2018
DOI: 10.1016/j.actbio.2018.08.006
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Pro-angiogenic near infrared-responsive hydrogels for deliberate transgene expression

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Cited by 12 publications
(8 citation statements)
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“…Francisco et al recently demonstrated that the CuS NP/fibrinogen hydrogel increased the capillary density compared to the control group, suggesting that Cu 2+ can promote angiogenesis [ 141 ]. Huang et al expounded that the GelMA/GO-βCD-BNN6 hydrogel could achieve the controlled release of NO under NIR irradiation.…”
Section: Photothermal Hydrogels In Wound Healing and Bone Repairmentioning
confidence: 99%
“…Francisco et al recently demonstrated that the CuS NP/fibrinogen hydrogel increased the capillary density compared to the control group, suggesting that Cu 2+ can promote angiogenesis [ 141 ]. Huang et al expounded that the GelMA/GO-βCD-BNN6 hydrogel could achieve the controlled release of NO under NIR irradiation.…”
Section: Photothermal Hydrogels In Wound Healing and Bone Repairmentioning
confidence: 99%
“…The results confirmed that P407/CS/0.5Cu possessed a stronger ability to promote angiogenesis around the implanted site. Angiogenesis is supported by intricate interactions between transcription factors, cytokines, and enzymes, the functions of some of which appear to depend on copper bioavailability . In contrast to in vitro cellular simulated vascularization experiments, animal experiments mimic the internal microenvironment more adequately in which multiple cells are involved after fracture, such as endothelial cells (ECs), mesenchymal stem cells (MSCs), immune cells, etc .…”
Section: Resultsmentioning
confidence: 99%
“…Angiogenesis is supported by intricate interactions between transcription factors, cytokines, and enzymes, the functions of some of which appear to depend on copper bioavailability. 42 In contrast to in vitro cellular simulated vascularization experiments, animal experiments mimic the internal microenvironment more adequately in which multiple cells are involved after fracture, such as endothelial cells (ECs), mesenchymal stem cells (MSCs), immune cells, etc. 43 As it was confirmed in previous research studies that the expression of VEGF and BMP-2, two main regulation factors of angiogenesis and osteogenesis, was obviously enhanced in rat BMSCs via the overexpression of HIF-1α after being cocultured with Cu 2+ for 3 days.…”
Section: Hemostatic Performance Evaluationmentioning
confidence: 99%
“…It showed 22.7-fold improvement over solution phase reactions. Could provide scalable protein expression [57] Transcription and translation system for cellcell communication and collective behavior Tissue-like behavior involving task distribution, quorum sensing, and cellular differentiation by CFPS as nonliving mimics of eukaryotic cells [62] Biomimetic modeling systems Scaffold for cell encapsulation, delivery, gene regulation Thermal-responsive fibrin-based hydrogel can be used as a scaffold for cell delivery and controlled transgene expression to promote tissue healing [83] Scaffolds for cell culture, delivery, and recovery, transplantation…”
Section: Microarray (High-throughput Analysis): Capturing Sequencing ...mentioning
confidence: 99%
“…This fibrin‐based hydrogel was used for simultaneous encapsulation and heat‐induced controlled expression of the genes required for vascularization to promote tissue repair in mice. [ 83 ]…”
Section: Bioresponsive Multitasking Hydrogels In the New Era Of Biome...mentioning
confidence: 99%