Primary pulmonary hypoplasia: A case report and review of the literature

Odd, D E; Battin, Malcom; Hallam, Lavinia; Knight, David B.

doi:10.1046/j.1440-1754.2003.00191.x

Cited by 15 publications

(11 citation statements)

References 17 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Respiratory distress in the first five minutes following birth is typical for these patients, and they usually require mechanical ventilation. Apgar scores are usually found to be lower, although babies with completely normal Apgar scores may also be seen [11,[15][16][17][18][19]. However, as in our patient, patients who remain asymptomatic until puberty have also been reported [7,9,10].…”

confidence: 53%

“…Pulmonary hypoplasia is characterized by reduced and/or less developed lung tissue to varying degrees [7][8][9][10]. When pathologic specimens of the patients with pulmonary hypoplasia were examined, it was found that ratio of lung weight/body weight of the patients was less than 0.012 [11]. Development of bronchial tree occurs in 26th to 31st days of intrauterine life.…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

A rare clinical presentation of pulmonary hypoplasia

Gülen¹,

Kar²,

Midyat³

et al. 2011

OJPed

View full text Add to dashboard Cite

Pulmonary hypoplasia is a rare congenital anomaly, which is frequently associated with other congenital anomalies. Clinical symptoms vary depending on the other system anomalies and severity of pulmonary hypoplasia. Although it is usually diagnosed in infancy and childhood, some cases do not show any symptoms until the adolescent ages. In adolescents and adults with unilateral hypolucent lung, although it is seen rarely, pulmonary hypoplasia should always be kept in mind. In this article, we present a case with pulmonary hypoplasia who remained asymptomatic until puberty

show abstract

confidence: 53%

Section: Discussionmentioning

confidence: 99%

A rare clinical presentation of pulmonary hypoplasia

Gülen¹,

Kar²,

Midyat³

et al. 2011

OJPed

View full text Add to dashboard Cite

show abstract

“…It may be caused by an embryologic defect of the lung or vascular tissues, as in congenital acinar dysplasia [6,7] or by an in utero vascular accident. Only a few cases of primary unilateral pulmonary hypoplasia have been described in the literature with varying degrees of severity ranging from complete hypoplasia of one lung to simple hypoplasia of an isolated lobe [1,5,6,8,9], including in familial series [3,4].…”

Section: Discussionmentioning

confidence: 99%

“…Unilateral pulmonary hypoplasia or agenesis is a rare cause of respiratory distress in the neonate [1,8,9]. Most cases are secondary to conditions that limit fetal lung growth such as diaphragmatic hernia or bronchial stenosis.…”

Section: Introductionmentioning

confidence: 99%

Imaging of primary unilateral pulmonary hypoplasia: a case report

et al. 2008

View full text Add to dashboard Cite

show abstract

“…1), the result of abnormal antenatal lung growth, is common, being present in 15 to 20% of early neonatal deaths. It may be primary [1], but more usually occurs secondary to a variety of insults which can be largely divided into those which reduce intra-thoracic space, fetal breathing movements or amniotic fluid volume. It is also found in association with trisomy 18 and 21 [2].…”

Section: Introductionmentioning

confidence: 99%

Prediction and Prevention of Abnormal Antenatal Lung Growth

Prendergast¹,

Greenough

2007

CRMR

View full text Add to dashboard Cite

Pulmonary hypoplasia, the result of abnormal antenatal lung growth, occurs as a primary anomaly or more usually the consequence of disorders resulting in reduction of amniotic fluid volume, intra-thoracic space or fetal breathing movements. Two dimensional (2D) ultrasound examination yields useful information on amniotic fluid volume and the presence of congenital abnormalities associated with pulmonary hypoplasia. Assessment of the thoracic or lung size by 2D ultrasound examination, is insufficiently specific, but a very low lung to head ratio predicts a fatal outcome in fetuses with congenital diaphragmatic hernia (CDH). Three-D ultrasound examination provides information on fetal lung volume prior to 34 weeks of gestation but can be inaccurate if there is oligohydramnios. Magnetic resonance imaging is expensive and has limited patient acceptability. Antenatal interventions attempted to prevent pulmonary hypoplasia include amnioinfusion, which can facilitate ultrasound examination, but only temporarily relieves oligohydramnios. Thoraco-amniotic shunting results in effective drainage of pleural effusions, facilitating resuscitation, but is usually performed too late in pregnancy to influence lung growth. In utero surgical repair of CDH has been attempted, but a more promising technique is obstruction of the normal egress of fetal lung fluid by placing a balloon in the trachea.

show abstract

Primary pulmonary hypoplasia: A case report and review of the literature

Cited by 15 publications

References 17 publications

A rare clinical presentation of pulmonary hypoplasia

A rare clinical presentation of pulmonary hypoplasia

Imaging of primary unilateral pulmonary hypoplasia: a case report

Prediction and Prevention of Abnormal Antenatal Lung Growth

Contact Info

Product

Resources

About