Primary thyroid lymphoma- case series of patients from a developing country

Abstract

Primary Thyroid Lymphoma (PTL) is a rare disease, mostly affecting middle-to-old aged females. It has a strong association with pre-existing thyroiditis, which increases the risk of its development. The disease has been studied in detail in the Western populations. However, there is lack of data for south Asians, especially in Pakistani population. This study was carried out to learn more about the disease characteristics in our area. This was a retrospective study where we reviewed four diagnosed and/or treated cases of primary thyroid Lymphoma at tertiary care hospital of Pakistan (Aga Khan University Hospital), Karachi, Pakistan. Each patient’s medical record was reviewed and studied. The participants' average age was 62.8 ± 10.12, with two males and two females. The histology of all of the patients was compatible with the Diffuse B cell Lymphoma subtype. ---Continue

Primary Thyroid Lymphoma: A Nationwide Retrospective Cohort Analysis of Survival and Determinant Factors

“…The prognosis of PTL varies widely depending on the lymphoma subtype, disease stage at diagnosis, and the patient's overall health. There are several case reports, case series and comprehensive reviews in the literature [1,2,7,12,21,[30][31][32], but original studies presenting prognostic data on a relatively high number of patients are scarce. The SEER database estimates a median overall survival of 9.3 years for PTL patients.…”