Pro- and Antioxidant Activity of Three Selected Flavan Type Flavonoids: Catechin, Eriodictyol and Taxifolin

Chobot, Vladimı́r; Hadaček, Franz; Bachmann, Gert; Weckwerth, Wolfram; Kubicová, Lenka

doi:10.3390/ijms17121986

Cited by 45 publications

(25 citation statements)

References 46 publications

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“…Peaks 4, 8, 9, 10, 11, 12, 14, 15, 17, 18, 19, 28, 32, 36, 39, 41, 44 and 45 represented different flavonoid compounds and their derivatives which possess diverse previously proven biological activities i.e., anti-inflammatory, anti-nociceptive, anti-oxidative, anti-dengue, anti-malarial [ 68 , 69 , 70 , 71 , 72 , 73 , 74 ]. Among them 3 bioactive compounds (peak 9, 18 and 39) were classified as 6-prenylated flavones (i.e., flavones that features a C5-isoprenoid substituent at the 6-position).…”

Section: Resultsmentioning

confidence: 99%

Microencapsulation and the Characterization of Polyherbal Formulation (PHF) Rich in Natural Polyphenolic Compounds

et al. 2018

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Microencapsulation of polyherbal formulation (PHF) extract was carried out by freeze drying method, by employing gum arabic (GA), gelatin (GE), and maltodextrin (MD) with their designated different combinations as encapsulating wall materials. Antioxidant components (i.e., total phenolic contents (TPC), total flavonoids contents (TFC), and total condensed tannins (TCT)), antioxidant activity (i.e., DPPH, β-carotene & ABTS+ assays), moisture contents, water activity (aw), solubility, hygroscopicity, glass transition temperature (Tg), particle size, morphology, in vitroα-amylase and α-glucosidase inhibition and bioavailability ratios of the powders were investigated. Amongst all encapsulated products, TB (5% GA & 5% MD) and TC (10% GA) have proven to be the best treatments with respect to the highest preservation of antioxidant components. These treatments also exhibited higher antioxidant potential by DPPH and β-carotene assays and noteworthy for an ABTS+ assays. Moreover, the aforesaid treatments also demonstrated lower moisture content, aw, particle size and higher solubility, hygroscopicity and glass transition temperature (Tg). All freeze dried samples showed irregular (asymmetrical) microcrystalline structures. Furthermore, TB and TC also illustrated the highest in vitro anti-diabetic potential due to great potency for inhibiting α-amylase and α-glucosidase activities. In the perspective of bioavailability, TA, TB and TC demonstrated the excellent bioavailability ratios (%). Furthermore, the photochemical profiling of ethanolic extract of PHF was also revealed to find out the bioactive compounds.

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Section: Resultsmentioning

confidence: 99%

Microencapsulation and the Characterization of Polyherbal Formulation (PHF) Rich in Natural Polyphenolic Compounds

et al. 2018

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“…Hydroxyl radicals scavenging capacity was determined according to Chobot, Hadacek, Bachmann, Weckwerth, and Kubicova (2016) by using the system 2‐deoxy‐D‐ribose/FeCl 3 /EDTA/H 2 O 2 /ascorbic acid with and without PE. The mixture was incubated at 37 °C for 60 min.…”

Section: Methodsmentioning

confidence: 99%

Zuccagnia‐type Propolis from Argentina: A potential functional ingredient in food to pathologies associated to metabolic syndrome and oxidative stress

Salas

Mercado

Orqueda

et al. 2020

Journal of Food Science

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The effect of Argentine propolis extracts against enzymes related to metabolic syndrome and oxidative stress, as well as the botanical origin of raw propolis, were studied. Histological and chemical analyses of propolis samples revealed that the botanical origin is Zuccagnia punctata, an Argentine medicinal plant. The melissopalynological analysis showed both pollen grains of Z. punctata and the other plant species. This result indicates that the differences found in the botanical remains compared to the palynological studies may have been caused by the bees selecting resinous shrubs mainly of Z. punctata for the production of propolis and other plants with flowers for the production of honey. The richness of propolis was remarkable in two flavonoid precursors (2´,4´‐dihydroxy‐3´‐methoxychalcone, 2´,4´‐dihydroxychalcone), the major chemical components of Z. punctata. The hydroalcoholic extracts of Argentine propolis and Z. punctata were able to inhibit enzymes associated with the metabolic syndrome, including α‐glucosidase, α‐amylase and lipase, with IC50 values between 7 to 14, 37 to 48, and 13 to 28 µg/mL, respectively. Biological activity was mainly attributed to chalcones. Oxygen and nitrogen reactive species scavenging activity was determined by the assays of superoxide radical (O2•−), hydroxyl radical (HO•), hydrogen peroxide (H2O2), nitric oxide (NO•), and cation radical (ABTS•+). Results showed SC50 values between 115 to 278, 12.50 to 46; 39 to 92; 50 to 104.50 and 23 to 33.75 µg/mL, respectively. This study suggests for the first time that propolis from Argentina is highly effective in inhibiting enzymes related to the metabolic syndrome and in free‐radical scavenging that would justify its use as a dietary supplement or as a functional ingredient in special food. Practical Application Propolis from Catamarca, Argentina, is traditionally used as medicine and food. Its botanical origin is Zuccagnia punctata, an endemic plant species popularly used as a medicine in Argentina. Propolis has the ability to regulate the activity of enzymes involved in the carbohydrate and lipid metabolism, and consequently in metabolic syndrome. Besides, its antioxidant capacity makes it a natural product that can be used as a dietary supplement or as a functional ingredient in special foods. It is important to highlight that in the Argentine Food Code, propolis was incorporated in 2008 as a dietary supplement and the present results give major added value to this product.

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“…After washing with a controlled volume of water, the amount of microparticles remained on the skin was evaluated; when compared with an untreated control, the extract was able to prevent the deposition of PM particles into the skin fine lines and wrinkles. The extracts of E. californicum, due to the presence of flavonoids such as homoeriodictyol and eriodictyol, well known for their antioxidant activity [76,77], provide further benefits when added to cosmetic formulations.…”

Section: Eriodictyon Californicummentioning

confidence: 99%

Cosmetic Functional Ingredients from Botanical Sources for Anti-Pollution Skincare Products

Juliano

Magrini

2018

Cosmetics

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Air pollution is a rising problem in many metropolitan areas around the world. Airborne contaminants are predominantly derived from anthropogenic activities, and include carbon monoxide, sulfur dioxide, nitrogen oxides, volatile organic compounds, ozone and particulate matter (PM; a mixture of solid and liquid particles of variable size and composition, able to absorb and delivery a large number of pollutants). The exposure to these air pollutants is associated to detrimental effects on human skin, such as premature aging, pigment spot formation, skin rashes and eczema, and can worsen some skin conditions, such as atopic dermatitis. A cosmetic approach to this problem involves the topical application of skincare products containing functional ingredients able to counteract pollution-induced skin damage. Considering that the demand for natural actives is growing in all segments of global cosmetic market, the aim of this review is to describe some commercial cosmetic ingredients obtained from botanical sources able to reduce the impact of air pollutants on human skin with different mechanisms, providing a scientific rationale for their use.

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Pro- and Antioxidant Activity of Three Selected Flavan Type Flavonoids: Catechin, Eriodictyol and Taxifolin

Cited by 45 publications

References 46 publications

Microencapsulation and the Characterization of Polyherbal Formulation (PHF) Rich in Natural Polyphenolic Compounds

Microencapsulation and the Characterization of Polyherbal Formulation (PHF) Rich in Natural Polyphenolic Compounds

Zuccagnia‐type Propolis from Argentina: A potential functional ingredient in food to pathologies associated to metabolic syndrome and oxidative stress

Cosmetic Functional Ingredients from Botanical Sources for Anti-Pollution Skincare Products

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