The exoneree population is growing rapidly, and legislatures are increasingly contemplating whether and how to better support exonerees, yet we know relatively little about exonerees’ mental health and other post-release needs. In this, the largest-ever study of exonerees, 59 exonerees completed measures of trauma exposure, PTSD, depression, perceived social support, posttraumatic cognitions, and personal history. Most exonerees (80%) reported having experienced trauma while incarcerated, and our measures classified half of exonerees as meeting criteria for probable PTSD (48-52%) and/or major depressive disorder (51%). Exonerees who reported stronger social support, weaker negative cognitions about the self and world, and/or full-time employment exhibited better mental health—but mental health was unrelated to time served, time since release, financial compensation, or false confession. Our findings underscore the fact that all exonerees need and deserve access to holistic and long-term transitional support. For clinicians, our findings also highlight specific psychotherapeutic approaches that may be effective with this population.