Prior exercise does not affect chylomicron particle number following a mixed meal of moderate fat content

Abstract

Background: A single session of exercise has been reported to reduce fasting and postprandial triacylglycerol concentrations on the subsequent day. It is possible that exercise also reduces chylomicron particle number, which may underlie the observed reduction in postprandial triacylglycerol concentration. In the present study we aimed to determine whether a single session of exercise reduces fasting and postprandial chylomicron particle number on the subsequent day. In a randomised crossover design eight lean and healthy male and female subjects attended two postprandial testing days. On the previous day the subjects either performed 90 minutes of moderate intensity exercise or did not perform any exercise. Fasting blood samples were then collected prior to ingestion of a moderate fat mixed meal (0.44 g fat, 0.94 g carbohydrate, 0.27 g protein/kg body weight), blood was then collected after 1 h, 2 h, 4 h, 6 h, and 8 h.

Acute Effects of Shortly Pre- Versus Postprandial Aerobic Exercise on Postprandial Lipoprotein Metabolism in Healthy but Sedentary Young Women

“…The results contrast with the proposition that a single prior session of exercise (on the previous day) of moderate intensity for 90 min reduced fasting and, to a lesser extent, postprandial TG levels; however, the fasting and postprandial apoB48 concentration, a marker of the exogenous lipoprotein particle number, was not affected by prior exercise following a mixed meal of moderate fat content (0.44 g/kg body weight), suggesting no effect on the CM and CMR particle numbers 29) . As suggested, in a fat loading test, TG might be a poor surrogate of postprandial CM dynamics when considering cardiovascular risk factors.…”

Exercise prior to fat ingestion lowers fasting and postprandial VLDL and decreases adipose tissue IL-6 and GIP receptor mRNA in hypertriacylglycerolemic men

“…An additional metabolic process, on top of increased peripheral clearance, is likely responsible for the reduction in circulating TAG [35], as CM particles are preferentially bound to lipoprotein lipase before being cleared from the circulation [39]. Both large and small VLDL particles are decreased following moderate exercise [8], but the number of gut-derived TAG particles (fasting and postprandial) is not reduced following exercise despite a decreased fasting TAG concentration [40]. Exercise has been shown to alter fasting and postprandial TAG differently compared to energy restriction alone [38].…”

Low and moderate, rather than high intensity strength exercise induces benefit regarding plasma lipid profile

“…Both, acute and chronic effects of endurance exercise on the lipoprotein metabolism have been extensively documented and reviewed [15,16]. On the other hand, the effects of resistance exercise on the lipoprotein concentrations remain equivocal.…”