Primary Renal Carcinoid Tumor With Multiple Metastases

Chiang, Mae-Hee; Ou, Yen-Chen; Yang, Chi‐Rei; Cheng, Chen-Li; Ho, Hao-Chung

doi:10.1016/s1726-4901(10)70093-9

Cited by 6 publications

(5 citation statements)

References 6 publications

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“…Although the majority of patients in previous reports were diagnosed with either local or distant metastatic disease at the time of initial diagnosis, most patients were asymptomatic and demonstrated prolonged survival. The most common site for metastatic is regional lymph nodes, other locations include liver [ 1 , 5 ], bone [ 6 , 7 ] and lung [ 1 ]. The previous literature report liver metastatic disease at the time of surgery, only two patients developed liver metastases within 5 and 6 months of surgery [ 1 , 4 ].…”

Section: Discussionmentioning

confidence: 99%

Renal carcinoid tumor with liver metastasis followed up postoperatively for 9 years

Ouyang

Yan

et al. 2015

Diagn Pathol

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BackgroundWe describe a case of renal carcinoid tumor with liver metastasis followed up postoperatively for 9 years.Case presentationA 33-year-old man presented with left flank dull ache. On the abdominal computed tomography, a solid renal mass in the upper portion of the left kidney was detected. The patient had no other abnormal findings, such as suspected distant metastasis or lymph node metastasis. Radical nephrectomy was performed on 14/9/2005. Histological examination and immunohistochemical staining confirm primary renal carcinoid tumor. 9 years after radical nephrectomy, computed tomography of the abdomen demonstrated a 2 cm × 1.8 cm cyst mass in the right liver. Similar pathologic characteristics were found between the renal carcinoid tumor and liver tumor.ConclusionsWe present a primary renal carcinoid tumor with liver metastasis 9 years after radical nephrectomy. With literature review, renal carcinoid tumors exhibit heterogenous behavior.

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Section: Discussionmentioning

confidence: 99%

Renal carcinoid tumor with liver metastasis followed up postoperatively for 9 years

Ouyang

Yan

et al. 2015

Diagn Pathol

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“…reported a case of renal carcinoid with extensive hepatic metastases, in which tumor resection with para-aortic lymph node dissection was followed a year later by transarterial embolization of hepatic metastases, and noted a good outcome. 22 The use of octreotide for the treatment of functional and nonfunctional NET prolonged time to progression in the PROMID study, 23 although there are few publications about the experience with octreotide in renal carcinoid tumors. Korkamaz et al .…”

Section: Discussionmentioning

confidence: 99%

Neuroendocrine Tumors of the Kidney: A Single Institution Experience

Teegavarapu

Rao

Matrana

et al. 2014

Clinical Genitourinary Cancer

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Background Renal neuroendocrine tumors (NET), comprising carcinoid tumors and small cell carcinomas, are a rare group of neoplasms. The rarity of these tumors poses a diagnostic and therapeutic challenge. Our purpose was to characterize the cases treated at a tertiary cancer center and to evaluate patients' outcomes with the available treatment modalities. Methods This is a retrospective study of patients with renal NET seen at The University of Texas MD Anderson Cancer Center between January 1, 2001, and January 1, 2011. Patient and tumor data were analyzed by descriptive statistical methods. Results Three cases of carcinoid tumors and six cases of small cell carcinoma were identified. The median age at diagnosis was 53 years for patients with carcinoid and 65 years for patients with small cell carcinoma. The most common presenting symptoms were back pain, flank pain, and hematuria. The morphological appearance of the tumor cells and their immunohistochemical reactivity for neuroendocrine markers and cytokeratin helped establish the diagnosis. Nephrectomy was the mainstay of treatment for carcinoid tumors, yielding good long-term results, even in the presence of metastases. Surgery and chemotherapy were utilized for small cell carcinoma of the kidney. The median overall survival for patients with small cell carcinoma of the kidney was 17.3 months. Conclusion Renal carcinoid tumors are indolent and are associated with prolonged survival, while small cell carcinomas of the kidney are aggressive tumors with relatively short overall survival. Although palliative in nature, cytotoxic chemotherapy is the mainstay of therapy and is best given before surgery.

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“…The clinical presentation is similar to other renal neoplasms. The most commonly reported presenting complaint was abdominal or flank pain [9, 10, 12, 15–17, 19, 21, 22, 26–30]. Other symptoms include haematuria [8, 11, 18, 24] constipation, urinary frequency, fever, epigastric discomfort, weight loss, and abdominal mass [17, 19, 24, 25, 27, 28, 30, 31] which is similar to other research findings [36, 51–53].…”

Section: Discussionmentioning

confidence: 99%

Primary Carcinoid Tumour of the Kidney: A Review of the Literature

Omiyale

Venyo

2013

Advances in Urology

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Context. Primary renal carcinoid tumours are rare. Their pathogenesis is unknown and the clinical presentation is similar to other renal tumours thus posing diagnostic dilemmas for clinicians. Objectives. To review the literature for case reports of primary renal carcinoids. Methods. Literature was extensively searched for case reports for primary renal carcinoids. Reports of metastatic carcinoids to the kidneys were excluded. Results. Approximately less than 90 cases of primary carcinoid tumours of the kidney have been reported in the literature. A total of 29 cases of primary renal carcinoids were reviewed. The mean age of presentation was 48 years (range 29–75) with both right kidney (48.3%) and left kidney (44.8%) being equally affected. 28.6% of the cases reviewed were diagnosed as an incidental finding. The mean followup time was 20 months with 73.1% of patients without evidence of disease after surgical treatment (radical or partial nephrectomy). Primary carcinoid tumours of the kidney are often well differentiated tumours. They are often misdiagnosed because of their rarity and similar presentation with other renal tumours. Conclusions. Primary carcinoid tumours of the kidney are rare tumours with an indolent course with frequent metastasis. Metastatic work up and followup is required in their management.

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Primary Renal Carcinoid Tumor With Multiple Metastases

Cited by 6 publications

References 6 publications

Renal carcinoid tumor with liver metastasis followed up postoperatively for 9 years

Renal carcinoid tumor with liver metastasis followed up postoperatively for 9 years

Neuroendocrine Tumors of the Kidney: A Single Institution Experience

Primary Carcinoid Tumour of the Kidney: A Review of the Literature

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