Problems Experienced by Babies Between 4-36 Months  During Teething Process and the Practices Made by Mothers

Erkut, Zeynep; Köse, Selmin; Dumandağ, Fatma

doi:10.46483/deuhfed.868669

Cited by 1 publication

(1 citation statement)

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“…In this natural process, many local and systemic symptoms can be seen in infants and young children. Local symptoms such as an increase in the amount of saliva experienced during this period, irritation in the gums, an increase in the desire to chew and bite, and systemic symptoms such as fever, diarrhea, vomiting, insomnia, restlessness, rashes in the body, and loss of appetite are often associated with this period [ 4 – 6 ].…”

Section: Introductionmentioning

confidence: 99%

An in vitro assessment of teething gels’ effects on human gingival mesenchymal stem cells

Birant,

İlisulu,

Kılıç

et al. 2024

BMC Oral Health

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Background The aim of this study is to examine the cytotoxic effects of dental gels with different contents, which are frequently used during teething, on gingival mesenchymal stem cells (G-MSCs). Method The teething gels used in this study were Dentinox, Gengigel, Osanite, and Jack and Jill. The human gingival mesenchimal stem cells (hG-MSCs) were incubated with these teething gel solutions (0.1%, 50% and 80% concentrations). Reproductive behavior of G-MSCs was monitored in real time for 72 h using the xCELLigence real-time cell analyzer (RTCA) system. Two-way repeated Anova test and post hoc Bonferroni test were used to evaluate the effect of concentration and dental gel on 0-hour and 72-hour viability. Significance was evaluated at p < 0.05 level. Results Teething gels prepared at 50% concentration are added to the G-MSC culture, the “cell index” value of G-MSCs to which Dentinox brand gel is added is significantly lower than all other groups (p = 0.05). There is a statistically significant difference between the concentrations in terms of cell index values at the 72nd hour compared to the 0th hour (p = 0.001). Conclusions The local anesthetic dental gels used in children have a more negative effect on cell viability as concentration increases.

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Section: Introductionmentioning

confidence: 99%