Primary squamous carcinoma of the proximal large bowel

Lyttle, J. A.

doi:10.1007/bf02562498

Cited by 34 publications

(17 citation statements)

References 12 publications

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“…Generally, the treatment is based on that for adenocarcinomas, which is predominantly surgery combined with chemotherapy and radiotherapy. With the advances in chemotherapy and radiotherapy, the accuracy of determining stage and evaluating response, a multitude of recent studies utilizing various treatment regimens have been reported, which included 5-fluorouracil (5FU)/mitomycin C, 5FU, 5FU/cisplatin, capecitabine/cisplatin, capecitabine, raltitrexed/oxaliplatin and S-1 (10,11,.…”

Section: Discussionmentioning

confidence: 99%

Gemcitabine-based chemotherapy in colon squamous cell carcinoma: A case report and literature review

Zhao

Guo

Sun

et al. 2017

Molecular and Clinical Oncology

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Abstract. Squamous cell carcinoma (SCC) originating from the colon is rare. In terms of its clinicopathological characteristics, this type of cancer has been reported to be more aggressive and have a worse prognosis compared with adenocarcinoma. We herein present a successful therapeutic approach applying neoadjuvant and adjuvant gemcitabine-based chemotherapy in a patient with colon SCC. A 58-year-old male patient received two cycles of neoadjuvant chemotherapy with a regimen including gemcitabine, oxaliplatin and capecitabine, followed by radical excision and six cycles of adjuvant chemotherapy. Contrast-enhanced computed tomography and serum tumor markers were used for reassessment and evaluation was based on the World Health Organization criteria. Following neoadjuvant chemotherapy, the mass had shrunk and the patient was classed as having stable disease. Surgery and adjuvant chemotherapy were then performed and the patient had achieved a progression-free survival of 10 months when this report was submitted. Therefore, gemcitabine may be a treatment option for colon SCC in the neoadjuvant and/or adjuvant chemotherapy setting.

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Section: Discussionmentioning

confidence: 99%

Gemcitabine-based chemotherapy in colon squamous cell carcinoma: A case report and literature review

Zhao

Guo

Sun

et al. 2017

Molecular and Clinical Oncology

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“…En faveur de cette seconde hypothèse, l'association fréquente du CE colorectal à des colites inflammatoires chroniques, en particulier la rectocolite ulcérohémorragique, l'incidence relative de cette association étant de 1,7 % alors qu'elle est seulement de 0,25 à 0,5 ‰ dans la population générale [8]. Des colites parasitaires telles que l'amibiase ou la schistosomiase ainsi que des fistules colocutanées chroniques égale-ment décrites pourraient être à l'origine de la métaplasie malpighienne [1][2][3]5,6].…”

Section: Discussionunclassified

“…L'histogenèse d'une telle tumeur ainsi que son potentiel évolutif soulèvent encore des interrogations. Par ailleurs, le CE colique s'associe fréquemment à des adénocarcinomes synchrones et métachrones coliques et extracolique [1][2][3][4][5].…”

Section: Introductionunclassified

Carcinome épidermoïde primitif du côlon: à propos d’un cas exceptionnel associé à un adénocarcinome gastrique

Daldoul

Moussi

Zaouche

2011

J Afr Hepato Gastroenterol

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Le carcinome épidermoïde (CE) primitif du côlon est une tumeur exceptionnelle. Seuls 52 cas ont été publiés dans la littérature anglo-saxonne entre 1927 et 2001. Outre sa rareté, il se distingue par son association fréquente avec d'autres néoplasies digestives et extradigestives. Nous rapportons l'observation d'un patient de 74 ans ayant un CE du côlon associé à un adénocarcinome gastrique. Les deux tumeurs ont été découvertes à la suite d'une intervention pour un abcès périnéoplasique du côlon. À la lumière de cette observation insolite, qui, à notre connaissance, est unique, les auteurs discutent les particularités anatomocliniques et thérapeutiques ainsi que les hypothèses étiopatho-géniques de cette entité peu commune. Pour citer cette revue : J. Afr. Hépatol. Gastroentérol. 5 (2011). Mots clés Cancer colique · Carcinome épidermoïde · Cancer gastriqueAbstract Primary squamous cell carcinoma of the colon is an exceptional tumor. Only 52 cases have been published in the English literature between 1927 and 2001. Besides its rarity, it is distinguished by its frequent association with other gastrointestinal and extra-digestive malignancies. We report the case of a 74-year-old patient with squamous cell carcinoma of the colon associated with gastric adenocarcinoma. Both tumors were discovered after surgery for an intra-abdominal abscess. By means of this unusual case, the authors discuss the etiopathogenic hypotheses and the therapeutic management of this uncommon entity.

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“…[17] Because of the rarity of this malignancy, the role of chemoradiation has not been clearly defined. [101819] The prognosis is similar to rectal adenocarcinoma for Stage I and II node-negative disease; however, nodal involvement is associated with a worse prognosis than adenocarcinoma of a similar stage. [7] Adjuvant chemotherapy or chemoradiation, although unproven, should be considered in conjunction with surgical resection.…”

Section: Discussionmentioning

confidence: 99%

“…[1] It was first described in 1919 by Schmidtmann. [2] Based on previous case reports, other conditions have been associated with this rare malignancy, such as colocutaneous fistula,[3] prior radiation,[45] ulcerative colitis,[6–8] schistosomiasis,[9] ovarian cancer,[4] ovarian teratoma,[10] endometrial carcinoma,[11] human papilloma virus (HPV)[12] and colonic duplication. [1314] Previously reported cases of SCC with a history of radiotherapy have involved brachytherapy for the treatment of prostate cancer[5] and for the treatment of ovarian adenocarcinoma.…”

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confidence: 99%

Squamous cell carcinoma of the rectum 21 years after radiotherapy for cervical carcinoma

Leung

Heitzman

Madan

2009

Saudi J Gastroenterol

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Squamous cell carcinoma (SCC) of the rectum is an extremely rare malignancy, accounting for 0.1-0.2% of rectal malignancies. It is associated with ulcerative colitis, prior radiation, schistosomiasis, ovarian cancer, endometrial cancer, human papilloma virus, colocutaneous fistulas and colonic duplication. Prior reported cases of SCC of the rectum have involved treatment with brachytherapy and external beam radiation. This case is particularly interesting because of the remote exposure of radiation (21 years previously) and the subsequent development of SCC of the rectum. Although extremely rare, SCC of the rectum can occur decades after radiation exposure.

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Primary squamous carcinoma of the proximal large bowel

Abstract: A patient with primary squamous carcinoma of the proximal colon, who also had a previous adenocarcinoma of the large bowel, is described along with a review of the literature. Clinical features, etiologic factors, and possible pathogenesis are discussed.

Cited by 34 publications

References 12 publications

Gemcitabine-based chemotherapy in colon squamous cell carcinoma: A case report and literature review

Gemcitabine-based chemotherapy in colon squamous cell carcinoma: A case report and literature review

Carcinome épidermoïde primitif du côlon: à propos d’un cas exceptionnel associé à un adénocarcinome gastrique

Squamous cell carcinoma of the rectum 21 years after radiotherapy for cervical carcinoma

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