencementioning

confidence: 99%

Extramedullary plasmacytoma of the breast

Proctor

Rippey

Shulman

et al. 1975

The Journal of Pathology

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The clinical and histopathological features of a case of solitary extramedullary plasmacytoma of the breast are described. After 46 mth of follow-up, there has been no recurrence of the tumour, and no evidence of further extramedullary plasmacytomas, multiple myeloma or diffuse myelomatosis either clinically, radiologically or on biochemical and haematological investigations. She has developed diabetes mellitus. Distinction is made between the true extramedullary plasmacytoma and those which are a manifestation of multiple myeloma. The unpredictable behaviour and prognosis of extramedullary plasmacytomas is indicated.

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Primary plasma-cell tumors of the upper air passages and oral cavity

Cited by 103 publications

References 28 publications

Nonepithelial tumors of the nasal cavity, paranasal sinuses and nasopharynx. A clinicopathologic study. IX. Plasmacytomas

Nonepithelial tumors of the nasal cavity, paranasal sinuses and nasopharynx. A clinicopathologic study. IX. Plasmacytomas

The late appearance of extramedullary lesions in myelomatosis.

Extramedullary plasmacytoma of the breast

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