Hodgkin’s Lymphoma is a cancer affecting the lymphatic system. There are two subtypes of Hodgkin’s Lymphoma: Nodular lymphocyte predominant (NLPHL) and classical Hodgkin’s Lymphoma which has further four types. It has a bimodal distribution and is more common among males. The most common presentation is painless swelling in the neck, armpit or groin region. Associated Symptoms include night sweats, unintentional weight loss, fever, persistent cough or dyspnea. Involvement of the gastrointestinal tract is a rare occurrence. Diagnosis is based on hematological, radiological and histochemical studies.
Here we report a rare presentation of a 47-year-old male who presented with symptoms of loose stools, weight loss and fever. CT scan and abdominal lymph node biopsy findings were consistent with a lymphoproliferative disorder Patient was being managed in the line of malabsorption syndrome with possible underlying malignancy but his condition deterioted before the histological diagnosis was confirmed. Thus, this report highlights the importance having a consideration for Hodgkin’s lymphoma in the management of chronic diarrhea.
doi: https://doi.org/10.12669/pjms.38.8.5452
How to cite this:Furqan S, Khan SA, Ali D, Badini K. Chronic Diarrhea: A rare presentation of Hodgkin’s Lymphoma. Pak J Med Sci. 2022;38(8):---------. doi: https://doi.org/10.12669/pjms.38.8.5452
This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Primary Thyroid Lymphoma (PTL) is a rare disease, mostly affecting middle-to-old aged females. It has a strong association with pre-existing thyroiditis, which increases the risk of its development. The disease has been studied in detail in the Western populations. However, there is lack of data for south Asians, especially in Pakistani population. This study was carried out to learn more about the disease characteristics in our area. This was a retrospective study where we reviewed four diagnosed and/or treated cases of primary thyroid Lymphoma at tertiary care hospital of Pakistan (Aga Khan University Hospital), Karachi, Pakistan. Each patient’s medical record was reviewed and studied. The participants' average age was 62.8 ± 10.12, with two males and two females. The histology of all of the patients was compatible with the Diffuse B cell Lymphoma subtype.
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Background: Drug-induced uveitis is vision threatening and has been associated with various bioactive molecules. In this case report, we discuss a potential unique association between MiraLAX and bilateral anterior uveitis.
Case Presentation: We present a case of a 52-year-old gentleman with no significant medical history and a past ocular history of dry eye syndrome who developed an anaphylactic reaction and acute but mild bilateral anterior uveitis after recent MiraLAX bowel preparation for a screening colonoscopy. Extensive review of systems and screening for medical problems was otherwise unremarkable. The patient responded well to a short course of topical steroids and there were no sequelae of disease.
Conclusions: We aim to raise awareness of the potential association between MiraLAX and uveitis in order to prevent vision loss from the sequalae of disease.
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