Probiotics: Properties, Examples, and Specific Applications

Behnsen, Judith; Deriu, Elisa; Sassone‐Corsi, Martina; Raffatellu, Manuela

doi:10.1101/cshperspect.a010074

Cited by 229 publications

(165 citation statements)

References 130 publications

(127 reference statements)

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“…These intentional administrations with natural bacteria have been mostly performed with strains of lactic acid bacteria (LAB) (e.g. Lactobacillus, Bifidobacterium ) but also with Escherichia coli strains, such as E. coli Nissle 1917 (EcN; Behnsen et al ., 2013; Ou et al ., 2016; Sonnenborn, 2016). These strains usually have limited therapeutic effects by themselves, but they have clearly proven to be safe, and thus represent excellent chassis for synthetic biology engineering (Chua et al ., 2017).…”

Section: Engineering Bacteria and The Microbiomementioning

confidence: 99%

Sustainable therapies by engineered bacteria

Álvarez

Fernández

2017

Microbial Biotechnology

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SummaryThe controlled in situ delivery of biologics (e.g. enzymes, cytokines, antibodies) by engineered bacteria of our microbiome will allow the sustainable production of these complex and expensive drugs locally in the human body, overcoming many of the technical and economical barriers currently associated with the global use of these potent medicines. We provide examples showing how engineered bacteria can be effective treatments against multiple pathologies, including autoimmune and inflammatory diseases, metabolic disorders, diabetes, obesity, infectious diseases and cancer, hence contributing to achieve the Global Sustainable Goal 3: ensure healthy lives and promote well‐being for all at all ages.

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Section: Engineering Bacteria and The Microbiomementioning

confidence: 99%

Sustainable therapies by engineered bacteria

Álvarez

Fernández

2017

Microbial Biotechnology

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“…(Azizpour K et al, 2009, Behnsen J et al, 2013 The probiotic should exert positive effects on the host. It should be acid resistant, bile resistant and contain a minimum 30×10 9 CFU/ Gram.…”

Section: Saccharomyces Boulardiimentioning

confidence: 99%

Role of Probiotics in human health and disease: An update

Faujdar¹,

Mehrishi²,

Bishnoi³

et al. 2016

Int.J.Curr.Microbiol.App.Sci

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“…Most probiotics are lactic bacteria, such as Lactobacillus casei, Lactobacillus plantarum, Lactobacillus acidophilus and Streptococcus lactis [3,4]. Several research studies have shown that the addition of probiotic sources in the diet provides beneficial effects such as; the inhibition of the proliferation of pathogenic microbes in the digestive tract, the reduction of the blood cholesterol, the improvement of the immune system and the reduction of the risks of cancer of the colon [5][6][7][8]. Fermented foods are sources of various microbial strains of food and industrial interest.…”

Section: Introductionmentioning

confidence: 99%

Probiotic potential of thermotolerant lactic acid bacteria isolated from “Gari “a cassava-based African fermented food

2017

J App Biol Biotech

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Most of the probiotic products undergo industrial processing involving high temperatures. Thermotolerance of probiotic microorganisms used in such processing is important to make it effective during consumption or administration. Very few studies have been devoted to the thermotolerance of probiotics. This work aimed at assessing the thermotolerance and probiotic potential of lactic acid bacteria isolated from "Gari" produced in the South West Region of Cameroon. Lactic acid bacteria were isolated from "Gari" samples using pour plate method on De Man Rogosa and Sharpe (MRS) agar. The catalase negative colonies were selected and subjected to thermotolerance test by heating the cells suspended in MRS broth at temperatures ranged from 50-60 °C for 1h and measurement of their growth at 30 °C by spectrophotometry. Only two isolates (SB1 and SB2) were able to tolerate heating treatment at 50-56°C and were selected. They were respectively identified using API 50 CHL BioMerieux kit as strain of Lactobacillus plantarum and Lactobacillus acidophilus. These selected strains showed high inhibitory activity against important food borne pathogenic bacteria such as Salmonella enterica serovar Enteritidis, Salmonella enterica serovar Typhimurium, Esherichia coli, Satphylococcus aureus and a food spoilage microorganisms; Listeria monocytogenes with an average inhibition diameter greater than 15 mm. The selected probiotic lactic acid bacteria also tolerate pH3.0 and 0.3 % (v/v) oxgall-bile. Owing to their properties they may be used in industrial processing of probiotic products.

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Probiotics: Properties, Examples, and Specific Applications

Cited by 229 publications

References 130 publications

Sustainable therapies by engineered bacteria

Sustainable therapies by engineered bacteria

Role of Probiotics in human health and disease: An update

Probiotic potential of thermotolerant lactic acid bacteria isolated from “Gari “a cassava-based African fermented food

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