Primary Pulmonary Choriocarcinoma

Abstract

We present a case of a 25-year-old Hispanic woman who presented to emergency department with chief complaint of left lower quadrant abdominal pain. Initial workup revealed positive pregnancy test. Serum human chorionic gonadotropin was 36,478 (normal range, 0 to 8.0) IU/mL. She underwent diagnostic laparoscopy with dilatation and curettage, which did not reveal any evidence of intrauterine or extrauterine pregnancy. Chest and abdomen radiographic findings were significant for a heterogenously enhancing 2.2×1.7×1.6 cm nodule in superior segment of the right lower lobe of the lung and a large perinephric hematoma. We performed radial endobronchial ultrasound-guided transbronchial biopsies of the right lower lobe lesion. Pathologic specimen revealed choriocarcinoma.

Omental choriocarcinoma masquerading pregnancy of unknown location: A case report

“…Most cases of choriocarcinoma are intrauterine and of gestational origin. Extrauterine choriocarcinoma is quite rare, few case reports are present in the literature ( 4 , 5 , 6 , 7 , 8 , 9 , 10 , 11 , 12 ). Moreover, choriocarcinoma of the greater omentum is extremely rare, with only two cited cases ( 8 , 11 ).…”

“…In the case of primary extrauterine choriocarcinoma, the uterus, tubes, and ovaries show no evidence of pregnancy. On reviewing the literature, four cases of primary choriocarcinoma could be elucidated occurring on the left anterior abdominal wall of the pelvis ( 9 ), on the surface of a subserosal uterine leiomyoma ( 10 ), in the omentum ( 11 ), and the right lower lobe of the lung ( 12 ). All these cases were managed by complete resection of tumor ± adjuvant chemotherapy.…”