Role of Probiotics in human health and disease: An update

Faujdar, Sameer Singh; Mehrishi, Priya; Bishnoi, Surabhi; Sharma, Amisha

doi:10.20546/ijcmas.2016.503.040

Cited by 15 publications

(6 citation statements)

References 42 publications

(42 reference statements)

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“…The majority of probiotics are from the genera Lactobacillus and Bifidobacterium. The potential roles of probiotics may include prevention and assisting in treatments of various diseases such as gastrointestinal infections, inflammatory bowel disease, lactose intolerance, urogenital infections, cancers, cystic fibrosis, dental caries, oral bad odors, and antibiotic side effects [7,59]. Probiotics can also be used as an adjuvant with vaccines.…”

Section: The General View About Probioticsmentioning

confidence: 99%

Ameliorating effects of probiotics on alterations in iron homeostasis and inflammation in COVID-19

El-Sayed

Ibrahim

2022

Mol Biol Rep

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IntroductionThe coronavirus disease (COVID-19) is caused by the severe acute syndrome coronavirus-2 (SARS-COV-2) and still threatens human life. This pandemic is still causing increased mortality throughout the world. Many recent studies have been conducted to discover the pathophysiology of this virus. Material and methods However, in this narrative review, we attempted to summarize some of the alterations in physiological pathways that were evident in this viral invasion. Excessive inflammation that progresses to cytokine storm, changes in humoral and cell-mediated immunity, and observed alterations in iron metabolism are included in the pathogenesis of the virus. Iron homeostasis disturbances may persist for more than two months after the onset of COVID-19, which may lead to reduced iron bioavailability, hypoferremia, hyperferritinemia, impaired hemoglobin, and red blood cell synthesis. Furthermore, hypoferriemia may impair immune system function. Until now, the traditional treatments discovered are still being tried. Results However, using probiotics as an adjuvant was shown to have beneficial effects on both iron homeostasis and immunity in COVID-19. Herein, we discussed the possible mechanisms achieved by probiotics to ameliorate iron and immunity changes based on the available literature. Conclusion We concluded that supplementing probiotics with conventional therapy may improve COVID-19 symptoms and outcomes. Taking into consideration the use of good quality probiotics and appropriate dosage, undesirable effects can be avoided.

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Section: The General View About Probioticsmentioning

confidence: 99%

Ameliorating effects of probiotics on alterations in iron homeostasis and inflammation in COVID-19

El-Sayed

Ibrahim

2022

Mol Biol Rep

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“…Prebiotik merupakan bahan pangan yang tidak dapat dicerna di dalam saluran pencernaan sehingga dapat menstimulasi pertumbuhan dan aktivitas bakteri probiotik pada kolon manusia (Robertfroid 2007). Prebiotik diyakini sebagai bahan pangan yang dapat memberikan dampak positif bagi kesehatan karena terbukti mengurangi risiko beberapa penyakit, seperti diare, osteoporosis, obesitas dan kanker kolon (Faudjar et al 2016, O' Bryan et al 2013, Russel et al 2013. Selain itu, prebiotik juga dianggap mampu meningkatkan imunitas dan proteksi sistem urogenital manusia (Duncan dan Flint 2014).…”

Section: Pendahuluanunclassified

Optimasi Konsentrasi Fruktooligosakarida untuk Meningkatkan Pertumbuhan Bakteri Asam Laktat Starter Yoghurt (CONCENTRATION OPTIMIZATION OF FRUCTOOLIGOSACCHARIDES TO INCREASE GROWTH OF LACTIC ACID BACTERIA YOGHURT STARTER)

Setiarto¹,

Widhyastuti²,

Rikmawati³

2017

JVet

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Fructooligosaccharides are prebiotic source that widely used in food products, such as: fermented milk and infant formula. Prebiotics are food components that cannot be digested in the digestive tract enzymatically. However, they can be fermented by probiotic bacteria in the colon. This study aimed to determine the optimum concentrations of fructooligosaccharides in order to increase the growth of lactic acid bacteria yogurt starter (Lactobacillus acidophillus, Lactobacillus bulgaricus, Streptococcus thermophillus). Optimation concentration of fructooligosaccharides on the growth of Lactobacillus acidophilus, Lactobacillus bulgaricus, Streptococcus thermophillus can be determined based on OD (optical density), TPC (Total Plate Count), total lactic acid content and pH value. Suplementation of fructooligosaccharides 1 % (w/v) on the media MRSB increased significantly the growth of L. acidophilus, L.bulgaricus, S. thermophilus. Furthermore, L. acidophilus, L. bulgaricus and S. thermophilus experienced exponential growth phase during incubation period from 6 to 18 hours. Fermentation of L. acidophilus, L. bulgaricus, S. thermophilus in MRSB medium supplemented by fructooligosaccharides decreased the pH value of the formation of organic acids from 6.00 to 4.00. ABSTRAK Fruktooligosakarida adalah sumber prebiotik yang banyak digunakan dalam produk pangan olahan seperti susu fermentasi dan susu formula. Prebiotik adalah komponen bahan pangan fungsional yang tidak dapat dicerna di dalam saluran pencernaan secara enzimatik sehingga akan difermentasi oleh bakteri probiotik dalam usus besar. Penelitian ini bertujuan menentukan konsentrasi optimum fruktooligosakarida untuk meningkatkan pertumbuhan bakteri asam laktat starter yoghurt (Lactobacillus acidophillus, Lactobacillus bulgaricus, Streptococcus thermophillus). Konsentrasi optimum fruktooligosakarida pada pertumbuhan Lactobacillus acidophilus, Lactobacillus bulgaricus, Streptococcus thermophillus dapat ditentukan berdasarkan OD (optical density), TPC (Total Plate Count), total asam laktat tertitrasi dan nilai pH. Penambahan fruktooligosakarida 1% (b/v) pada media MRSB (Man, Rogosa Sharpe Broth) dapat meningkatkan secara signifikan pertumbuhan L. acidophilus, L. bulgaricus, S. thermophilus. Bakteri asam laktat L. acidophilus, L. bulgaricus dan S. thermophilus mengalami fase pertumbuhan eksponensial selama masa inkubasi 6-18 jam. Fermentasi L. acidophilus, L. bulgaricus, S. thermophilus pada MRSB dengan penambahan fruktooligosakarida dapat menurunkan nilai pH dari kisaran 6,00 hingga 4,00 karena pembentukan asam-asam organik.

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“…Probiotics are living microorganisms that exhibit a symbiotic relationship and balance the human intestinal microbiota [1,2]. There are many beneficial effects of probiotics on human life [3]. Probiotics induce the bioconversion of ingested food into an easily digested and absorbed form in the human intestine and inhibit the production of cholesterol and the growth of harmful bacteria or pathogens in the intestine that cause various diseases [1,4].…”

Section: Introductionmentioning

confidence: 99%

Lactobacillus rhamnosus CBT-LR5 Improves Lipid Metabolism by Enhancing Vitamin Absorption

Kim

Yoon

et al. 2022

Microbiol. Biotechnol. Lett.

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Probiotics provide a symbiotic relationship and beneficial effects by balancing the human intestinal microbiota. The relationships between microbiota changes and various diseases may predict health abnormalities and diseases. Treatment with vitamins and probiotics is one therapeutic approach. To evaluate the effect of probiotics on vitamin absorption, we chose Lactobacillus rhamnosus CBT-LR5 treatment, which has resistance to vitamin C-inducible toxicity, with vitamins in high-fat diet (HFD)-induced obesity models. CBT-LR5 affected the absorption of micronutrients, such as ionic minerals and water-soluble vitamins. An increase in vitamin C absorption by CBT-LR5 enhanced the antioxidant response in HFD-induced obesity models. Increased vitamin B absorption by CBT-LR5 regulated lipid metabolism in HFD-induced obesity models. These favorable effects of CBT-LR5 on the absorption of vitamins should be investigated as candidate therapeutic target treatments for metabolic diseases.

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Role of Probiotics in human health and disease: An update

Cited by 15 publications

References 42 publications

Ameliorating effects of probiotics on alterations in iron homeostasis and inflammation in COVID-19

Ameliorating effects of probiotics on alterations in iron homeostasis and inflammation in COVID-19

Optimasi Konsentrasi Fruktooligosakarida untuk Meningkatkan Pertumbuhan Bakteri Asam Laktat Starter Yoghurt (CONCENTRATION OPTIMIZATION OF FRUCTOOLIGOSACCHARIDES TO INCREASE GROWTH OF LACTIC ACID BACTERIA YOGHURT STARTER)

Lactobacillus rhamnosus CBT-LR5 Improves Lipid Metabolism by Enhancing Vitamin Absorption

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