Primary tumors of the thoracic skeleton

Abstract

From 1975 to 1990, eighty-nine primary tumors of the thoracic skeleton; ribs, sternum, scapula, clavicle, and thoracic spine, were treated. Forty-four tumors (49%) were benign lesions. Forty-five tumors were malignant and were proportionately distributed amongst the five sites. The most common malignancies were Ewing's sarcomas, chondrosarcomas, plasmacytomas, osteogenic sarcomas, and lymphomas. All patients with Ewing's sarcomas were treated with combination chemotherapy, surgical resection, and radiation therapy for those with residual disease after surgery. Only one patient has died of disease. Patients with primary chondrosarcomas were treated by surgery alone and all are free of disease or have died without disease. Patients with solitary plasmacytomas or primary lymphomas of bone were treated with radiation therapy initially. Half the patients developed systemic disease. The patients with osteogenic sarcomas included several with radiation induced lesions and Paget's osteosarcoma and all but one died of disease.

Unusual case of chondroblastic osteosarcoma of the rib in an adult

“…Doxorubicin and cisplatin are the agents of choice. 11 The overall prognosis of OS in flat bones remains poor because of the difficulty of complete excision in locations such as the skull and the pelvis. The guidelines for management and the prognosis and survival rates in primary OS of rib are not clear due to the small number of cases studied.…”

Solitary Plasmacytoma of the Sternum Detected Incidentally by MR Imaging of the Cervical Spine

“…Although literature review [1][2][3][8][9][10][11][12][13][14][15][16] indicates solitary plasmacytoma of the sternum to be rare, it should be considered in the diŠerential diagnosis when MR imaging detects signal abnormalities of the sternum.…”

Pulmonary Lymphoma: Primary and Systemic Disease

“…In a series of 89 patients with primary tumors of the skeleton, 4% were due to lymphomas. 69 This manifestation was associated with follicular lymphomas, and local control may be achieved with radiotherapy or chemotherapy.…”