The purpose of study is to determine the effect of structural and psychological empowerment on career satisfaction and innovative work behavior. In order to test the research hypotheses, data were collected from the white-collar employees in the production businesses by survey method. As a result of the analysis, it is found that structural empowerment and psychological empowerment has a positive effect with career satisfaction and innovative work behavior. In this study, two models were examined by comparison. The first model is whether psychological empowerment has an mediator variable effect on the relationship between structural empowerment and career satisfaction and innovative work behavior. The second model is whether career satisfaction has an mediator variable effect on the relationship between structural and psychological empowerment and innovative work behavior. In order to test the models, hierarchical regression analysis was performed. As a result of these analyzes, it was found that psychological empowerment and career satisfaction had an mediator role among the variables.