Unusual case of chondroblastic osteosarcoma of the rib in an adult

Abstract

Primary osteosarcoma arising from the ribs is very rare. An unusual case of a primary chondroblastic osteosarcoma of the rib in a 30-year-old woman is described here. The patient underwent wide excision of the tumor along with the involved rib, followed by chemotherapy. Although clinically unsuspected in this unusual site, pathology confirmed a completely resected chondroblastic osteosarcoma.

The Management Challenges in an Unusual Case of Primary Osteosarcoma of the Rib in an Adult Patient

“…Approximately 10% of osteosarcomas localise in the flat bones, pelvis being the main site. Primary osteosarcomas of the ribs are infrequent and have been reported mainly in the paediatric population [1][2][3][4].…”

“…Around 10% of osteosarcomas are believed to arise from the flat bones, the most common site being the pelvis [1]. Involvement of flat bones like rib may be seen as a metastatic process or secondary to chemotherapy, but a primary osteosarcoma rib is extremely rare [2,3]. We report a case of primary osteosarcoma arising from the ribs of a 24-year-old male patient highlighting the therapeutic challenges along with a brief review of the literature.…”

Rare case of mandibular osteosarcoma: Clinical, imaging and pathological aspects

“…Because of this, the rapid bone growth is also attributed as a risk factor for the OS. This growth spurt occurs in younger stage and growth centers of the bones are the most affected areas, so the higher incidence of this type of injury in metaphyses of long bones [20].…”

“…Surgical excision margin of safety is the main treatment for OS [23][24][25] with local recurrence in approximately 60% of patients, usually during the first year after treatment. Survival rates at 5 years are reported average of 43% for OS gnathic [20,21].…”

Seeing the Invisible

“…[3][4][5][6][7] Osteosarcoma principally arises in the metaphysis of long bones, particularly at the lower femur, upper tibia, and humerus. 8 Its symptoms and radiographic features are nonspecific. 5 Depending on the relative amounts of osteoid, cartilage, or collagen fibers produced, OS histological types are fibroblastic, chondroblastic, osteoblastic, telangiectasic, and mixed.…”